{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,3]],"date-time":"2026-08-03T11:45:52Z","timestamp":1785757552499,"version":"3.56.0"},"reference-count":22,"publisher":"FapUNIFESP (SciELO)","issue":"7","license":[{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"am","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rev. Assoc. Med. Bras."],"abstract":"<jats:p>SUMMARY  OBJECTIVE: The aim of this study was to describe sexual life and determine the prevalence of erectile dysfunction in men with chronic obstructive pulmonary disease.  METHODS: A multicenter cross-sectional study was conducted with 120 male patients diagnosed with chronic obstructive pulmonary disease for 2 years since 2021. Participants completed a comprehensive questionnaire that included the International Index of Erectile Function, selected items from the Questionnaire on Changes in Sexual Function, and additional questions about sexual health. Erectile dysfunction was considered clinically significant with an International Index of Erectile Function score \u226416. No formal a priori sample size calculation was performed because participant recruitment was based on consecutive inclusion during a 2-year study period.  RESULTS: In total, 113 participants (94.2%) reported experiencing changes in their sex life and 42 (36%) were dissatisfied. The main factors contributing to these changes were the underlying disease (53.3%), medication use (20.8%), and psychological problems (20%). The mean International Index of Erectile Function score was 13.8 (7.0), with an erectile dysfunction prevalence of 87.5%. Erectile dysfunction was mild in 33 patients (27.5%), mild-to-moderate in 26 (21.7%), moderate in 21 (17.5%), and severe in 25 (20.8%). Multivariate analysis identified dyslipidemia (odds ratio: 4.028; 95%CI 1.428\u201311.361; p=0.008) and %pFEV1 (OR 0.937; 95%CI 0.906\u20130.968; p&lt;0.001) as independent predictors of clinically significant erectile dysfunction.  CONCLUSION: Poor sexual health and erectile dysfunction are highly prevalent among men with chronic obstructive pulmonary disease. Dyslipidemia and impaired airflow are associated with the presence of clinically significant erectile dysfunction.<\/jats:p>","DOI":"10.1590\/1806-9282.20252266","type":"journal-article","created":{"date-parts":[[2026,8,3]],"date-time":"2026-08-03T11:00:48Z","timestamp":1785754848000},"source":"Crossref","is-referenced-by-count":0,"title":["Erectile dysfunction in men with chronic obstructive pulmonary disease: cross-sectional study in a Spanish population"],"prefix":"10.1590","volume":"72","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9462-3190","authenticated-orcid":false,"given":"Nicol\u00e1s","family":"Alcal\u00e1-Rivera","sequence":"first","affiliation":[{"name":"Barbastro Hospital,  Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3132-2171","authenticated-orcid":false,"given":"Jes\u00fas","family":"D\u00edez-Manglano","sequence":"additional","affiliation":[{"name":"Hospital Royo Villanova,  Spain; Barbastro Hospital,  Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"530","published-online":{"date-parts":[[2026]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1016\/S2213-2600(21)00511-7","article-title":"Global, regional, and national prevalence of, and risk factors for, chronic obstructive pulmonary disease (COPD) in 2019: a systematic review and modelling analysis.","volume":"10","author":"Adeloye D","year":"2022","journal-title":"Lancet Respir Med"},{"key":"ref2","year":"2024"},{"issue":"9","key":"ref3","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1016\/S2213-2600(17)30293-X","article-title":"Global, regional, and national deaths, prevalence, disability-adjusted life years, and years lived with disability for chronic obstructive pulmonary disease and asthma, 1990\u20132015: a systematic analysis for the Global Burden of Disease Study 2015.","volume":"5","author":"Soriano JB","year":"2017","journal-title":"Lancet Respir 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dysfunction