{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T14:09:36Z","timestamp":1791295776460,"version":"4.1.0"},"reference-count":24,"publisher":"FapUNIFESP (SciELO)","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rev. Assoc. Med. Bras."],"published-print":{"date-parts":[[2014,12]]},"abstract":"<jats:p>                Objective:                despite endometriosis being a common disease, where early detection is key to                   preventing its progression, it is a condition often overlooked in adolescents. The                   aim of this study was to report the clinical characteristics of adolescent                   patients with endometriosis monitored in a tertiary hospital.                                          Methods:                a retrospective study of 394 patients undergoing surgery with a histological                   diagnosis of endometriosis at the Endometriosis Division of the Gynecology                   Department at the Hospital das Cl\u00ednicas of the University of S\u00e3o Paulo Medical                   School from 2008 to 2013. 21 adolescents were included (aged under 21 years).                                          Results:                the age ranged from 17.95 \u00b1 1.48 years, the average time for diagnostic                   confirmation was 2.96 \u00b1 2.93 years, and the age at the onset of symptoms was 15.28                   \u00b1 3.03 years on average. The sites affected were ovarian (38%), peritoneal (47.6%)                   and retrocervical (23.8%). Dysmenorrhea was found in 80.9 % of adolescents (severe                   in 33.3% of cases) and chronic pelvic pain in 66.6%.                                          Conclusion:                endometriosis in adolescents is an important differential diagnosis from pelvic                   pain and ovarian cysts, mainly among those with no response to conventional                   treatment. The main forms of involvement are peritoneal and ovarian. Despite the                   onset of symptoms in adolescence and advances in imaging methods, the diagnosis of                   this disease is still delayed.<\/jats:p>","DOI":"10.1590\/1806-9282.60.06.015","type":"journal-article","created":{"date-parts":[[2015,1,28]],"date-time":"2015-01-28T19:32:28Z","timestamp":1422473548000},"page":"560-564","source":"Crossref","is-referenced-by-count":19,"title":["Endometriosis is an important cause of pelvic pain in                adolescence"],"prefix":"10.1590","volume":"60","author":[{"given":"Marina de Paula","family":"Andres","sequence":"first","affiliation":[{"name":"University of S\u00e3o Paulo,  Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sergio","family":"Podgaec","sequence":"additional","affiliation":[{"name":"University of S\u00e3o Paulo,  Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karina Belickas","family":"Carreiro","sequence":"additional","affiliation":[{"name":"HC-FMUSP,  Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edmund Chada","family":"Baracat","sequence":"additional","affiliation":[{"name":"FMUSP,  Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"530","reference":[{"issue":"6","key":"ref1","doi-asserted-by":"crossref","first-page":"778","DOI":"10.1016\/j.biocel.2010.03.008","article-title":"Endometriosis: new concepts in the                   pathogenesis","volume":"42","author":"Signorile PG","year":"2010","journal-title":"Int J Biochem Cell Biol"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1196\/annals.1429.007","article-title":"Dysmenorrhea in adolescents","volume":"1135","author":"Harel Z","year":"2008","journal-title":"Ann N Y Acad Sci"},{"issue":"5","key":"ref3","doi-asserted-by":"crossref","first-page":"s260","DOI":"10.1016\/j.fertnstert.2008.08.057","article-title":"Treatment of pelvic pain associated with                   endometriosis","volume":"90","year":"2008","journal-title":"Fertil Steril"},{"issue":"4","key":"ref4","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1111\/j.1600-0897.2012.01173.x","article-title":"CD4( ) CD25(high) Foxp3( ) cells increased in the                   peritoneal fluid of patients with endometriosis","volume":"68","author":"Podgaec S","year":"2012","journal-title":"Am J Reprod Immunol"},{"issue":"3","key":"ref5","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1056\/NEJMra0804690","article-title":"Endometriosis","volume":"360","author":"Bulun SE","year":"2009","journal-title":"N Engl J Med"},{"issue":"25","key":"ref6","first-page":"446","article-title":"The diagnosis and treatment of deep infiltrating                   endometriosis","volume":"107","author":"Hails G","year":"2010","journal-title":"Dtsch Arztebl Int"},{"issue":"4","key":"ref7","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1016\/S0015-0282(97)00191-X","article-title":"Peritoneal endometriosis, ovarian endometriosis, and                   adenomyotic nodules of the rectovaginal septum are three different                   entities","volume":"68","author":"Nisolle M","year":"1997","journal-title":"Fertil Steril"},{"issue":"7247","key":"ref8","doi-asserted-by":"crossref","first-page":"1449","DOI":"10.1136\/bmj.320.7247.1449","article-title":"Extracts from the \"clinical evidence\".                   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