{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,26]],"date-time":"2025-10-26T21:18:32Z","timestamp":1761513512537,"version":"3.40.4"},"reference-count":46,"publisher":"FapUNIFESP (SciELO)","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rev. Assoc. Med. Bras."],"published-print":{"date-parts":[[2014,7]]},"abstract":"<jats:p>Objective: to determine the prevalence of abnormal total cholesterol (TC), low density lipoprotein (LDL), high density lipoprotein (HDL) and triglycerides in patients undergoing liver transplantation (LTx) and to identify predictors of these disorders. Methods: cross-sectional study to assess the prevalence of dyslipidemia in patients undergoing LTx. Demographic, socioeconomic, clinical, anthropometric and dietetic data were collected to determine the association with dyslipidemia using univariate and multivariate statistical analysis. Results: 136 patients were evaluated, 68.1% of which had at least one type of dyslipidemia. The triglyceride level was high in 32.4% of cases, with low HDL in 49.3% of patients and high LDL levels in only 8.8%. High total cholesterol was observed in 16.2% of the study population and was associated with the recommendation for transplantation due to ethanolic cirrhosis (OR = 2.7) and a greater number of hours slept per night (OR = 1.5). Conclusion: many patients presented dyslipidemia after transplantation, demonstrating the need for interventions in relation to modifiable factors associated with dyslipidemias that can mitigate or prevent these disorders.<\/jats:p>","DOI":"10.1590\/1806-9282.60.04.016","type":"journal-article","created":{"date-parts":[[2014,9,3]],"date-time":"2014-09-03T17:55:16Z","timestamp":1409766916000},"page":"365-372","source":"Crossref","is-referenced-by-count":9,"title":["Prevalence and factors associated with dyslipidemia after liver transplantation"],"prefix":"10.1590","volume":"60","author":[{"given":"H\u00e9lem de Sena","family":"Ribeiro","sequence":"first","affiliation":[{"name":"Federal University of Minas Gerais, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lucilene Rezende","family":"Anast\u00e1cio","sequence":"additional","affiliation":[{"name":"Federal University of Minas Gerais, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L\u00edvia Garcia","family":"Ferreira","sequence":"additional","affiliation":[{"name":"Federal University of Minas Gerais, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"\u00c9rika Barbosa","family":"Lagares","sequence":"additional","affiliation":[{"name":"University of Ita\u00fana, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Agnaldo Soares","family":"Lima","sequence":"additional","affiliation":[{"name":"Federal University of Minas Gerais, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria Isabel Toulson Davisson","family":"Correia","sequence":"additional","affiliation":[{"name":"Federal University of Minas Gerais, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"530","reference":[{"key":"ref1","first-page":"1","article-title":"IV Diretriz Brasileira Sobre Dislipidemias e Preven\u00e7\u00e3o da Aterosclerose Departamento de Aterosclerose da Sociedade Brasileira de Cardiologia","volume":"8","author":"Sposito AC","year":"2007","journal-title":"Arq Bras Cardiol"},{"issue":"4","key":"ref2","doi-asserted-by":"crossref","first-page":"416","DOI":"10.1002\/lt.500030409","article-title":"Hyperlipidemia in liver transplant recipients: prevalence and risk factors","volume":"3","author":"Gisbert C","year":"1997","journal-title":"Liver Transpl Surg"},{"issue":"11","key":"ref3","doi-asserted-by":"crossref","first-page":"1648","DOI":"10.1002\/lt.21588","article-title":"Metabolic syndrome in liver transplantation: relation to etiology and immunosuppression","volume":"14","author":"Bianchi G","year":"2008","journal-title":"Liver Transpl"},{"issue":"1","key":"ref4","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1111\/j.1399-0012.1997.tb00782.x","article-title":"Cardiovascular risk factors in long-term follow-up after orthotopic liver