{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T03:37:58Z","timestamp":1792121878620,"version":"4.4.0"},"reference-count":30,"publisher":"FapUNIFESP (SciELO)","issue":"4","license":[{"start":{"date-parts":[[2021,4,1]],"date-time":"2021-04-01T00:00:00Z","timestamp":1617235200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2021,4,1]],"date-time":"2021-04-01T00:00:00Z","timestamp":1617235200000},"content-version":"am","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2021,4,1]],"date-time":"2021-04-01T00:00:00Z","timestamp":1617235200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rev. Assoc. Med. Bras."],"DOI":"10.1590\/1806-9282.20201005","type":"journal-article","created":{"date-parts":[[2021,9,6]],"date-time":"2021-09-06T15:09:13Z","timestamp":1630940953000},"page":"549-554","source":"Crossref","is-referenced-by-count":129,"title":["The association between serum uric acid to high density lipoprotein-cholesterol ratio and non-alcoholic fatty liver disease: the abund study"],"prefix":"10.1590","volume":"67","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3172-8200","authenticated-orcid":false,"given":"Mehmet Ali","family":"Kosekli","sequence":"first","affiliation":[{"name":"Abant Izzet Baysal University Hospital,  Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4162-5563","authenticated-orcid":false,"given":"Ozge","family":"Kurtkulagii","sequence":"additional","affiliation":[{"name":"Abant Izzet Baysal University Hospital,  Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4520-4085","authenticated-orcid":false,"given":"Gizem","family":"Kahveci","sequence":"additional","affiliation":[{"name":"Abant Izzet Baysal University Hospital,  Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3836-2125","authenticated-orcid":false,"given":"Tuba Taslamacioglu","family":"Duman","sequence":"additional","affiliation":[{"name":"Abant Izzet Baysal University Hospital,  Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4201-9757","authenticated-orcid":false,"given":"Burcin Meryem Atak","family":"Tel","sequence":"additional","affiliation":[{"name":"Abant Izzet Baysal University Hospital,  Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2811-0052","authenticated-orcid":false,"given":"Satilmis","family":"Bilgin","sequence":"additional","affiliation":[{"name":"Abant Izzet Baysal University Hospital,  Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6262-6103","authenticated-orcid":false,"given":"Muhammed Emin","family":"Demirkol","sequence":"additional","affiliation":[{"name":"Abant Izzet Baysal University Hospital,  Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7306-5233","authenticated-orcid":false,"given":"Gulali","family":"Aktas","sequence":"additional","affiliation":[{"name":"Abant Izzet Baysal University Hospital,  Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"530","published-online":{"date-parts":[[2021,4]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"837419","DOI":"10.1155\/2010\/837419","article-title":"Inflammatory mediators of hepatic steatosis","volume":"2010","author":"Hijona E","year":"2010","journal-title":"Mediators Inflamm"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"720","DOI":"10.1016\/j.jhep.2014.10.039","article-title":"Molecular mechanism of PPAR\u03b1 action and its impact on lipid metabolism, inflammation and fibrosis in non-alcoholic fatty liver disease","volume":"62","author":"Pawlak M","year":"2015","journal-title":"J Hepatol"},{"issue":"2","key":"ref3","doi-asserted-by":"crossref","first-page":"55","DOI":"10.30714\/j-ebr.2018237497","article-title":"Mean platelet volume to platelet ratio as a promising marker of hepatosteatosis","volume":"1","author":"Kosekli MA","year":"2018","journal-title":"Experimental Biomedical Research"},{"issue":"10","key":"ref4","doi-asserted-by":"crossref","first-page":"1354","DOI":"10.1111\/j.1464-5491.2005.01646.x","article-title":"Non-alcoholic hepatic steatosis and its relation to increased plasma biomarkers of inflammation and endothelial dysfunction in non-diabetic men. Role of visceral adipose tissue","volume":"22","author":"Targher G","year":"2005","journal-title":"Diabet Med"},{"issue":"3","key":"ref5","first-page":"264","article-title":"Mean platelet volume and red cell distribution width in hepatosteatosis","volume":"3","author":"Aktas