{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T20:41:49Z","timestamp":1788295309033,"version":"build-2803163510"},"reference-count":23,"publisher":"FapUNIFESP (SciELO)","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rev. Assoc. Med. Bras."],"published-print":{"date-parts":[[2015,4]]},"abstract":"<jats:p>Summary Acute pericarditis is a common disease caused by inflammation of the pericardium, usually benign and self-limited and can occur as an isolated or as a manifestation of a systemic disease entity. Represents 5% of all causes of chest pain in the emergency room. The main etiology are viral infections, although it can also be secondary to systemic diseases and infections. The main complication of acute pericarditis is pericardial effusion, triggering a cardiac tamponade. The first line of treatment is the use of anti-inflammatory and or acetylsalicylic acid. Most patients have a good initial response to an NSAID associated to colchicine and became asymptomatic within a few days. This review article seeks to contemplate the main clinical findings and armed investigation to optimize the diagnosis of this important disease, as well as addressing their therapeutic management.<\/jats:p>","DOI":"10.1590\/1806-9282.61.02.184","type":"journal-article","created":{"date-parts":[[2015,6,17]],"date-time":"2015-06-17T18:53:52Z","timestamp":1434567232000},"page":"184-190","source":"Crossref","is-referenced-by-count":16,"title":["Acute pericarditis"],"prefix":"10.1590","volume":"61","author":[{"given":"M\u00e1rcio","family":"Tonini","sequence":"first","affiliation":[{"name":"University of S\u00e3o Paulo,  Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dirceu Thiago Pessoa de","family":"Melo","sequence":"additional","affiliation":[{"name":"USP,  Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F\u00e1bio","family":"Fernandes","sequence":"additional","affiliation":[{"name":"USP,  Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"530","reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1016\/j.ehj.2004.02.002","article-title":"Guidelines on the diagnosis and management of pericardial diseases executive summary: the Task Force on the Diagnosis and Management of Pericardial Diseases of the European Society of Cardiology","volume":"25","author":"Maisch B","year":"2004","journal-title":"Eur Heart J"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1007\/s10741-012-9335-x","article-title":"Pericardial syndromes: an update after the ESC guidelines 2004","volume":"18","author":"Seferovic PM","year":"2013","journal-title":"Heart Fail Rev"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"2410","DOI":"10.1056\/NEJMcp1404070","article-title":"Acute Pericarditis","volume":"371","author":"LeWinter MM","year":"2014","journal-title":"N Engl Med"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"341","DOI":"10.3109\/07853890.2010.547212","article-title":"Autoinflammatory diseases and cardiovascular manifestations","volume":"43","author":"Rigante D","year":"2011","journal-title":"Ann Med"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/j.cpcardiol.2011.10.002","article-title":"Pericardial diseases","volume":"37","author":"Dudzinski DM","year":"2012","journal-title":"Curr Probl Cardiol"},{"issue":"4","key":"ref6","doi-asserted-by":"crossref","first-page":"1","DOI":"10.5935\/abc.2013S004","article-title":"I Diretriz Brasileira de Miocardites e Pericardites","volume":"100","author":"Montera MW","year":"2013","journal-title":"Arq Bras Cardiol"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"235","DOI":"10.2459\/JCM.0b013e328351da6e","article-title":"Clinical presentation and long-term follow-up of perimyocarditis","volume":"14","author":"Buiatti A","year":"2013","journal-title":"J Cardiovasc Med (Hagerstown)"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1161\/CIRCULATIONAHA.113.001531","article-title":"Good prognosis for pericarditis with and without myocardial involvement: results from a multicenter, prospective cohort study","volume":"128","author":"Imazio M","year":"2013","journal-title":"Circulation"},{"issue":"11","key":"ref9","doi-asserted-by":"crossref","first-page":"1270","DOI":"10.1161\/CIRCULATIONAHA.111.018580","article-title":"Risk