{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,25]],"date-time":"2026-03-25T14:45:14Z","timestamp":1774449914501,"version":"3.50.1"},"reference-count":18,"publisher":"FapUNIFESP (SciELO)","issue":"12","license":[{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"am","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rev. Assoc. Med. Bras."],"DOI":"10.1590\/1806-9282.20240861","type":"journal-article","created":{"date-parts":[[2024,12,2]],"date-time":"2024-12-02T12:32:50Z","timestamp":1733142770000},"source":"Crossref","is-referenced-by-count":1,"title":["Comparison of the effectiveness of nebulizer treatment applications in acute exacerbation of chronic obstructive pulmonary disease: a randomized controlled trial"],"prefix":"10.1590","volume":"70","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6048-1462","authenticated-orcid":false,"given":"Bu\u011fra","family":"Kerget","sequence":"first","affiliation":[{"name":"Ataturk University,  Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-6425-1544","authenticated-orcid":false,"given":"Erdal","family":"Tekin","sequence":"additional","affiliation":[{"name":"Ataturk University,  Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-9882-3771","authenticated-orcid":false,"given":"Gizem","family":"\u00c7il","sequence":"additional","affiliation":[{"name":"Ataturk University,  Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-8488-6753","authenticated-orcid":false,"given":"Kadir","family":"\u00c7elik","sequence":"additional","affiliation":[{"name":"Ataturk University,  Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6883-3314","authenticated-orcid":false,"given":"Alperen","family":"Aksakal","sequence":"additional","affiliation":[{"name":"Ataturk University,  Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"530","published-online":{"date-parts":[[2024]]},"reference":[{"issue":"1","key":"ref1","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1016\/S2213-2600(22)00494-5","article-title":"GOLD COPD report: 2023 update","volume":"11","author":"Venkatesan P","year":"2023","journal-title":"Lancet Respir Med"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"745","DOI":"10.2147\/COPD.S404690","article-title":"GOLD 2023 update: implications for clinical practice","volume":"18","author":"Tamondong-Lachica DR","year":"2023","journal-title":"Int J Chron Obstruct Pulmon Dis"},{"issue":"11","key":"ref3","doi-asserted-by":"crossref","first-page":"1317","DOI":"10.1164\/rccm.202204-0671PP","article-title":"Definition and nomenclature of chronic obstructive pulmonary disease: time for its revision","volume":"206","author":"Celli B","year":"2022","journal-title":"Am J Respir Crit Care Med"},{"issue":"7","key":"ref4","doi-asserted-by":"crossref","first-page":"819","DOI":"10.1164\/rccm.202301-0106PP","article-title":"Global initiative for chronic obstructive lung disease 2023 report: GOLD executive summary","volume":"207","author":"Agust\u00ed A","year":"2023","journal-title":"Am J Respir Crit Care Med"},{"issue":"6","key":"ref5","doi-asserted-by":"crossref","first-page":"532","DOI":"10.1164\/rccm.200703-456SO","article-title":"Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease: GOLD executive summary","volume":"176","author":"Rabe KF","year":"2007","journal-title":"Am J Respir Crit Care Med"},{"issue":"Suppl 2","key":"ref6","doi-asserted-by":"crossref","first-page":"S25","DOI":"10.1136\/thx.52.2008.S25","article-title":"Overview of nebuliser treatment","volume":"52","author":"Muers MF","year":"1997","journal-title":"Thorax"},{"issue":"3","key":"ref7","doi-asserted-by":"crossref","first-page":"2301335","DOI":"10.1183\/13993003.01335-2023","article-title":"GOLD 2023 streamlines pharmacological treatment","volume":"62","author":"Singh D","year":"2023","journal-title":"Eur Respir J"},{"issue":"8","key":"ref8","doi-asserted-by":"crossref","first-page":"e70","DOI":"10.1164\/rccm.201908-1590ST","article-title":"Standardization