G","year":"2013","journal-title":"Natl J Med Res"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"e1","DOI":"10.1097\/MEG.0000000000000486","article-title":"A novel model using mean platelet volume and neutrophil to lymphocyte ratio as a marker of nonalcoholic steatohepatitis in NAFLD patients: multicentric study","volume":"28","author":"Abdel-Razik A","year":"2016","journal-title":"Eur J Gastroenterol Hepatol"},{"issue":"9","key":"ref7","doi-asserted-by":"crossref","first-page":"1110","DOI":"10.1097\/MEG.0000000000001393","article-title":"Neutrophil-to-lymphocyte ratio is independently associated with inflammatory activity and fibrosis grade in nonalcoholic fatty liver disease","volume":"31","author":"Khoury T","year":"2019","journal-title":"Eur J Gastroenterol Hepatol"},{"issue":"6957","key":"ref8","doi-asserted-by":"crossref","first-page":"516","DOI":"10.1038\/nature01991","article-title":"Molecular identification of a danger signal that alerts the immune system to dying cells","volume":"425","author":"Shi Y","year":"2003","journal-title":"Nature"},{"issue":"3","key":"ref9","first-page":"E107","article-title":"Reduction of serum uric acid associated with attenuation of renal injury, inflammation and macrophages m1\/m2 ratio in hyperuricemic mice model","volume":"64","author":"Haryono A","year":"2018","journal-title":"Kobe J Med Sci"},{"issue":"6","key":"ref10","doi-asserted-by":"crossref","first-page":"e0179482","DOI":"10.1371\/journal.pone.0179482","article-title":"The association between serum uric acid and the incidence of prediabetes and type 2 diabetes mellitus: the rotterdam study","volume":"12","author":"van der Schaft N","year":"2017","journal-title":"PLoS One"},{"issue":"11","key":"ref11","doi-asserted-by":"crossref","first-page":"e0206850","DOI":"10.1371\/journal.pone.0206850","article-title":"Prevalence of hyperuricemia and the relationship between serum uric acid and obesity: A study on Bangladeshi adults","volume":"13","author":"Ali N","year":"2018","journal-title":"PLoS One"},{"issue":"48","key":"ref12","doi-asserted-by":"crossref","first-page":"e307","DOI":"10.3346\/jkms.2019.34.e307","article-title":"Association between Serum Uric Acid and Metabolic Syndrome in Koreans","volume":"34","author":"Jeong J","year":"2019","journal-title":"J Korean Med Sci"},{"issue":"1","key":"ref13","doi-asserted-by":"crossref","first-page":"6","DOI":"10.30714\/j-ebr.2018136918","article-title":"Serum uric acid is correlated with HbA1c levels in type 2 diabetes mellitus","volume":"1","author":"Duman TT","year":"2018","journal-title":"Exp Biomed Res"},{"issue":"4","key":"ref14","first-page":"135","article-title":"Serum uric acid level is associated with type 2 diabetes mellitus and diabetic regulation","volume":"1","author":"Atak BM","year":"2018","journal-title":"Exp Biomed Res"},{"issue":"2","key":"ref15","first-page":"136","article-title":"Association between Serum Uric Acid and Non-Alcoholic Fatty Liver Disease: A Meta-Analysis","volume":"49","author":"Darmawan G","year":"2017","journal-title":"Acta Med Indones"},{"issue":"1","key":"ref16","first-page":"64","article-title":"Association of non-alcoholic fatty liver disease with serum uric acid","volume":"31","author":"Abbasi S","year":"2019","journal-title":"j ayub med coll abbottabad"},{"issue":"1","key":"ref17","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1186\/s12944-017-0531-5","article-title":"Serum uric acid and non-alcoholic fatty liver disease in non-obesity Chinese adults","volume":"16","author":"Zheng X","year":"2017","journal-title":"Lipids Health Dis"},{"issue":"48","key":"ref18","doi-asserted-by":"crossref","first-page":"40732","DOI":"10.1074\/jbc.M112.399899","article-title":"Uric acid induces hepatic steatosis by generation of mitochondrial oxidative stress: potential role in fructose-dependent and -independent fatty liver","volume":"287","author":"Lanaspa MA","year":"2012","journal-title":"J Biol Chem"},{"issue":"1","key":"ref19","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1590\/1806-9282.65.1.9","article-title":"Serum uric acid to HDL-cholesterol ratio is a strong predictor of metabolic syndrome in type 2 diabetes mellitus","volume":"65","author":"Kocak MZ","year":"2019","journal-title":"Rev Assoc Med Bras (1992)"},{"issue":"5","key":"ref20","doi-asserted-by":"crossref","first-page":"1098","DOI":"10.1080\/13685538.2019.1678126","article-title":"Uric