{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T15:17:56Z","timestamp":1761578276874,"version":"build-2065373602"},"reference-count":15,"publisher":"FapUNIFESP (SciELO)","issue":"10","license":[{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"am","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rev. Assoc. Med. Bras."],"abstract":"<jats:p>SUMMARY  OBJECTIVE: The aim of the study was to evaluate the incidence of early-onset neonatal sepsis and other perinatal adverse outcomes associated with not screening for group B beta-hemolytic Streptococcus.  METHODS: A retrospective cohort study was conducted by searching electronic medical records from 2018 to 2022. Group B beta-hemolytic Streptococcus culture was performed after routine collection of vaginal and anal swabs from pregnant women at any time of pregnancy..  RESULTS: A total of 968 pregnant women were included; 69.3% (675\/968) were screened for group B beta-hemolytic Streptococcus, and 30.3% were not screened for group B beta-hemolytic Streptococcus. Of the pregnant women who were screened, 30.5% (206\/675) had positive cultures and 69.5% (469\/675) had negative cultures for group B beta-hemolytic Streptococcus. Pregnant women who underwent group B beta-hemolytic Streptococcus screening had a lower prevalence of preterm birth (p&lt;0.0001), neonatal intensive care unit (NICU) admission (p=0.001), and neonatal death within 48 h (p=0.002). Group B beta-hemolytic Streptococcus screening was an independent predictor of preterm birth (p&lt;0.0001). The best model for neonatal death in the first 48 h included group B beta-hemolytic Streptococcus screening (p=0.035) and NICU admission (p=0.016). Antibiotic use (p=0.040), preterm birth (p&lt;0.0001), premature rupture of ovular membranes (p=0.047), premature delivery (p&lt;0.0001), and chorioamnionitis (p=0.001) were associated with an increased risk of early-onset neonatal sepsis.  CONCLUSIONS: Screening for group B beta-hemolytic Streptococcus was not significantly associated with early-onset neonatal sepsis, but it was an independent predictor of preterm birth.<\/jats:p>","DOI":"10.1590\/1806-9282.20250077","type":"journal-article","created":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T15:04:13Z","timestamp":1761577453000},"source":"Crossref","is-referenced-by-count":0,"title":["Association between group B beta-hemolytic Streptococcus screening during pregnancy and the prevalence of early-onset neonatal sepsis"],"prefix":"10.1590","volume":"71","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4599-1007","authenticated-orcid":false,"given":"Thamirys Pereira","family":"Rodrigues","sequence":"first","affiliation":[{"name":"Universidade de Uberaba,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-4525-525X","authenticated-orcid":false,"given":"Marianna Camilo","family":"Rezende","sequence":"additional","affiliation":[{"name":"Universidade de Uberaba,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-8224-2963","authenticated-orcid":false,"given":"Isadora Acerbi","family":"Manfrin","sequence":"additional","affiliation":[{"name":"Universidade de Uberaba,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6145-2532","authenticated-orcid":false,"given":"Edward","family":"Araujo J\u00fanior","sequence":"additional","affiliation":[{"name":"Universidade Federal de S\u00e3o Paulo,  Brazil; Universidade Municipal de S\u00e3o Caetano do Sul,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1655-3609","authenticated-orcid":false,"given":"Alberto Borges","family":"Peixoto","sequence":"additional","affiliation":[{"name":"Universidade de Uberaba,  Brazil; Universidade Federal do Tri\u00e2ngulo Mineiro,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"530","published-online":{"date-parts":[[2025]]},"reference":[{"issue":"10104","key":"ref1","doi-asserted-by":"crossref","first-page":"1770","DOI":"10.1016\/S0140-6736(17)31002-4","article-title":"Neonatal sepsis","volume":"390","author":"Shane AL","year":"2017","journal-title":"Lancet"},{"issue":"2","key":"ref2","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1016\/S0002-9378(16)32589-3","article-title":"Premature rupture of membranes, preterm delivery, and group B streptococcal colonization of mothers","volume":"141","author":"Regan JA","year":"1981","journal-title":"Am J Obstet Gynecol"},{"issue":"3","key":"ref3","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1084\/jem.61.3.335","article-title":"The serological differentiation of pathogenic and non-pathogenic strains of hemolytic streptococci from parturient women","volume":"61","author":"Lancefield RC","year":"1935","journal-title":"J Exp Med"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"1221","DOI":"10.1056\/NEJM196412102712401","article-title":"Neonatal sepsis and other infections due to group B beta-hemolytic streptococci","volume":"271","author":"Eickhoff TC","year":"1964","journal-title":"N Engl J Med"},{"issue":"3","key":"ref5","doi-asserted-by":"crossref","first-page":"689","DOI":"10.1016\/j.pcl.2009.04.003","article-title":"Group B Streptococcus and early-onset sepsis in the era of maternal prophylaxis","volume":"56","author":"Koenig JM","year":"2009","journal-title":"Pediatr Clin North Am"},{"year":"2023","series-title":"Servi\u00e7os de Informa\u00e7\u00e3o EBSCO. 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