{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,19]],"date-time":"2026-04-19T19:11:25Z","timestamp":1776625885393,"version":"3.51.2"},"reference-count":17,"publisher":"FapUNIFESP (SciELO)","issue":"3","license":[{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"am","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rev. Assoc. Med. Bras."],"abstract":"<jats:p>SUMMARY  OBJECTIVE: In our study, we aimed to compare the effect of standard rapid sequence intubation protocol and the application of rocuronium priming technique on the procedure time and hemodynamic profile.  METHODS: Patients who applied to the emergency department and needed rapid sequence intubation were included in our study, which we conducted with a randomized controlled design. Randomization in the study was made according to the order of arrival of the cases. Rapid sequence intubation was performed in the standard group. In the priming group, 10% of the rocuronium dose was administered approximately 3 min before the induction agent. Intubation time, amount of drug used, vital signs, and end-tidal CO2 level before and after intubation used to confirm intubation were recorded.  RESULTS: A total of 52 patients were included in the study, of which 26 patients were included in the standard group and 26 patients in the priming group. While intubation time was 121.2\u00b121.9 s in the standard group, it was calculated as 68.4\u00b111.6 s in the priming group (p&lt;0.001). While the mean arterial pressure was 58.3\u00b126.6 mmHg in the standard group after intubation, it was 80.6\u00b121.1 mmHg in the priming group (p=0.002).  CONCLUSION: It was observed that priming with rocuronium shortened the intubation time and preserved the hemodynamic profile better.  Clinical Trial Registration Number: NCT05343702.<\/jats:p>","DOI":"10.1590\/1806-9282.20231029","type":"journal-article","created":{"date-parts":[[2025,6,10]],"date-time":"2025-06-10T12:33:42Z","timestamp":1749558822000},"source":"Crossref","is-referenced-by-count":1,"title":["Comparison of rocuronium priming vs. standard rapid sequence intubation technique in emergency department patients requiring intubation"],"prefix":"10.1590","volume":"70","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3802-3502","authenticated-orcid":false,"given":"Nurullah \u0130shak","family":"I\u015f\u0131k","sequence":"first","affiliation":[{"name":"Ankara Etlik City Hospital,  Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2707-4099","authenticated-orcid":false,"given":"Ayhan","family":"\u00d6zhasenekler","sequence":"additional","affiliation":[{"name":"Ankara Bilkent City Hospital,  Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7456-5395","authenticated-orcid":false,"given":"\u00c7a\u011fda\u015f","family":"Y\u0131ld\u0131r\u0131m","sequence":"additional","affiliation":[{"name":"Ankara Bilkent City Hospital,  Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0583-2936","authenticated-orcid":false,"given":"Alp","family":"\u015eener","sequence":"additional","affiliation":[{"name":"Ankara Bilkent City Hospital,  Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8002-0404","authenticated-orcid":false,"given":"Fatih Ahmet","family":"Kahraman","sequence":"additional","affiliation":[{"name":"Ankara Bilkent City Hospital,  Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8531-4591","authenticated-orcid":false,"given":"G\u00fcl Pamuk\u00e7u","family":"G\u00fcnayd\u0131n","sequence":"additional","affiliation":[{"name":"Ankara Bilkent City Hospital,  Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"530","published-online":{"date-parts":[[2024]]},"reference":[{"issue":"12","key":"ref1","doi-asserted-by":"crossref","first-page":"484","DOI":"10.1016\/j.bjae.2022.09.001","article-title":"Rapid sequence induction and intubation","volume":"22","author":"Collins J","year":"2022","journal-title":"BJA Educ"},{"issue":"4","key":"ref2","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1016\/j.jemermed.2010.02.024","article-title":"NEAR II Investigators. Emergency airway management: a multi-center report of 8937 emergency department intubations","volume":"41","author":"Walls RM","year":"2011","journal-title":"J Emerg Med"},{"issue":"3","key":"ref3","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1177\/0885066607299525","article-title":"Complications of emergency tracheal intubation: hemodynamic alterations--part I","volume":"22","author":"Mort TC","year":"2007","journal-title":"J Intensive Care Med"},{"issue":"4","key":"ref4","doi-asserted-by":"crossref","first-page":"417.e9","DOI":"10.1016\/j.jcrc.2011.08.011","article-title":"The frequency and significance of postintubation hypotension during emergency airway management","volume":"27","author":"Heffner AC","year":"2012","journal-title":"J Crit Care"},{"issue":"3","key":"ref5","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1016\/j.annemergmed.2017.04.039","article-title":"Rocuronium should be the default paralytic in rapid sequence 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\u00e7alisma","volume":"32","author":"G\u00fcra, M","year":"2012","journal-title":"T\u00fcrkiye Klinikleri Tip Bilimleri Dergisi"},{"issue":"5","key":"ref12","first-page":"500","article-title":"Factors that affect the onset of action of non-depolarizing neuromuscular blocking agents","volume":"70","author":"Kim YB","year":"2017","journal-title":"[Erratum in: Korean J Anesthesiol"},{"issue":"5","key":"ref13","doi-asserted-by":"crossref","first-page":"494","DOI":"10.4103\/0019-5049.89882","article-title":"Comparison of intubating conditions between rocuronium with priming and without priming: randomized and double-blind study","volume":"55","author":"Rao MH","year":"2011","journal-title":"Indian J Anaesth"},{"issue":"7","key":"ref14","doi-asserted-by":"crossref","first-page":"748","DOI":"10.1111\/j.1365-2044.2012.07102.x","article-title":"A randomised controlled trial comparing rocuronium priming, magnesium pre-treatment and a combination of the two methods","volume":"67","author":"Kim MH","year":"2012","journal-title":"Anaesthesia"},{"issue":"3","key":"ref15","doi-asserted-by":"crossref","first-page":"663","DOI":"10.1213\/00000539-199709000-00032","article-title":"The effect of priming with vecuronium and rocuronium on young and elderly patients","volume":"85","author":"Aziz L","year":"1997","journal-title":"Anesth Analg"},{"key":"ref16","series-title":"StatPearls","volume-title":"Rocuronium","author":"Jain A","year":"2023"},{"issue":"2","key":"ref17","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1007\/s10877-021-00653-9","article-title":"Mechanisms contributing to hypotension after anesthetic induction with sufentanil, propofol, and rocuronium: a prospective observational study","volume":"36","author":"Saugel B","year":"2022","journal-title":"J Clin Monit Comput"}],"container-title":["Revista da Associa\u00e7\u00e3o M\u00e9dica 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