{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T15:06:39Z","timestamp":1753887999265,"version":"3.41.2"},"reference-count":10,"publisher":"FapUNIFESP (SciELO)","license":[{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"am","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. vasc. bras."],"abstract":"<jats:p>Abstract Chronic ulcerations of the lower extremities are quite a common condition amongst adults, most often caused by chronic venous insufficiency. Irrespective of the main underlying cause, chronic limb ulcerations are usually associated with significant symptoms, impairing daily functioning. Improper or delayed diagnosis and inadequate treatment increase the risk of serious complications, including limb amputations. Malignancies can develop secondary to chronic leg ulcers. About 2.4% of ulcers arising from chronic venous stasis undergo malignant transformation. Squamous cell carcinoma is the most common type of malignancy found in chronic leg ulceration biopsies. Basal cell carcinoma, sarcoma, and melanoma have all been documented infrequently. In the case described here, we found lymphoma of the marginal zone of mucosa-associated lymphoid tissue (MALT), which is an extremely rare cutaneous neoplasm of the lower extremities, but one that may have an association with autoimmune diseases.<\/jats:p>","DOI":"10.1590\/1677-5449.210003","type":"journal-article","created":{"date-parts":[[2021,7,12]],"date-time":"2021-07-12T12:06:57Z","timestamp":1626091617000},"source":"Crossref","is-referenced-by-count":0,"title":["Atypical presentation of Sjogren\u2019s syndrome with MALT lymphoma mimicking chronic venous ulcers"],"prefix":"10.1590","volume":"20","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0220-4336","authenticated-orcid":false,"given":"Marta","family":"Wasilewska","sequence":"first","affiliation":[{"name":"Wroclaw Medical University,  Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"530","published-online":{"date-parts":[[2021]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","DOI":"10.1155\/2013\/413604","article-title":"Chronic leg ulcers: epidemiology, aetiopathogenesis, and management","volume":"2013","author":"Agale SV","year":"2013","journal-title":"Ulcers"},{"issue":"3","key":"ref2","doi-asserted-by":"crossref","first-page":"388","DOI":"10.1046\/j.1365-2133.2003.05222.x","article-title":"Causes, investigation and treatment of leg ulceration","volume":"148","author":"Mekkes JR","year":"2003","journal-title":"Br J Dermatol"},{"issue":"4","key":"ref3","first-page":"E30","article-title":"at al. Basal cell carcinoma arising in a chronic venous ulcer: two cases and a review of the literature","volume":"26","author":"Poccia I","year":"2014","journal-title":"Wounds"},{"issue":"2","key":"ref4","first-page":"75","article-title":"Cutaneous cancers and chronic leg ulcers","volume":"21","author":"Senet P","year":"2014","journal-title":"Phlebolymphology"},{"issue":"4","key":"ref5","doi-asserted-by":"crossref","first-page":"e9","DOI":"10.1308\/003588411X13008889959172","article-title":"Diffuse large B-cell lymphoma presenting as a chronic leg ulcer: the importance of repeat tissue biopsy","volume":"93","author":"Khan JA","year":"2011","journal-title":"Ann R Coll Surg Engl"},{"issue":"3","key":"ref6","doi-asserted-by":"crossref","first-page":"187","DOI":"10.25122\/jml-2018-0035","article-title":"MALT lymphoma: epidemiology, clinical diagnosis and treatment","volume":"11","author":"Filip PV","year":"2018","journal-title":"J Med Life"},{"issue":"1","key":"ref7","first-page":"32","article-title":"Ch\u0142oniak typu MALT oczodo\u0142u: opis przypadku i przegl\u0105d pi\u015bmiennictwa","volume":"3","author":"Bednaruk-M\u0142y\u0144ski E","year":"2007","journal-title":"Onkologia w Praktyce Klinicznej."},{"key":"ref8","first-page":"153","article-title":"Primary MALT type skin lymphoma-is \u2018wait and see\u2019 a possible strategy?","volume":"2","author":"Delli FS","year":"2008","journal-title":"Clin Med Oncol"},{"issue":"4","key":"ref9","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1016\/j.jdcr.2017.02.024","article-title":"Primary cutaneous marginal zone lymphoma with leptomeningeal involvement and a durable response to rituximab","volume":"3","author":"Virmani P","year":"2017","journal-title":"JAAD Case Rep"},{"issue":"2","key":"ref10","doi-asserted-by":"crossref","first-page":"766","DOI":"10.1182\/blood.V90.2.766","article-title":"Lymphomas in patients with Sjogren\u2019s syndrome are marginal zone B-cell neoplasms, arise in diverse extranodal and nodal Sites, and are not associated with viruses","volume":"90","author":"Royer B","year":"1997","journal-title":"Blood"}],"container-title":["Jornal Vascular Brasileiro"],"original-title":[],"link":[{"URL":"http:\/\/www.scielo.br\/pdf\/jvb\/v20\/1677-5449-jvb-20-e20210003.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,7,12]],"date-time":"2021-07-12T12:07:10Z","timestamp":1626091630000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.scielo.br\/scielo.php?script=sci_arttext&pid=S1677-54492021000100624&tlng=en"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021]]},"references-count":10,"alternative-id":["S1677-54492021000100624"],"URL":"https:\/\/doi.org\/10.1590\/1677-5449.210003","relation":{},"ISSN":["1677-7301","1677-5449"],"issn-type":[{"type":"electronic","value":"1677-7301"},{"type":"print","value":"1677-5449"}],"subject":[],"published":{"date-parts":[[2021]]},"article-number":"e20210003"}}