transplantation","volume":"11","author":"Guckelberger O","year":"1997","journal-title":"Clin Transplant"},{"issue":"8","key":"ref5","doi-asserted-by":"crossref","first-page":"1109","DOI":"10.1002\/lt.21126","article-title":"Metabolic syndrome in liver transplant recipients: prevalence and association with major vascular events","volume":"13","author":"Laryea M","year":"2007","journal-title":"Liver Transpl"},{"issue":"6","key":"ref6","doi-asserted-by":"crossref","first-page":"2381","DOI":"10.1016\/j.transproceed.2010.05.007","article-title":"Long-term complications and survival of patients after orthotopic liver transplantation","volume":"42","author":"Mu\u00f1oz LE","year":"2010","journal-title":"Transplant Proc"},{"issue":"9","key":"ref7","doi-asserted-by":"crossref","first-page":"1287","DOI":"10.1002\/lt.21524","article-title":"The significance of metabolic syndrome in the setting of recurrent hepatitis C after liver transplantation","volume":"14","author":"Hanouneh IA","year":"2008","journal-title":"Liver Transpl"},{"issue":"3","key":"ref8","doi-asserted-by":"crossref","first-page":"394","DOI":"10.1002\/lt.20722","article-title":"Validation of cardiovascular risk scores in a liver transplant population","volume":"12","author":"Guckelberger O","year":"2006","journal-title":"Liver Transpl"},{"issue":"2","key":"ref9","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1053\/jlts.2001.21289","article-title":"Tacrolimus conversion improves hyperlipidemic states in stable liver transplant recipients","volume":"7","author":"Manzarbeitia C","year":"2001","journal-title":"Liver Transpl"},{"issue":"2","key":"ref10","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1111\/j.1432-2277.1998.tb00789.x","article-title":"Lipid abnormalities in stable liver transplant recipients-effects of cyclosporin, tacrolimus, and steroids","volume":"11","author":"Fernandez-Miranda C","year":"1998","journal-title":"Transpl Int"},{"issue":"7","key":"ref11","doi-asserted-by":"crossref","first-page":"1036","DOI":"10.1097\/00007890-199904150-00017","article-title":"Sirolimus (rapamycin)-based therapy in human renal transplantation: similar efficacy and different toxicity compared with cyclosporine","volume":"67","author":"Groth CG","year":"1999","journal-title":"Transplantation"},{"issue":"3","key":"ref12","doi-asserted-by":"crossref","first-page":"319","DOI":"10.2105\/AJPH.81.3.319","article-title":"Race and weight change in US women: the roles of socioeconomic and marital status","volume":"81","author":"Kahn HS","year":"1991","journal-title":"Am J Public Health"},{"issue":"6","key":"ref13","doi-asserted-by":"crossref","first-page":"642","DOI":"10.1111\/j.1399-0012.2004.00253.x","article-title":"Dyslipidemia during sirolimus therapy in patients after liver transplantation","volume":"18","author":"Kniepeiss D","year":"2004","journal-title":"Clin Transplant"},{"issue":"5","key":"ref14","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1053\/jlts.2001.23916","article-title":"Dyslipidemia during sirolimus therapy in liver transplant recipients occurs with concomitant cyclosporine but not tacrolimus","volume":"7","author":"Trotter JF","year":"2001","journal-title":"Liver Transpl"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1590\/S0066-782X2001001500001","article-title":"III Brazilian Guidelines on Dyslipidemias and Guideline of Atherosclerosis Prevention from Atherosclerosis Department of Sociedade Brasileira de Cardiologia","volume":"77","author":"Santos RD","year":"2001","journal-title":"Arq Bras Cardiol"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"498","DOI":"10.1097\/00005768-200009001-00009","article-title":"Compendium of physical activities: an update of activity codes and MET intensities","volume":"32","author":"Ainsworth BE","year":"2000","journal-title":"Med Sci Sports Exerc"},{"year":"1985","series-title":"Energy and protein requirements","key":"ref17"},{"year":"1998","series-title":"Obesity: preventing and managing the global