{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T05:06:38Z","timestamp":1782968798362,"version":"3.54.5"},"reference-count":25,"publisher":"FapUNIFESP (SciELO)","issue":"6","license":[{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"am","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rev. Assoc. Med. Bras."],"abstract":"<jats:p>SUMMARY  OBJECTIVE: The objective of this study was to compare anthropometric data and pulmonary and extrapulmonary physical functional outcomes of short- and long-term use of inhaled corticosteroids in adults with asthma.  METHODS: This cross-sectional study with retrospective analysis included clinically stable adults with asthma. Anthropometric data, exacerbation history, pulmonary function, disease control, dyspnea in daily life, quality of life, anxiety, depression, functional exercise capacity, performance in daily activities, body composition, physical activity level, respiratory muscle strength, lower limb strength, and handgrip strength were assessed and compared. Participants were separated into two groups based on the current duration of inhaled corticosteroids use below (short-term) or above (long-term) 3 years (\u22643 years [n=37] and &gt;3 years [n=30]) for comparative analysis.  RESULTS: A total of 67 participants were analyzed (69% female, 49\u00b114 years, body mass index 29\u00b16 kg\/m\u00b2, FEV1 2.21\u00b10.79 L). The group \u22643 years presented statistically higher spirometric values and exercise capacity compared to the group &gt;3 years even after analysis of covariance adjustments for age, body mass index, disease control, and treatment duration (forced vital capacity 3.39 [3.09\u20133.70] L vs. 2.93 [2.59\u20133.26] L, p=0.048; FEV1 2.40 [2.17\u20132.63] L vs. 2.00 [1.75\u20132.25] L, p=0.023; 6-min walk test 567 [536\u2013599] vs. 519 [484\u2013554] m, respectively, p=0.048). All the other variables were similar between groups (p&gt;0.05 for all).  CONCLUSION: Participants who used inhaled corticosteroids for more than 3 years exhibited worse pulmonary function and exercise capacity. Despite this, exacerbation history, disease control, quality of life, anxiety, depression, and dyspnea in daily life, among other physical functional outcomes, were similar between short- and long-term use of inhaled corticosteroids in adults with asthma.<\/jats:p>","DOI":"10.1590\/1806-9282.20241240","type":"journal-article","created":{"date-parts":[[2025,7,8]],"date-time":"2025-07-08T13:59:59Z","timestamp":1751983199000},"source":"Crossref","is-referenced-by-count":1,"title":["Associations with short-term and long-term use of inhaled corticosteroid in adults with asthma. A retrospective analysis"],"prefix":"10.1590","volume":"71","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6192-6734","authenticated-orcid":false,"given":"Ariele","family":"Pedroso","sequence":"first","affiliation":[{"name":"Universidade Pit\u00e1goras Unopar Anhanguera,  Brazil; Universidade Estadual de Londrina,  Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3387-2940","authenticated-orcid":false,"given":"Joice Mara de","family":"Oliveira","sequence":"additional","affiliation":[{"name":"Universidade Pit\u00e1goras Unopar Anhanguera,  Brazil; Universidade Estadual de Londrina,  Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9814-9377","authenticated-orcid":false,"given":"Thain\u00e1 Bessa","family":"Alves","sequence":"additional","affiliation":[{"name":"Universidade Pit\u00e1goras Unopar Anhanguera,  Brazil; Universidade Estadual de Londrina,  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Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4169-5262","authenticated-orcid":false,"given":"Marcos","family":"Ribeiro","sequence":"additional","affiliation":[{"name":"Universidade Estadual de Londrina,  Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7496-7228","authenticated-orcid":false,"given":"Karina Couto","family":"Furlanetto","sequence":"additional","affiliation":[{"name":"Universidade Pit\u00e1goras Unopar Anhanguera,  Brazil; Universidade Estadual de Londrina,  Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"530","published-online":{"date-parts":[[2025]]},"reference":[{"key":"ref1","series-title":"Global strategy for asthma management and prevention","year":"2020"},{"issue":"1","key":"ref2","article-title":"2020 Brazilian Thoracic Association recommendations for the management of asthma","volume":"46","author":"Pizzichini 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