{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,2]],"date-time":"2026-04-02T16:36:49Z","timestamp":1775147809305,"version":"3.50.1"},"reference-count":27,"publisher":"FapUNIFESP (SciELO)","issue":"2","license":[{"start":{"date-parts":[[2019,1,1]],"date-time":"2019-01-01T00:00:00Z","timestamp":1546300800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2019,1,1]],"date-time":"2019-01-01T00:00:00Z","timestamp":1546300800000},"content-version":"am","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2019,1,1]],"date-time":"2019-01-01T00:00:00Z","timestamp":1546300800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. bras. pneumol."],"abstract":"<jats:p>ABSTRACT  Objective: To evaluate the treatment compliance of patients with paracoccidioidomycosis.  Methods: We studied 188 patients with paracoccidioidomycosis admitted to a tertiary referral hospital in the Central-West Region of Brazil from 2000 to 2010, to assess their compliance to treatment. In order to be considered compliant, patients needed to present two established criteria: (1) receive medicines from the pharmacy, and (2) achieve a self-reported utilization of at least 80% of the dispensed antifungal compounds prescribed since their previous appointment.  Results: Most patients were male (95.7%), had the chronic form of the disease (94.2%), and were treated with cotrimoxazole (86.2%). Only 44.6% of patients were treatment compliant. The highest loss to follow-up was observed in the first 4 months of treatment (p &lt; 0.02). Treatment compliance was higher for patients with than for those without pulmonary involvement (OR: 2.986; 95%CI 1.351-6.599), and higher for patients with than without tuberculosis as co-morbidity (OR: 2.763; 95%CI 1.004-7.604).  Conclusions: Compliance to paracoccidioidomycosis treatment was low, and the period with the highest loss to follow-up corresponds to the first four months. Pulmonary paracoccidioidal involvement or tuberculosis comorbidity predicts a higher compliance to paracoccidioidomycosis therapy.<\/jats:p>","DOI":"10.1590\/1806-3713\/e20180167","type":"journal-article","created":{"date-parts":[[2019,4,17]],"date-time":"2019-04-17T21:19:52Z","timestamp":1555535992000},"source":"Crossref","is-referenced-by-count":12,"title":["Treatment compliance of patients with paracoccidioidomycosis in Central-West Brazil"],"prefix":"10.1590","volume":"45","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6932-1692","authenticated-orcid":false,"given":"Ursulla Vilella","family":"Andrade","sequence":"first","affiliation":[{"name":"Universidade Federal de Mato Grosso do Sul,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8960-6716","authenticated-orcid":false,"given":"Sandra Maria do Valle Leone de","family":"Oliveira","sequence":"additional","affiliation":[{"name":"Universidade Federal de Mato Grosso do Sul,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3402-4740","authenticated-orcid":false,"given":"Marilene Rodrigues","family":"Chang","sequence":"additional","affiliation":[{"name":"Universidade Federal de Mato Grosso do Sul,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3011-6947","authenticated-orcid":false,"given":"Edy Firmina","family":"Pereira","sequence":"additional","affiliation":[{"name":"Universidade Federal de Mato Grosso do Sul,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4012-0720","authenticated-orcid":false,"given":"Ana Paula da Costa","family":"Marques","sequence":"additional","affiliation":[{"name":"Universidade Federal de Mato Grosso do Sul,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0575-2263","authenticated-orcid":false,"given":"Lidia Raquel de","family":"Carvalho","sequence":"additional","affiliation":[{"name":"Universidade Estadual de S\u00e3o Paulo,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0661-5917","authenticated-orcid":false,"given":"Rinaldo Poncio","family":"Mendes","sequence":"additional","affiliation":[{"name":"Universidade Estadual de S\u00e3o Paulo,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8925-7712","authenticated-orcid":false,"given":"Anamaria Mello Miranda","family":"Paniago","sequence":"additional","affiliation":[{"name":"Universidade Federal de Mato Grosso do Sul,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"530","published-online":{"date-parts":[[2019]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1590\/S0036-46652015000700004","article-title":"Epidemiology of 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