epidemic","key":"ref18"},{"issue":"5","key":"ref19","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1111\/j.1464-5491.2006.01858.x","article-title":"Metabolic syndrome--a new world-wide definition. A Consensus Statement from the International Diabetes Federation","volume":"23","author":"Alberti KG","year":"2006","journal-title":"Diabet Med"},{"year":"2001","series-title":"Tabela de composi\u00e7\u00e3o de alimentos: suporte para decis\u00e3o nutricional","author":"Phillipi ST","key":"ref20"},{"year":"2000","series-title":"Tabela para avalia\u00e7\u00e3o de consumo alimentar em medidas caseiras","author":"Pinheiro ABVL","key":"ref21"},{"issue":"9","key":"ref22","doi-asserted-by":"crossref","first-page":"769","DOI":"10.1007\/s00535-007-2092-2","article-title":"Hyperlipidemia in Iranian liver transplant recipients: prevalence and risk factors","volume":"42","author":"Dehghani SM","year":"2007","journal-title":"J Gastroenterol"},{"key":"ref23","first-page":"1480","article-title":"Hyperlipidemia and obesity after orthotopic liver transplantation","volume":"23","author":"Munoz SJ","year":"1991","journal-title":"Transplant Proc"},{"issue":"4","key":"ref24","doi-asserted-by":"crossref","first-page":"591","DOI":"10.1016\/j.cld.2009.07.011","article-title":"Predictors of steatohepatitis and advanced fibrosis in non-alcoholic fatty liver disease","volume":"13","author":"Pagadala M","year":"2009","journal-title":"Clin Liver Dis"},{"issue":"3","key":"ref25","first-page":"249","article-title":"Prevalence of dyslipidemia and risk factors in Campos dos Goytacazes, in the Brazilian state of Rio de Janeiro","volume":"81","author":"de Souza LJ","year":"2003","journal-title":"Arq Bras Cardiol"},{"issue":"6","key":"ref26","first-page":"395","article-title":"Prevalence of dyslipidemias in adults in laboratory tests from Salvador, Brazil","volume":"69","author":"Lessa I","year":"1997","journal-title":"Arq Bras Cardiol"},{"issue":"1","key":"ref27","first-page":"24","article-title":"Epidemiologia das dislipidemias","volume":"16","author":"Bertolami MC","year":"2006","journal-title":"Rev Soc Cardiol Estado de S\u00e3o Paulo"},{"issue":"10","key":"ref28","doi-asserted-by":"crossref","first-page":"699","DOI":"10.1093\/qjmed\/hcg120","article-title":"Non-alcoholic fatty liver: a common manifestation of a metabolic disorder","volume":"96","author":"Malnick SD","year":"2003","journal-title":"QJM"},{"issue":"9","key":"ref29","doi-asserted-by":"crossref","first-page":"797","DOI":"10.1053\/jlts.2001.24644","article-title":"Cryptogenic cirrhosis and posttransplantation nonalcoholic fatty liver disease","volume":"7","author":"Ong J","year":"2001","journal-title":"Liver Transpl"},{"issue":"3","key":"ref30","doi-asserted-by":"crossref","first-page":"910","DOI":"10.1093\/ajcn\/85.3.910","article-title":"Dietary patterns, insulin resistance, and prevalence of the metabolic syndrome in women","volume":"85","author":"Esmaillzadeh A","year":"2007","journal-title":"Am J Clin Nutr"},{"issue":"20","key":"ref31","doi-asserted-by":"crossref","first-page":"2569","DOI":"10.1001\/jama.288.20.2569","article-title":"Optimal diets for prevention of coronary heart disease","volume":"288","author":"Hu FB","year":"2002","journal-title":"JAMA"},{"issue":"3","key":"ref32","doi-asserted-by":"crossref","first-page":"785","DOI":"10.1038\/oby.2007.593","article-title":"Measures of adiposity and cardiovascular disease risk factors","volume":"15","author":"Menke A","year":"2007","journal-title":"Obesity"},{"issue":"6","key":"ref33","doi-asserted-by":"crossref","first-page":"883","DOI":"10.2337\/diabetes.49.6.883","article-title":"The perils of portliness: causes and consequences of visceral adiposity","volume":"49","author":"Montague CT","year":"2000","journal-title":"Diabetes"},{"issue":"2","key":"ref34","doi-asserted-by":"crossref","first-page":"95","DOI":"10.2174\/157339907780598207","article-title":"Management of obesity in patients with type 2 diabetes mellitus","volume":"3","author":"Gagliardi L","year":"2007","journal-title":"Curr Diabetes Rev"},{"issue":"5","key":"ref35","doi-asserted-by":"crossref","first-page":"320","DOI":"10.1016\/j.dld.2010.01.016","article-title":"From