{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T15:07:23Z","timestamp":1753888043189,"version":"3.41.2"},"reference-count":16,"publisher":"FapUNIFESP (SciELO)","issue":"3","license":[{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"am","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rev. Assoc. Med. Bras."],"abstract":"<jats:p>SUMMARY  OBJECTIVE: Myocardial perfusion scintigraphy is a common non-invasive method for assessing ischemic burden, though artifacts can affect accuracy. Speckle-tracking strain echocardiography improves left ventricular function assessment, and global longitudinal strain correlates well with coronary artery disease. The aim of this study was to compare myocardial perfusion scintigraphy with global longitudinal strain in stable angina pectoris patients.  METHODS: A total of 133 suspected coronary artery disease patients who underwent myocardial perfusion scintigraphy and coronary angiography were prospectively enrolled and classified as myocardial perfusion scintigraphy true positives or false positives based on coronary angiography results. Global longitudinal strain values for the epicardium, endocardium, and myocardium (avg) were calculated.  RESULTS: Ischemic percentages of myocardial perfusion scintigraphy&gt;12% and mid-wall global longitudinal strain&lt;-18.4% correlated with true positive coronary angiography results. Left ventricular ejection fraction\/global longitudinal strain mid ratio positively correlated with coronary artery disease presence and severity. Higher ischemic percentages of myocardial perfusion scintigraphy showed a negative correlation (r: \u22120.2606, p: 0.002) with global longitudinal strain, indicating a greater likelihood of coronary artery disease (OR 0.25, 95%CI 0.08\u20130.73, p: 0.012). Female sex was linked to fewer true positive myocardial perfusion scintigraphy results.  CONCLUSION: The GLS value of the Left Ventricle obtained by two-dimentional strain echocardiography offers sensitivity and specificity similar to myocardial perfusion scintigraphy in the detection of coronary artery disease.. An elevated left ventricular ejection fraction\/global longitudinal strain ratio is a significant predictor of the presence and severity of coronary artery disease.<\/jats:p>","DOI":"10.1590\/1806-9282.20241806","type":"journal-article","created":{"date-parts":[[2025,5,2]],"date-time":"2025-05-02T11:07:09Z","timestamp":1746184029000},"source":"Crossref","is-referenced-by-count":0,"title":["Comparison of myocardial perfusion scintigraphy and strain echocardiography in patients undergoing coronary angiography"],"prefix":"10.1590","volume":"71","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2968-5352","authenticated-orcid":false,"given":"\u00c7a\u011flar","family":"Kaya","sequence":"first","affiliation":[{"name":"Trakya University,  Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5650-9066","authenticated-orcid":false,"given":"Muhammet","family":"G\u00fcrdo\u011fan","sequence":"additional","affiliation":[{"name":"Trakya University,  Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"530","published-online":{"date-parts":[[2025]]},"reference":[{"issue":"36","key":"ref1","doi-asserted-by":"crossref","first-page":"3415","DOI":"10.1093\/eurheartj\/ehae177","article-title":"2024 ESC Guidelines for the management of chronic coronary syndromes: developed by the task force for the management of chronic coronary syndromes of the European Society of Cardiology (ESC) Endorsed by the European Association for Cardio-Thoracic Surgery (EACTS)","volume":"45","author":"Vrints C","year":"2024","journal-title":"Eur Heart J"},{"issue":"10","key":"ref2","doi-asserted-by":"crossref","first-page":"1021","DOI":"10.1016\/j.echo.2004.06.019","article-title":"Two-dimensional strain-a novel software for real-time quantitative echocardiographic assessment of myocardial function","volume":"17","author":"Leitman M","year":"2004","journal-title":"J Am Soc Echocardiogr"},{"issue":"2","key":"ref3","doi-asserted-by":"crossref","first-page":"151","DOI":"10.21037\/cdt.2017.03.19","article-title":"Integration of non-invasive functional assessments with anatomical risk stratification in complex coronary artery disease: the non-invasive functional SYNTAX score","volume":"7","author":"Collet C","year":"2017","journal-title":"Cardiovasc Diagn Ther"},{"key":"ref4","first-page":"4","article-title":"2018 ESC\/EACTS guidelines on myocardial revascularization","volume":"55","year":"2018","journal-title":"Eur J Cardio-Thoracic Surg"},{"issue":"12 Pt 1","key":"ref5","doi-asserted-by":"crossref","first-page":"965","DOI":"10.7326\/0003-4819-128-12_Part_1-199806150-00001","article-title":"The electrocardiographic exercise test in a population with reduced workup bias: diagnostic