{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,20]],"date-time":"2026-09-20T17:37:33Z","timestamp":1789925853007,"version":"4.0.1"},"reference-count":19,"publisher":"FapUNIFESP (SciELO)","license":[{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"am","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. vasc. bras."],"abstract":"<jats:p>Abstract Syphilitic aortitis is a rare complication of tertiary syphilis, which can lead to aortic aneurysm formation, aortic valvular insufficiency, and ostial coronary stenosis. Syphilis has re-emerged worldwide over recent decades and vascular surgeons should be aware of its cardiovascular manifestations. Atypical clinical presentation, such as hemoptysis and a computed tomography angiography pattern of a thicker aneurysmal wall with ulcer-like aneurysm projections, should raise suspicion of syphilitic aortic aneurysm. An early diagnosis and appropriate surgical and medical therapies significantly contribute to successful treatment and favorable prognosis. Herein is reported the case of an 82-year-old male patient, positive for syphilis infection, with impending aortic arch aneurysm rupture treated with a hybrid arch repair. After 7 months, the patient was brought to the emergency room in cardiac arrest. Unsuccessful cardiopulmonary resuscitation maneuvers were performed, and an autopsy showed cardiac tamponade due to rupture of the ascending aorta.<\/jats:p>","DOI":"10.1590\/1677-5449.210160","type":"journal-article","created":{"date-parts":[[2022,1,7]],"date-time":"2022-01-07T12:09:27Z","timestamp":1641557367000},"source":"Crossref","is-referenced-by-count":5,"title":["Contained rupture of an aortic arch aneurysm in a patient with syphilitic aortitis. A case report"],"prefix":"10.1590","volume":"20","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6643-394X","authenticated-orcid":false,"given":"Victor","family":"Bilman","sequence":"first","affiliation":[{"name":"\u201cVita \u2013 Salute\u201d University,  Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luca","family":"Bertoglio","sequence":"additional","affiliation":[{"name":"\u201cVita \u2013 Salute\u201d University,  Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Germano","family":"Melissano","sequence":"additional","affiliation":[{"name":"\u201cVita \u2013 Salute\u201d University,  Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roberto","family":"Chiesa","sequence":"additional","affiliation":[{"name":"\u201cVita \u2013 Salute\u201d University,  Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"530","published-online":{"date-parts":[[2021]]},"reference":[{"issue":"2","key":"ref1","doi-asserted-by":"crossref","first-page":"e27","DOI":"10.1016\/j.jtcvs.2017.04.052","article-title":"Syphilitic aortitis: the bigger picture","volume":"154","author":"Girardi LN","year":"2017","journal-title":"J Thorac Cardiovasc Surg"},{"issue":"8","key":"ref2","doi-asserted-by":"crossref","first-page":"741","DOI":"10.1007\/s00393-018-0519-1","article-title":"Syphilitic aortic aneurysm","volume":"77","author":"Yuan SM","year":"2018","journal-title":"Z Rheumatol"},{"issue":"8","key":"ref3","doi-asserted-by":"crossref","first-page":"1298","DOI":"10.1016\/j.amjcard.2015.07.030","article-title":"Syphilis as a cause of thoracic aortic aneurysm","volume":"116","author":"Roberts WC","year":"2015","journal-title":"Am J Cardiol"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"255","DOI":"10.2147\/VHRM.S289455","article-title":"Impending aortic rupture in a patient with syphilitic aortitis","volume":"17","author":"Cocora M","year":"2021","journal-title":"Vasc Health Risk Manag"},{"issue":"2","key":"ref5","doi-asserted-by":"crossref","first-page":"e23","DOI":"10.1016\/j.jtcvs.2017.03.134","article-title":"Massive hemoptysis related to contained rupture of syphilitic aortic aneurysm into the pulmonary parenchyma","volume":"154","author":"\u0130sbir S","year":"2017","journal-title":"J Thorac Cardiovasc Surg"},{"issue":"5","key":"ref6","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1016\/j.carpath.2015.05.001","article-title":"Consensus statement on surgical pathology of the aorta from the Society for Cardiovascular Pathology and the Association for European Cardiovascular Pathology: I. Inflammatory diseases","volume":"24","author":"Stone JR","year":"2015","journal-title":"Cardiovasc