in women with chronic obstructive lung disease.","volume":"224","author":"Alcala-Rivera N","year":"2024","journal-title":"Rev Clin Esp"},{"key":"ref8","year":"2024"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1038\/sj.ijir.3900472","article-title":"Development and evaluation of an abridged, 5-item version of the International Index of Erectile Function (IIEF-5) as a diagnostic tool for erectile dysfunction.","volume":"11","author":"Rosen RC","year":"1999","journal-title":"Int J Impot Res"},{"key":"ref10","first-page":"731","article-title":"The Changes in Sexual Functioning Questionnaire (CSFQ): development, reliability, and validity.","volume":"33","author":"Clayton AH","year":"1997","journal-title":"Psychopharmacol Bull"},{"issue":"11","key":"ref11","doi-asserted-by":"crossref","first-page":"1245","DOI":"10.1016\/0895-4356(94)90129-5","article-title":"Validation of a combined comorbidity index.","volume":"47","author":"Charlson 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Chronic Obstructive Pulmonary Disease and Erectile Dysfunction? The DECODED study.","volume":"23","author":"Dias M","year":"2017","journal-title":"Rev Port Pneumol (2006)"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"16003","DOI":"10.1038\/nrdp.2016.3","article-title":"Erectile dysfunction.","volume":"2","author":"Yafi FA","year":"2016","journal-title":"Nat Rev Dis Primers"},{"issue":"4","key":"ref17","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1111\/j.2047-2927.2013.00102.x","article-title":"Endothelial function in patients with metabolic syndrome and erectile dysfunction: a question of angiopoietin imbalance?","volume":"1","author":"Tomada N","year":"2013","journal-title":"Andrology"},{"issue":"5","key":"ref18","doi-asserted-by":"crossref","first-page":"496","DOI":"10.1038\/sj.ijir.3901560","article-title":"The role of hypoxia in erectile dysfunction mechanisms.","volume":"19","author":"Verratti V","year":"2007","journal-title":"Int J Impot Res"},{"key":"ref19","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1177\/1479972315619382","article-title":"Erectile dysfunction in COPD patients.","volume":"13","author":"Turan O","year":"2016","journal-title":"Chron Respir Dis"},{"issue":"10","key":"ref20","doi-asserted-by":"crossref","first-page":"2376","DOI":"10.1111\/jsm.12641","article-title":"Association of quantity and duration of smoking with erectile dysfunction: a dose-response meta-analysis.","volume":"11","author":"Cao S","year":"2014","journal-title":"J Sex Med"},{"key":"ref21","doi-asserted-by":"crossref","first-page":"165","DOI":"10.4081\/aiua.2016.3.165","article-title":"Chronic obstructive pulmonary disease (COPD) and erectile dysfunction (ED): results of the BRED observational study.","volume":"88","author":"Lauretti S","year":"2016","journal-title":"Arch Ital Urol Androl"},{"issue":"7","key":"ref22","doi-asserted-by":"crossref","first-page":"1626","DOI":"10.1111\/jsm.12521","article-title":"The effect of statins on erectile dysfunction: a meta-analysis of randomized trials.","volume":"11","author":"Kostis JB","year":"2014","journal-title":"J Sex Med"}],"container-title":["Revista da Associa\u00e7\u00e3o M\u00e9dica Brasileira"],"original-title":[],"link":[{"URL":"http:\/\/www.scielo.br\/scielo.php?script=sci_pdf&pid=S0104-42302026000702209&tlng=en","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,3]],"date-time":"2026-08-03T11:00:53Z","timestamp":1785754853000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.scielo.br\/scielo.php?script=sci_arttext&pid=S0104-42302026000702209&tlng=en"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026]]},"references-count":22,"journal-issue":{"issue":"7","published-online":{"date-parts":[[2026]]}},"alternative-id":["S0104-42302026000702209"],"URL":"https:\/\/doi.org\/10.1590\/1806-9282.20252266","relation":{},"ISSN":["1806-9282","0104-4230"],"issn-type":[{"value":"1806-9282","type":"electronic"},{"value":"0104-4230","type":"print"}],"subject":[],"published":{"date-parts":[[2026]]},"article-number":"e20252266"}}