{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T15:08:06Z","timestamp":1753888086915,"version":"3.41.2"},"reference-count":43,"publisher":"FapUNIFESP (SciELO)","license":[{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"am","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. vasc. bras."],"abstract":"<jats:p>Resumo A ponte de tirofiban \u00e9 uma alternativa \u00e0 suspens\u00e3o da terapia antiplaquet\u00e1ria dupla no perioperat\u00f3rio de pacientes com alto risco de trombose de stent e de sangramento. Objetivamos avaliar a efic\u00e1cia e a seguran\u00e7a deste protocolo em pacientes submetidos \u00e0 cirurgia em at\u00e9 12 meses ap\u00f3s interven\u00e7\u00e3o coron\u00e1ria percut\u00e2nea com stent. Realizamos uma revis\u00e3o sistem\u00e1tica por meio de pesquisa nas bases PubMed, Web of Science, Cochrane, EMBASE, LILACS e SciELO e nas refer\u00eancias de artigos relevantes ao tema. Dos 107 trabalhos encontrados, cinco foram inclu\u00eddos ap\u00f3s an\u00e1lise dos crit\u00e9rios de elegibilidade e da qualidade metodol\u00f3gica, totalizando 422 pacientes, sendo 227 do grupo controle. Apesar das limita\u00e7\u00f5es reportadas, quatro dos cinco estudos inclu\u00eddos indicam que a ponte de tirofiban \u00e9 eficaz em reduzir eventos card\u00edacos adversos e segura ao n\u00e3o interferir no risco de eventos hemorr\u00e1gicos ou sangramentos. Todavia, s\u00e3o necess\u00e1rios ensaios cl\u00ednicos randomizados para evid\u00eancias robustas.<\/jats:p>","DOI":"10.1590\/1677-5449.210113","type":"journal-article","created":{"date-parts":[[2021,12,1]],"date-time":"2021-12-01T12:16:41Z","timestamp":1638361001000},"source":"Crossref","is-referenced-by-count":1,"title":["Efic\u00e1cia e seguran\u00e7a da ponte de tirofiban como alternativa \u00e0 suspens\u00e3o da terapia antiplaquet\u00e1ria dupla em pacientes submetidos \u00e0 cirurgia: uma revis\u00e3o sistem\u00e1tica"],"prefix":"10.1590","volume":"20","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6944-1416","authenticated-orcid":false,"given":"Lorrane Vieira Siqueira","family":"Riscado","sequence":"first","affiliation":[{"name":"Universidade Federal de Juiz de Fora,  Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4245-1080","authenticated-orcid":false,"given":"Jo\u00e3o Henrique Sendrete de","family":"Pinho","sequence":"additional","affiliation":[{"name":"Universidade Federal de Juiz de Fora,  Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1672-1841","authenticated-orcid":false,"given":"Armando de Carvalho","family":"Lobato","sequence":"additional","affiliation":[{"name":"Instituto de Cirurgia Vascular e Endovascular de S\u00e3o Paulo,  Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"530","published-online":{"date-parts":[[2021]]},"reference":[{"issue":"23","key":"ref1","doi-asserted-by":"crossref","first-page":"2155","DOI":"10.1056\/NEJMoa1409312","article-title":"Twelve or 30 months of dual antiplatelet therapy after drug-eluting stents","volume":"371","author":"Mauri L","year":"2014","journal-title":"N Engl J Med"},{"issue":"7329","key":"ref2","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1136\/bmj.324.7329.71","article-title":"Collaborative meta-analysis of randomised trials 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