Pathol"},{"issue":"5","key":"ref7","doi-asserted-by":"crossref","first-page":"898","DOI":"10.1016\/j.amjcard.2018.05.030","article-title":"Operative recognition of syphilis of the aorta","volume":"122","author":"Roberts WC","year":"2018","journal-title":"Am J Cardiol"},{"key":"ref8","doi-asserted-by":"crossref","DOI":"10.1016\/j.carpath.2019.107175","article-title":"Syphilitic aortitis: still a current common cause of aneurysm of the tubular portion of ascending aorta","volume":"46","author":"Roberts WC","year":"2020","journal-title":"Cardiovasc Pathol"},{"issue":"8","key":"ref9","doi-asserted-by":"crossref","first-page":"1298","DOI":"10.1016\/j.amjcard.2015.07.030","article-title":"Syphilis as a cause of thoracic aortic aneurysm","volume":"116","author":"Roberts WC","year":"2015","journal-title":"Am J Cardiol"},{"issue":"5","key":"ref10","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1055\/s-0039-1683399","article-title":"Syphilitic aortic aneurysm in the Third Millennium","volume":"6","author":"Del Re F","year":"2018","journal-title":"Aorta"},{"issue":"3","key":"ref11","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1590\/S0102-76382010000300021","article-title":"Syphilitic aortitis: diagnosis and treatment. Case report","volume":"25","author":"Saraiva RS","year":"2010","journal-title":"Rev Bras Cir Cardiovasc"},{"issue":"3","key":"ref12","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1016\/j.bjid.2017.01.003","article-title":"Aneurysm and dissection in a patient with syphilitic aortitis","volume":"21","author":"Pivatto Jr F","year":"2017","journal-title":"Braz J Infect Dis"},{"issue":"3","key":"ref13","article-title":"Syphilitic aortic aneurysm: a rare entity in the era of antibiotics","volume":"13","author":"Chaudhary F","year":"2021","journal-title":"Cureus"},{"issue":"2","key":"ref14","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1097\/CM9.0000000000000993","article-title":"Total arch replacement with stented elephant trunk technique for syphilitic thoracic aortic aneurysm","volume":"134","author":"Tang YF","year":"2020","journal-title":"Chin Med J"},{"issue":"3","key":"ref15","doi-asserted-by":"crossref","first-page":"346","DOI":"10.1161\/01.CIR.29.3.346","article-title":"Syphilitic aortitis: a clinicopathologic autopsy study of 100 cases, 1950 to 1960","volume":"29","author":"Heggtveit H","year":"1964","journal-title":"Circulation"},{"issue":"3","key":"ref16","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1016\/S0950-821X(88)80077-X","article-title":"Syphilitic aneurysm of the abdominal aorta: report of two cases","volume":"2","author":"Marconato R","year":"1988","journal-title":"Eur J Vasc Surg"},{"key":"ref17","doi-asserted-by":"crossref","first-page":"279.e13","DOI":"10.1016\/j.avsg.2017.07.041","article-title":"Rare Presentation of a Syphilitic Aneurysm of the Infrarenal Aorta with Contained Rupture","volume":"47","author":"Chitragari G","year":"2018","journal-title":"Ann Vasc Surg"},{"issue":"2","key":"ref18","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1016\/j.ejvs.2018.09.016","article-title":"Editor\u2019s Choice \u2013 Current Options and Recommendations for the Treatment of Thoracic Aortic Pathologies Involving the Aortic Arch: An Expert Consensus Document of the European Association for Cardio-Thoracic Surgery (EACTS) & the European Society for Vascu","volume":"57","author":"Czerny M","year":"2019","journal-title":"Eur J Vasc Endovasc Surg"},{"issue":"1","key":"ref19","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1016\/j.jvs.2019.08.273","article-title":"The risk of aneurysm rupture and target visceral vessel occlusion during the lead period of custom-made fenestrated\/branched endograft","volume":"72","author":"Gallitto E","year":"2020","journal-title":"J Vasc Surg"}],"container-title":["Jornal Vascular Brasileiro"],"original-title":[],"deposited":{"date-parts":[[2022,1,7]],"date-time":"2022-01-07T12:09:40Z","timestamp":1641557380000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.scielo.br\/scielo.php?script=sci_arttext&pid=S1677-54492021000100638&tlng=en"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021]]},"references-count":19,"alternative-id":["S1677-54492021000100638"],"URL":"https:\/\/doi.org\/10.1590\/1677-5449.210160","relation":{},"ISSN":["1677-7301","1677-5449"],"issn-type":[{"value":"1677-7301","type":"electronic"},{"value":"1677-5449","type":"print"}],"subject":[],"published":{"date-parts":[[2021]]},"article-number":"e20210160"}}