performance, computerized interpretation, and multivariable prediction. Veterans Affairs Cooperative Study in Health Services #016 (QUEXTA) Study Group. Quantitative Exercise Testing and Angiography","volume":"128","author":"Froelicher VF","year":"1998","journal-title":"Ann Intern Med"},{"key":"ref6","series-title":"Nucl Med Semin","first-page":"62","volume-title":"Miyokart perf\u00fczyon sintigrafisi: tuzak ve artefaktlar","volume":"10","author":"Semirgin SU","year":"2024"},{"issue":"1","key":"ref7","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1016\/j.nuclcard.2005.12.004","article-title":"Diagnostic accuracy of rest\/stress ECG-gated Rb-82 myocardial perfusion PET: comparison with ECG-gated Tc-99m sestamibi SPECT","volume":"13","author":"Bateman TM","year":"2006","journal-title":"J Nucl Cardiol"},{"issue":"1","key":"ref8","doi-asserted-by":"crossref","first-page":"62","DOI":"10.4274\/nts.galenos.2024.0006","article-title":"Myocardial perfusion imaging: pitfalls and artifacts","volume":"10","author":"Semirgin SU","year":"2024","journal-title":"Nucl Med Semin"},{"issue":"5","key":"ref9","doi-asserted-by":"crossref","first-page":"836","DOI":"10.1016\/j.ahj.2009.09.010","article-title":"Incremental value of 2-dimensional speckle tracking strain imaging to wall motion analysis for detection of coronary artery disease in patients undergoing dobutamine stress echocardiography","volume":"158","author":"Ng AC","year":"2009","journal-title":"Am Heart J"},{"issue":"5","key":"ref10","doi-asserted-by":"crossref","first-page":"695","DOI":"10.1093\/ejechocard\/jep041","article-title":"Longitudinal 2D strain at rest predicts the presence of left main and three vessel coronary artery disease in patients without regional wall motion abnormality","volume":"10","author":"Choi JO","year":"2009","journal-title":"Eur J Echocardiogr"},{"issue":"1","key":"ref11","article-title":"Clinical study of two-dimensional speckle tracking to evaluate abnormal myocardial motion due to coronary lesions","volume":"41","author":"Sun L","year":"2024","journal-title":"Echocardiography"},{"issue":"3","key":"ref12","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1007\/s00392-015-0916-2","article-title":"Myocardial deformation by strain echocardiography identifies patients with acute coronary syndrome and non-diagnostic ECG presenting in a chest pain unit: a prospective study of diagnostic accuracy","volume":"105","author":"Schroeder J","year":"2016","journal-title":"Clin Res Cardiol"},{"issue":"10","key":"ref13","doi-asserted-by":"crossref","first-page":"2002","DOI":"10.1016\/j.jacc.2006.07.048","article-title":"Myocardial strain and torsion quantified by cardiovascular magnetic resonance tissue tagging: studies in normal and impaired left ventricular function","volume":"48","author":"G\u00f6tte MJ","year":"2006","journal-title":"J Am Coll Cardiol"},{"issue":"1","key":"ref14","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1186\/s43044-021-00173-6","article-title":"Myocardial strain analysis as a non-invasive screening test in the diagnosis of stable coronary artery disease","volume":"73","author":"Akiash N","year":"2021","journal-title":"Egypt Heart J"},{"issue":"2","key":"ref15","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1111\/j.1540-8175.2010.01298.x","article-title":"Left ventricular strain and strain rate echocardiography analysis in patients with total and subtotal occlusion in the infarct-related left anterior descending artery","volume":"28","author":"Kalay N","year":"2011","journal-title":"Echocardiography"},{"issue":"2","key":"ref16","doi-asserted-by":"crossref","DOI":"10.1111\/echo.15769","article-title":"The possible utility of global longitudinal strain in the risk-stratifying process of non-ST elevation-acute coronary syndrome","volume":"41","author":"Fouad A","year":"2024","journal-title":"Echocardiography"}],"container-title":["Revista da Associa\u00e7\u00e3o M\u00e9dica Brasileira"],"original-title":[],"link":[{"URL":"http:\/\/www.scielo.br\/scielo.php?script=sci_pdf&pid=S0104-42302025000300622&tlng=en","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,5,2]],"date-time":"2025-05-02T11:07:12Z","timestamp":1746184032000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.scielo.br\/scielo.php?script=sci_arttext&pid=S0104-42302025000300622&tlng=en"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025]]},"references-count":16,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2025]]}},"alternative-id":["S0104-42302025000300622"],"URL":"https:\/\/doi.org\/10.1590\/1806-9282.20241806","relation":{},"ISSN":["1806-9282","0104-4230"],"issn-type":[{"type":"electronic","value":"1806-9282"},{"type":"print","value":"0104-4230"}],"subject":[],"published":{"date-parts":[[2025]]},"article-number":"e20241806"}}