{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T01:19:51Z","timestamp":1788830391845,"version":"build-2803163510"},"reference-count":15,"publisher":"FapUNIFESP (SciELO)","issue":"4","license":[{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"am","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rev. Assoc. Med. Bras."],"DOI":"10.1590\/1806-9282.20231521","type":"journal-article","created":{"date-parts":[[2024,5,3]],"date-time":"2024-05-03T10:30:22Z","timestamp":1714732222000},"source":"Crossref","is-referenced-by-count":2,"title":["Reduced expression of miRNAs as potential biomarkers in axial spondyloarthritis"],"prefix":"10.1590","volume":"70","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8613-5373","authenticated-orcid":false,"given":"Nurdan Oru\u00e7o\u011flu","family":"Y\u0131ld\u0131r\u0131m","sequence":"first","affiliation":[{"name":"Mersin University,  Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7498-604X","authenticated-orcid":false,"given":"\u015eenay","family":"Balc\u0131","sequence":"additional","affiliation":[{"name":"Mersin University,  Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0997-0260","authenticated-orcid":false,"given":"L\u00fcl\u00fcfer","family":"Tamer","sequence":"additional","affiliation":[{"name":"Mersin University,  Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"530","published-online":{"date-parts":[[2024]]},"reference":[{"issue":"1","key":"ref1","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1038\/s41413-019-0057-8","article-title":"Ankylosing spondylitis: etiology, pathogenesis, and treatments","volume":"7","author":"Zhu W","year":"2019","journal-title":"Bone Res"},{"key":"ref2","article-title":"The potential role of genetics, environmental factors, and gut dysbiosis in the aberrant non-coding RNA expression to mediate inflammation and osteoclastogenic\/osteogenic differentiation in ankylosing spondylitis","volume":"9","author":"Liao HT","year":"2022","journal-title":"Front Cell Dev Biol"},{"key":"ref3","doi-asserted-by":"crossref","DOI":"10.1016\/j.jtauto.2020.100050","article-title":"MicroRNAs in ankylosing spondylitis: function, potential and challenges","volume":"3","author":"Motta F","year":"2020","journal-title":"J Transl Autoimmun"},{"issue":"9","key":"ref4","doi-asserted-by":"crossref","first-page":"1415","DOI":"10.1002\/acr.21688","article-title":"Do patients with non-radiographic axial spondylarthritis differ from patients with ankylosing spondylitis?","volume":"64","author":"Kiltz U","year":"2012","journal-title":"Arthritis Care Res (Hoboken)"},{"issue":"7","key":"ref5","doi-asserted-by":"crossref","first-page":"1188","DOI":"10.1111\/1756-185X.13563","article-title":"Aberrant expression of microRNAs in peripheral blood mononuclear cells as candidate biomarkers in patients with axial spondyloarthritis","volume":"22","author":"Li X","year":"2019","journal-title":"Int J Rheum Dis"},{"issue":"4","key":"ref6","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1006\/meth.2001.1262","article-title":"Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method","volume":"25","author":"Livak KJ","year":"2001","journal-title":"Methods"},{"issue":"8","key":"ref7","doi-asserted-by":"crossref","first-page":"5564","DOI":"10.1002\/jcp.26500","article-title":"MicroRNA implications in the etiopathogenesis of ankylosing spondylitis","volume":"233","author":"Mohammadi H","year":"2018","journal-title":"J Cell Physiol"},{"issue":"3","key":"ref8","doi-asserted-by":"crossref","first-page":"717","DOI":"10.1002\/art.24483","article-title":"The early disease stage in axial spondylarthritis: results from the German spondyloarthritis inception cohort","volume":"60","author":"Rudwaleit M","year":"2009","journal-title":"Arthritis Rheum"},{"issue":"5","key":"ref9","doi-asserted-by":"crossref","first-page":"469","DOI":"10.3109\/s10165-009-0211-z","article-title":"Screening tests for inflammatory activity: applications in rheumatology","volume":"19","author":"Rosa NS","year":"2009","journal-title":"Mod Rheumatol"},{"issue":"12","key":"ref10","doi-asserted-by":"crossref","first-page":"861","DOI":"10.1038\/nrg3074","article-title":"Non-coding RNAs in human disease","volume":"12","author":"Esteller M","year":"2011","journal-title":"Nat Rev Genet"},{"issue":"3","key":"ref11","doi-asserted-by":"crossref","first-page":"620","DOI":"10.1136\/annrheumdis-2016-210175","article-title":"miR-10b-5p is a novel Th17 regulator present in Th17 cells from ankylosing spondylitis","volume":"76","author":"Chen L","year":"2017","journal-title":"Ann Rheum Dis"},{"issue":"1","key":"ref12","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1186\/s13075-019-1829-7","article-title":"Deregulation of microRNA expression in monocytes and CD4+ T lymphocytes from patients with axial spondyloarthritis","volume":"21","author":"Fogel O","year":"2019","journal-title":"Arthritis Res Ther"},{"issue":"9","key":"ref13","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0185323","article-title":"Association between circulating miRNAs and spinal involvement in patients with axial spondyloarthritis","volume":"12","author":"Prajzlerov\u00e1 K","year":"2017","journal-title":"PLoS One"},{"issue":"1","key":"ref14","doi-asserted-by":"crossref","first-page":"35","DOI":"10.3892\/mmr.2015.4494","article-title":"Role of histone deacetylase 3 in ankylosing spondylitis via negative feedback loop with microRNA-130a and enhancement of tumor necrosis factor-1\u03b1 expression in peripheral blood mononuclear cells","volume":"13","author":"Jiang Y","year":"2016","journal-title":"Mol Med Rep"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1016\/j.gene.2019.02.004","article-title":"MiRNA as biomarker for uveitis - a systematic review of the literature","volume":"696","author":"Pockar S","year":"2019","journal-title":"Gene"}],"container-title":["Revista da Associa\u00e7\u00e3o M\u00e9dica Brasileira"],"original-title":[],"link":[{"URL":"http:\/\/www.scielo.br\/scielo.php?script=sci_pdf&pid=S0104-42302024000400620&tlng=en","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,3]],"date-time":"2024-05-03T10:30:32Z","timestamp":1714732232000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.scielo.br\/scielo.php?script=sci_arttext&pid=S0104-42302024000400620&tlng=en"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024]]},"references-count":15,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2024]]}},"alternative-id":["S0104-42302024000400620"],"URL":"https:\/\/doi.org\/10.1590\/1806-9282.20231521","relation":{},"ISSN":["1806-9282","0104-4230"],"issn-type":[{"value":"1806-9282","type":"electronic"},{"value":"0104-4230","type":"print"}],"subject":[],"published":{"date-parts":[[2024]]},"article-number":"e20231521"}}