of spirometry 2019 update. An Official American Thoracic Society and European Respiratory Society Technical Statement","volume":"200","author":"Graham BL","year":"2019","journal-title":"Am J Respir Crit Care Med"},{"issue":"1","key":"ref9","doi-asserted-by":"crossref","first-page":"58","DOI":"10.3109\/15412555.2011.630047","article-title":"The role of nebulized therapy in the management of COPD: evidence and recommendations","volume":"9","author":"Dhand R","year":"2012","journal-title":"COPD"},{"issue":"Suppl 2","key":"ref10","doi-asserted-by":"crossref","first-page":"S49","DOI":"10.1136\/thx.52.2008.S49","article-title":"Nebulisers for chronic obstructive pulmonary disease","volume":"52","author":"O\u2019Driscoll BR","year":"1997","journal-title":"Thorax"},{"issue":"76","key":"ref11","first-page":"511","article-title":"Nebulizers in acute exacerbations of chronic obstructive pulmonary disease.","volume":"10","author":"Muers M","year":"2000","journal-title":"Eur Respiratory Rev"},{"issue":"5 Suppl","key":"ref12","first-page":"S139","article-title":"An assessment of therapeutic regimens in the treatment of acute exacerbations in chronic obstructive pulmonary disease and asthma","volume":"10","author":"Skrepnek GH","year":"2004","journal-title":"Am J Manag Care"},{"key":"ref13","doi-asserted-by":"crossref","first-page":"1665","DOI":"10.2147\/COPD.S252435","article-title":"Nebulized therapies in COPD: past, present, and the future","volume":"15","author":"Barjaktarevic IZ","year":"2020","journal-title":"Int J Chron Obstruct Pulmon Dis"},{"issue":"1","key":"ref14","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1177\/17511437231199899","article-title":"Nebuliser therapy in critical care: the past, present and future","volume":"25","author":"Arnott A","year":"2024","journal-title":"J Intensive Care Soc"},{"issue":"5","key":"ref15","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1186\/cc11475","article-title":"Oxygen-induced hypercapnia in COPD: myths and facts","volume":"16","author":"Abdo WF","year":"2012","journal-title":"Crit Care"},{"issue":"2","key":"ref16","first-page":"158","article-title":"Practical problems with aerosol therapy in COPD.","volume":"51","author":"Rau JL","year":"2006","journal-title":"Respir Care"},{"key":"ref17","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1016\/j.rmed.2019.05.016","article-title":"A mesh nebulizer is more effective than jet nebulizer to nebulize bronchodilators during non-invasive ventilation of subjects with COPD: a randomized controlled trial with radiolabeled aerosols","volume":"153","author":"Galindo Filho VC","year":"2019","journal-title":"Respir Med"},{"issue":"3","key":"ref18","doi-asserted-by":"crossref","first-page":"653","DOI":"10.1016\/j.chest.2023.11.013","article-title":"Guidance on mitigating the risk of transmitting respiratory infections during nebulization by the COPD foundation nebulizer consortium","volume":"165","author":"Biney IN","year":"2024","journal-title":"Chest"}],"container-title":["Revista da Associa\u00e7\u00e3o M\u00e9dica Brasileira"],"original-title":[],"link":[{"URL":"http:\/\/www.scielo.br\/scielo.php?script=sci_pdf&pid=S0104-42302024001200616&tlng=en","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,12,2]],"date-time":"2024-12-02T12:32:56Z","timestamp":1733142776000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.scielo.br\/scielo.php?script=sci_arttext&pid=S0104-42302024001200616&tlng=en"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024]]},"references-count":18,"journal-issue":{"issue":"12","published-online":{"date-parts":[[2024]]}},"alternative-id":["S0104-42302024001200616"],"URL":"https:\/\/doi.org\/10.1590\/1806-9282.20240861","relation":{},"ISSN":["1806-9282","0104-4230"],"issn-type":[{"value":"1806-9282","type":"electronic"},{"value":"0104-4230","type":"print"}],"subject":[],"published":{"date-parts":[[2024]]},"article-number":"e20240861"}}