{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T15:08:05Z","timestamp":1753888085520,"version":"3.41.2"},"reference-count":14,"publisher":"FapUNIFESP (SciELO)","issue":"12","license":[{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"am","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rev. Assoc. Med. Bras."],"DOI":"10.1590\/1806-9282.20230680","type":"journal-article","created":{"date-parts":[[2023,11,13]],"date-time":"2023-11-13T11:02:25Z","timestamp":1699873345000},"source":"Crossref","is-referenced-by-count":0,"title":["Evaluation of the relationship between toxicity of cyclin-dependent kinase 4\/6 inhibitors and body surface area"],"prefix":"10.1590","volume":"69","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5869-0679","authenticated-orcid":false,"given":"\u015eafak Yildirim","family":"Di\u015fli","sequence":"first","affiliation":[{"name":"Kayseri City Hospital,  Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6338-5564","authenticated-orcid":false,"given":"Evren","family":"Fidan","sequence":"additional","affiliation":[{"name":"Karadeniz Technical University,  Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"530","published-online":{"date-parts":[[2023]]},"reference":[{"issue":"1","key":"ref1","doi-asserted-by":"crossref","first-page":"7","DOI":"10.3322\/caac.21654","article-title":"Cancer statistics, 2021","volume":"71","author":"Siegel RL","year":"2021","journal-title":"CA Cancer J Clin"},{"issue":"2","key":"ref2","article-title":"Chemotherapy alone versus endocrine therapy alone for metastatic breast cancer","volume":"2003","author":"Wilcken N","year":"2003","journal-title":"Cochrane Database Syst Rev"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"658","DOI":"10.1177\/1947601913478972","article-title":"CDK4: a key player in the cell cycle, development, and cancer","volume":"3","author":"Baker SJ","year":"2012","journal-title":"Genes Cancer"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"4","DOI":"10.3389\/fonc.2013.00004","article-title":"Re-thinking cell cycle regulators: the cross-talk with metabolism","volume":"3","author":"Fajas L","year":"2013","journal-title":"Front Oncol"},{"issue":"1","key":"ref5","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1172\/JCI81480","article-title":"CDK4 is an essential insulin effector in adipocytes","volume":"126","author":"Lagarrigue S","year":"2016","journal-title":"J Clin Invest"},{"issue":"4","key":"ref6","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1016\/j.cmet.2005.09.003","article-title":"Cdk4 promotes adipogenesis through PPARgamma activation","volume":"2","author":"Abella A","year":"2005","journal-title":"Cell Metab"},{"issue":"17","key":"ref7","doi-asserted-by":"crossref","DOI":"10.1172\/jci.insight.123000","article-title":"Cyclin-dependent kinase 4 is a preclinical target for diet-induced obesity","volume":"3","author":"Iqbal NJ","year":"2018","journal-title":"JCI Insight"},{"issue":"10","key":"ref8","doi-asserted-by":"crossref","first-page":"1901","DOI":"10.1093\/annonc\/mdu042","article-title":"Body mass index and survival in women with breast cancer-systematic literature review and meta-analysis of 82 follow-up studies","volume":"25","author":"Chan DSM","year":"2014","journal-title":"Ann Oncol"},{"issue":"6","key":"ref9","doi-asserted-by":"crossref","first-page":"875","DOI":"10.1093\/annonc\/mdh222","article-title":"Body mass index as a prognostic feature in operable breast cancer: the international breast cancer study group experience","volume":"15","author":"Berclaz G","year":"2004","journal-title":"Ann Oncol"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1007\/978-1-62703-758-7_17","article-title":"Sources of interindividual variability","volume":"1113","author":"Thummel KE","year":"2014","journal-title":"Methods Mol Biol"},{"issue":"18","key":"ref11","doi-asserted-by":"crossref","first-page":"2037","DOI":"10.1200\/JCO.21.00471","article-title":"Appropriate systemic therapy dosing for obese adult patients with cancer: ASCO guideline update","volume":"39","author":"Griggs JJ","year":"2021","journal-title":"J Clin Oncol"},{"issue":"5","key":"ref12","doi-asserted-by":"crossref","first-page":"679","DOI":"10.1038\/s41416-021-01415-9","article-title":"Safety and impact of dose reductions on efficacy in the randomised MONALEESA-2, \u22123 and \u22127 trials in hormone receptor-positive, HER2-negative advanced breast cancer","volume":"125","author":"Burris HA","year":"2021","journal-title":"Br J Cancer"},{"issue":"4","key":"ref13","doi-asserted-by":"crossref","first-page":"462","DOI":"10.1093\/jnci\/djaa116","article-title":"Clinical implications of body mass index in metastatic breast cancer patients treated with abemaciclib and endocrine therapy","volume":"113","author":"Franzoi MA","year":"2021","journal-title":"J Natl Cancer Inst"},{"issue":"7","key":"ref14","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0253722","article-title":"Efficacy and safety of palbociclib and ribociclib in patients with estrogen and\/or progesterone receptor positive, HER2 receptor negative metastatic breast cancer in routine clinical practice","volume":"16","author":"Rath S","year":"2021","journal-title":"PLoS One"}],"container-title":["Revista da Associa\u00e7\u00e3o M\u00e9dica Brasileira"],"original-title":[],"link":[{"URL":"http:\/\/www.scielo.br\/scielo.php?script=sci_pdf&pid=S0104-42302023001200612&tlng=en","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,13]],"date-time":"2023-11-13T11:02:33Z","timestamp":1699873353000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.scielo.br\/scielo.php?script=sci_arttext&pid=S0104-42302023001200612&tlng=en"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023]]},"references-count":14,"journal-issue":{"issue":"12","published-online":{"date-parts":[[2023]]}},"alternative-id":["S0104-42302023001200612"],"URL":"https:\/\/doi.org\/10.1590\/1806-9282.20230680","relation":{},"ISSN":["1806-9282","0104-4230"],"issn-type":[{"type":"electronic","value":"1806-9282"},{"type":"print","value":"0104-4230"}],"subject":[],"published":{"date-parts":[[2023]]},"article-number":"e20230680"}}