the metabolic syndrome to NAFLD or vice versa?","volume":"42","author":"Vanni E","year":"2010","journal-title":"Dig Liver Dis"},{"issue":"9468","key":"ref36","doi-asserted-by":"crossref","first-page":"1415","DOI":"10.1016\/S0140-6736(05)66378-7","article-title":"The metabolic syndrome","volume":"365","author":"Eckel RH","year":"2005","journal-title":"Lancet"},{"issue":"2","key":"ref37","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1093\/ajcn\/79.2.213","article-title":"Fruit and vegetable consumption and LDL cholesterol: the National Heart, Lung, and Blood Institute Family Heart Study","volume":"79","author":"Djousse L","year":"2004","journal-title":"Am J Clin Nutr"},{"issue":"9","key":"ref38","doi-asserted-by":"crossref","first-page":"1330","DOI":"10.1002\/lt.21247","article-title":"Employment and quality of life in liver transplant recipients","volume":"13","author":"Saab S","year":"2007","journal-title":"Liver Transpl"},{"issue":"3","key":"ref39","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1053\/jlts.2001.22184","article-title":"Physical activity and health-related quality of life in liver transplant recipients","volume":"7","author":"Painter P","year":"2001","journal-title":"Liver Transpl"},{"issue":"4","key":"ref40","first-page":"549","article-title":"Coronary heart disease, physical exercise and oxidative stress","volume":"94","author":"Pinho RA","journal-title":"Arq Bras Cardiol"},{"issue":"1","key":"ref41","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1053\/j.jrn.2008.10.002","article-title":"Metabolic syndrome after kidney transplantation","volume":"19","author":"Bellinghieri G","year":"2009","journal-title":"J Ren Nutr"},{"issue":"3","key":"ref42","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1038\/ncpendmet1066","article-title":"Dyslipidemia in type 2 diabetes mellitus","volume":"5","author":"Mooradian AD","year":"2009","journal-title":"Nat Clin Pract Endocrinol Metab"},{"issue":"7","key":"ref43","doi-asserted-by":"crossref","first-page":"956","DOI":"10.1093\/sleep\/33.7.956","article-title":"Short sleep duration as a risk factor for hypercholesterolemia: analyses of the National Longitudinal Study of Adolescent Health","volume":"33","author":"Gangwisch JE","year":"2010","journal-title":"Sleep"},{"issue":"2","key":"ref44","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1111\/j.0889-7204.2004.02422.x","article-title":"The impact of daily sleep duration on health: a review of the literature","volume":"19","author":"Alvarez GG","year":"2004","journal-title":"Prog Cardiovasc Nurs"},{"issue":"4","key":"ref45","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1093\/sleep\/31.4.517","article-title":"The association between sleep duration and weight gain in adults: a 6-year prospective study from the Quebec Family Study","volume":"31","author":"Chaput JP","year":"2008","journal-title":"Sleep"},{"issue":"2","key":"ref46","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1093\/ajcn\/42.2.289","article-title":"Alcohol consumption, nutrient intake and relative body weight among US adults","volume":"42","author":"Gruchow HW","year":"1985","journal-title":"Am J Clin Nutr"}],"container-title":["Revista da Associa\u00e7\u00e3o M\u00e9dica Brasileira"],"original-title":[],"link":[{"URL":"http:\/\/www.scielo.br\/pdf\/ramb\/v60n4\/0104-4230-ramb-60-04-0365.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,5,4]],"date-time":"2025-05-04T13:09:33Z","timestamp":1746364173000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.scielo.br\/scielo.php?script=sci_arttext&pid=S0104-42302014000400365&lng=en&tlng=en"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,7]]},"references-count":46,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2014,7]]}},"alternative-id":["S0104-42302014000400365"],"URL":"https:\/\/doi.org\/10.1590\/1806-9282.60.04.016","relation":{},"ISSN":["0104-4230"],"issn-type":[{"type":"electronic","value":"0104-4230"}],"subject":[],"published":{"date-parts":[[2014,7]]}}}