acid to HDL cholesterol ratio is a strong predictor of diabetic control in men with type 2 diabetes mellitus","volume":"23","author":"Aktas G","year":"2020","journal-title":"Aging Male"},{"issue":"12","key":"ref21","doi-asserted-by":"crossref","first-page":"2771","DOI":"10.5455\/annalsmedres.2019.08.479","article-title":"Serum uric acid and uric acid to HDL-cholesterol ratio in coronary artery fistulas","volume":"26","author":"Mansiroglu AK","year":"2019","journal-title":"Annals of Medical Research"},{"key":"ref22","doi-asserted-by":"crossref","first-page":"5953461","DOI":"10.1155\/2020\/5953461","article-title":"Association between serum uric acid to hdl-cholesterol ratio and nonalcoholic fatty liver disease in lean chinese adults","volume":"2020","author":"Zhang YN","year":"2020","journal-title":"Int J Endocrinol"},{"issue":"9","key":"ref23","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1007\/s11906-017-0770-x","article-title":"Hyperuricemia, type 2 diabetes mellitus, and hypertension: an emerging association","volume":"19","author":"Mortada I","year":"2017","journal-title":"Curr Hypertens Rep"},{"issue":"6","key":"ref24","doi-asserted-by":"crossref","first-page":"1120","DOI":"10.2337\/dc18-2147","article-title":"Elevated serum uric acid is associated with greater risk for hypertension and diabetic kidney diseases in obese adolescents with type 2 diabetes: an observational analysis from the treatment options for type 2 diabetes in adolescents and youth (TODAY) study","volume":"42","author":"Bjornstad P","year":"2019","journal-title":"Diabetes Care"},{"issue":"27","key":"ref25","doi-asserted-by":"crossref","first-page":"4930","DOI":"10.2174\/1381612811319270016","article-title":"Uric acid and diabetes: Is there a link?","volume":"19","author":"Katsiki N","year":"2013","journal-title":"Curr Pharm Des"},{"issue":"10","key":"ref26","doi-asserted-by":"crossref","first-page":"e78206","DOI":"10.1371\/journal.pone.0078206","article-title":"Hyperuricemia as an independent predictor of vascular complications and mortality in type 2 diabetes patients: a meta-analysis","volume":"8","author":"Xu Y","year":"2013","journal-title":"PLoS One"},{"issue":"11","key":"ref27","doi-asserted-by":"crossref","first-page":"1000","DOI":"10.1016\/j.jdiacomp.2018.09.002","article-title":"Interactive effect of serum uric acid and total bilirubin for micro-vascular disease of type 2 diabetes in China","volume":"32","author":"Ren Y","year":"2018","journal-title":"J Diabetes Complications"},{"issue":"3","key":"ref28","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1089\/met.2013.0075","article-title":"Metabolic syndrome in Turner syndrome and relation between body composition and clinical, genetic, and ultrasonographic characteristics","volume":"12","author":"Calcaterra V","year":"2014","journal-title":"Metab Syndr Relat Disord"},{"issue":"7","key":"ref29","first-page":"528","article-title":"[The application of proton magnetic resonance spectroscopy and computerized tomography in evaluating nonalcoholic fatty liver disease]","volume":"16","author":"Wang N","year":"2008","journal-title":"Chinese"},{"key":"ref30","doi-asserted-by":"crossref","first-page":"S77","DOI":"10.1016\/j.dsx.2016.01.034","article-title":"Correlation between non-alcoholic fatty liver disease (NAFLD) and dyslipidemia in type 2 diabetes","volume":"10","author":"Krishan S","year":"2016","journal-title":"Diabetes Metab Syndr"}],"container-title":["Revista da Associa\u00e7\u00e3o M\u00e9dica Brasileira"],"original-title":[],"link":[{"URL":"http:\/\/www.scielo.br\/pdf\/ramb\/v67n4\/1806-9282-ramb-67-04-0549.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,9,6]],"date-time":"2021-09-06T15:09:39Z","timestamp":1630940979000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.scielo.br\/scielo.php?script=sci_arttext&pid=S0104-42302021000500549&tlng=en"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,4]]},"references-count":30,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2021,4]]}},"alternative-id":["S0104-42302021000500549"],"URL":"https:\/\/doi.org\/10.1590\/1806-9282.20201005","relation":{},"ISSN":["1806-9282","0104-4230"],"issn-type":[{"value":"1806-9282","type":"electronic"},{"value":"0104-4230","type":"print"}],"subject":[],"published":{"date-parts":[[2021,4]]}}}