{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T14:02:23Z","timestamp":1787061743591,"version":"build-2736575974"},"reference-count":19,"publisher":"FapUNIFESP (SciELO)","issue":"3","license":[{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"am","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rev. Assoc. Med. Bras."],"abstract":"<jats:p>SUMMARY  OBJECTIVE: The aim of this study was to compare the efficacy of radial extracorporeal shock wave therapy administered at low vs. high pressures in patients with carpal tunnel syndrome.  METHODS: Patients with carpal tunnel syndrome were randomized into two groups: low-dose group and high-dose group. Each patient underwent a total of four sessions of radial extracorporeal shock wave therapy, administered once a week. The radial extracorporeal shock wave therapy was delivered at 4.0 bars for the high-dose group and 1.5 bars for the low-dose group. Both groups received conventional physical therapy program consisting of transcutaneous electrical nerve stimulation, paraffin wax, orthoses, and tendon gliding exercises, three times per week over a 4-week duration. Outcome measures included pain levels, hand grip strength, pinch strength, the Boston Carpal Tunnel Syndrome Questionnaire, and nerve conduction studies.  RESULTS: Both groups exhibited improvements across all measures, except for the nerve conduction studies parameters. In the intragroup analysis, statistically significant differences were observed with small-to-moderate effect sizes for median motor distal latency, median sensory nerve conduction velocity, median sensory distal latency, and the Boston functional status subscale, all favoring the high-dose group (p&lt;0.05). In the low-dose group, a statistically significant difference with a moderate effect size was noted solely for hand grip strength (p&lt;0.05).  CONCLUSION: High-dose radial extracorporeal shock wave therapy was significantly better than low-dose radial extracorporeal shock wave therapy with small-to-moderate effect sizes in the recovery of the function and nerve conduction studies parameters of patients with carpal tunnel syndrome.  Clinical Trials Registry: The study was registered on the Clinical Trials Registry (registration number: NCT05681663).<\/jats:p>","DOI":"10.1590\/1806-9282.20241815","type":"journal-article","created":{"date-parts":[[2025,5,2]],"date-time":"2025-05-02T07:09:08Z","timestamp":1746169748000},"source":"Crossref","is-referenced-by-count":6,"title":["Comparison of high- and low-dose radial extracorporeal shock wave therapy in carpal tunnel syndrome"],"prefix":"10.1590","volume":"71","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6465-0243","authenticated-orcid":false,"given":"\u0130smail","family":"Ceylan","sequence":"first","affiliation":[{"name":"K\u0131r\u015fehir Ahi Evran University,  Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-2842-946X","authenticated-orcid":false,"given":"B\u00fc\u015fra","family":"K\u00fcrt\u00fcnc\u00fco\u011flu","sequence":"additional","affiliation":[{"name":"K\u0131r\u015fehir Ahi Evran University,  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Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7366-5212","authenticated-orcid":false,"given":"Abdulhamit","family":"Tayfur","sequence":"additional","affiliation":[{"name":"K\u0131r\u015fehir Ahi Evran University,  Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"530","published-online":{"date-parts":[[2025]]},"reference":[{"issue":"4","key":"ref1","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0300044","article-title":"Carpal tunnel syndrome prediction with machine learning algorithms using anthropometric and strength-based measurement","volume":"19","author":"Yeti\u015f M","year":"2024","journal-title":"PLoS One"},{"issue":"4","key":"ref2","doi-asserted-by":"crossref","first-page":"773","DOI":"10.1016\/j.jht.2023.02.004","article-title":"The effectiveness of mobilization with movement on patients with mild and moderate carpal tunnel syndrome: a single-blinded, randomized controlled 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Brasileira"],"original-title":[],"link":[{"URL":"http:\/\/www.scielo.br\/scielo.php?script=sci_pdf&pid=S0104-42302025000300623&tlng=en","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,5,2]],"date-time":"2025-05-02T07:09:14Z","timestamp":1746169754000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.scielo.br\/scielo.php?script=sci_arttext&pid=S0104-42302025000300623&tlng=en"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025]]},"references-count":19,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2025]]}},"alternative-id":["S0104-42302025000300623"],"URL":"https:\/\/doi.org\/10.1590\/1806-9282.20241815","relation":{},"ISSN":["1806-9282","0104-4230"],"issn-type":[{"value":"1806-9282","type":"electronic"},{"value":"0104-4230","type":"print"}],"subject":[],"published":{"date-parts":[[2025]]},"article-number":"e20241815"}}