{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,18]],"date-time":"2026-03-18T22:23:21Z","timestamp":1773872601079,"version":"3.50.1"},"reference-count":14,"publisher":"FapUNIFESP (SciELO)","issue":"7","license":[{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"am","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rev. Assoc. Med. Bras."],"abstract":"<jats:p>SUMMARY  OBJECTIVE: The objective of this study was to assess the risk factors for neonatal death in newborns with gastroschisis.  METHODS: Hospital-based secondary analysis of a retrospective cohort study was performed in a single reference center between January 2014 and December 2023. The following variables were evaluated: maternal characteristics, obstetric aspects, habits, and labor and delivery data. Information on neonatal and hospitalization was also included.  RESULTS: A total of 48 newborns with gastroschisis were delivered, with 27 (56%) being discharged from the hospital, 5 (10%) being transferred to another hospital, and 16 (33%) dying. Maternal origin was associated with neonatal death, with a 4.2 times greater chance of death if the pregnant women came from the interior. Newborns who died started prenatal care significantly earlier than the survivors. Newborns with complex gastroschisis had a 4.05 times higher risk of death, while the lack of primary closure in the first approach increased this risk by a factor of 7.0. Duration of parenteral nutrition, admission to the neonatal intensive care unit, and total hospital stay were significantly shorter in the cases of death, indicating that longer periods were associated with a 5, 6, and 6% reduction in the risk of death, respectively. On the other hand, not wearing the oxygen hood helmet increased the risk of death by 6.94 times. Newborns who spent more days on mechanical ventilation were 9% more likely to die.  CONCLUSION: In conclusion, the only significant variable was the longer time on mechanical ventilation, which was associated with mortality in newborns with gastroschisis.<\/jats:p>","DOI":"10.1590\/1806-9282.20241999","type":"journal-article","created":{"date-parts":[[2025,8,8]],"date-time":"2025-08-08T13:21:57Z","timestamp":1754659317000},"source":"Crossref","is-referenced-by-count":1,"title":["Factors associated with death in newborns with gastroschisis: a retrospective cohort study from a single reference center"],"prefix":"10.1590","volume":"71","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6958-3185","authenticated-orcid":false,"given":"Cinthia Maria Gomes da Costa Escoto","family":"Esteche","sequence":"first","affiliation":[{"name":"Universidade Federal de S\u00e3o Paulo,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6145-2532","authenticated-orcid":false,"given":"Edward","family":"Araujo J\u00fanior","sequence":"additional","affiliation":[{"name":"Universidade Federal de S\u00e3o Paulo,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-3899-321X","authenticated-orcid":false,"given":"Beatriz da Costa Escoto","family":"Esteche","sequence":"additional","affiliation":[{"name":"Centro Universit\u00e1rio Christus,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-9733-9882","authenticated-orcid":false,"given":"Larissa de Oliveira Bernardo","family":"Rodrigues","sequence":"additional","affiliation":[{"name":"Universidade Federal do Cear\u00e1,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0364-6758","authenticated-orcid":false,"given":"Francisco Herl\u00e2nio Costa","family":"Carvalho","sequence":"additional","affiliation":[{"name":"Universidade Federal do Cear\u00e1,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8739-4115","authenticated-orcid":false,"given":"Lilliam Cristine","family":"Rolo","sequence":"additional","affiliation":[{"name":"Universidade Federal de S\u00e3o Paulo,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"530","published-online":{"date-parts":[[2025]]},"reference":[{"issue":"3","key":"ref1","doi-asserted-by":"crossref","first-page":"1587","DOI":"10.3906\/sag-2011-166","article-title":"What is the main factor in predicting the morbidity and mortality in patients with gastroschisis: delivery time, delivery mode, closure method, or the type of gastroschisis (simple or complex)?","volume":"51","author":"Behram M","year":"2021","journal-title":"Turk J Med Sci"},{"issue":"13","key":"ref2","doi-asserted-by":"crossref","first-page":"2225","DOI":"10.3390\/diagnostics13132225","article-title":"Perinatal outcomes of neonates with complex and simple gastroschisis after planned preterm delivery-A single-centre retrospective cohort study","volume":"13","author":"Jaczy\u0144ska R","year":"2023","journal-title":"Diagnostics (Basel)"},{"issue":"6","key":"ref3","doi-asserted-by":"crossref","first-page":"665","DOI":"10.1515\/jpm-2023-0520","article-title":"Factors of poor prognosis in newborns with a prenatal diagnosis of gastroschisis in Bogota, Colombia","volume":"52","author":"D\u00e1vila Romero V","year":"2024","journal-title":"J Perinat Med"},{"issue":"2","key":"ref4","doi-asserted-by":"crossref","DOI":"10.1002\/bdr2.2306","article-title":"Gastroschisis prevalence patterns in 27 surveillance programs from 24 countries, International Clearinghouse for Birth Defects Surveillance and Research, 1980-2017","volume":"116","author":"Feldkamp ML","year":"2024","journal-title":"Birth Defects Res"},{"issue":"10297","key":"ref5","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1016\/S0140-6736(21)00767-4","article-title":"Mortality from gastrointestinal congenital anomalies at 264 hospitals in 74 low-income, middle-income, and high-income countries: a multicentre, international, prospective cohort study","volume":"398","year":"2021","journal-title":"Lancet"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"53","DOI":"10.51866\/cr.278","article-title":"A case report of gastroschisis: prenatal diagnosis in primary care settings matters","volume":"18","author":"Said AH","year":"2023","journal-title":"Malays Fam Physician"},{"issue":"1","key":"ref7","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1016\/j.jped.2021.04.007","article-title":"Gastroschisis annual incidence, mortality, and trends in extreme Southern Brazil","volume":"98","author":"Egger PA","year":"2022","journal-title":"J Pediatr (Rio J)"},{"issue":"8","key":"ref8","doi-asserted-by":"crossref","first-page":"1269","DOI":"10.1080\/14767058.2019.1633303","article-title":"Fetal abdominal wall defects in an Australian tertiary setting: contemporary characteristics, ultrasound accuracy, and outcome","volume":"34","author":"Filippo D","year":"2021","journal-title":"J Matern Fetal Neonatal Med"},{"issue":"22","key":"ref9","doi-asserted-by":"crossref","first-page":"5215","DOI":"10.3390\/jcm10225215","article-title":"Ultrasound markers for complex gastroschisis: a systematic review and meta-analysis","volume":"10","author":"Ferreira RG","year":"2021","journal-title":"J Clin Med"},{"issue":"10","key":"ref10","first-page":"1504","article-title":"Improved mortality of patients with gastroschisis: a historical literature review of advances in surgery and critical care from 1960-2020","volume":"9","author":"Georgeades C","year":"2022","journal-title":"Children (Basel)"},{"issue":"8","key":"ref11","doi-asserted-by":"crossref","first-page":"540","DOI":"10.3390\/diagnostics10080540","article-title":"Prenatal prediction of outcome by fetal gastroschisis in a tertiary referral center","volume":"10","author":"Nitzsche 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(Larchmt)"}],"container-title":["Revista da Associa\u00e7\u00e3o M\u00e9dica 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