of constrictive pericarditis after acute pericarditis","volume":"124","author":"Imazio M","year":"2011","journal-title":"Circulation"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"1026","DOI":"10.1016\/j.amjcard.2007.04.047","article-title":"Prognosis of idiopathic recurrent pericarditis as determined from previously published reports","volume":"100","author":"Imazio M","year":"2007","journal-title":"Am J Cardiol"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"1522","DOI":"10.1056\/NEJMoa1208536","article-title":"A randomized trial of colchicine for acute pericarditis","volume":"369","author":"Imazio M","year":"2013","journal-title":"N Engl J Med"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"2739","DOI":"10.1161\/CIRCULATIONAHA.106.662114","article-title":"Indicators of poor prognosis of acute pericarditis","volume":"115","author":"Imazio M","year":"2007","journal-title":"Circulation"},{"key":"ref13","doi-asserted-by":"crossref","first-page":"1092","DOI":"10.1161\/CIRCULATIONAHA.110.986372","article-title":"Prevalence of C-reactive protein elevation and time course of normalization in acute pericarditis: implications for the diagnosis, therapy, and prognosis of pericarditis","volume":"123","author":"Imazio M","year":"2011","journal-title":"Circulation"},{"issue":"16","key":"ref14","doi-asserted-by":"crossref","first-page":"1723","DOI":"10.1161\/CIRCULATIONAHA.111.066365","article-title":"Treatment of acute and recurrent idiopathic pericarditis","volume":"127","author":"Lilly LS","year":"2013","journal-title":"Circulation"},{"issue":"6","key":"ref15","doi-asserted-by":"crossref","first-page":"672","DOI":"10.1016\/j.jbspin.2006.03.006","article-title":"Colchicine today","volume":"73","author":"Niel E","year":"2006","journal-title":"Joint Bone Spine"},{"issue":"3","key":"ref16","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1007\/s11926-002-0073-2","article-title":"Update on colchicine and its mechanism of action","volume":"4","author":"Molad Y","year":"2002","journal-title":"Curr Rheumatol Rep"},{"key":"ref17","doi-asserted-by":"crossref","first-page":"409","DOI":"10.7326\/0003-4819-155-7-201110040-00359","article-title":"Colchicine for recurrent pericarditis (CORP): a randomized trial","volume":"155","author":"Imazio M","year":"2011","journal-title":"Ann Intern Med"},{"key":"ref18","doi-asserted-by":"crossref","first-page":"1042","DOI":"10.1016\/j.jacc.2003.09.055","article-title":"Day-hospital treatment of acute pericarditis: a management program for outpatient therapy","volume":"43","author":"Imazio M","year":"2004","journal-title":"J Am Coll Cardiol"},{"key":"ref19","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1016\/j.amjcard.2006.01.086","article-title":"Long-term outcomes in difficult-totreat patients with recurrent pericarditis","volume":"98","author":"Brucato A","year":"2006","journal-title":"Am J Cardiol"},{"key":"ref20","doi-asserted-by":"crossref","first-page":"667","DOI":"10.1161\/CIRCULATIONAHA.107.761064","article-title":"Corticosteroids for recurrent pericarditis: high versus low doses: a nonrandomized observation","volume":"118","author":"Imazio M","year":"2008","journal-title":"Circulation"},{"issue":"3","key":"ref21","first-page":"477","article-title":"Azathioprine in isolated recurrent pericarditis: a single centre experience","volume":"147","author":"Vianello F","year":"2011","journal-title":"nt J Cardiol"},{"key":"ref22","doi-asserted-by":"crossref","first-page":"1062","DOI":"10.1016\/j.mayocp.2012.05.024","article-title":"Pericardiectomy vs medical management in patients with relapsing pericarditis","volume":"87","author":"Khandaker MH","year":"2012","journal-title":"Mayo Clin Proc"},{"key":"ref23","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1159\/000324309","article-title":"The role of the immunogenetic background in the development and recurrence of acute idiopathic pericarditis","volume":"118","author":"Lazaros G","year":"2011","journal-title":"Cardiology"}],"container-title":["Revista da Associa\u00e7\u00e3o M\u00e9dica Brasileira"],"original-title":[],"link":[{"URL":"http:\/\/www.scielo.br\/pdf\/ramb\/v61n2\/0104-4230-ramb-61-02-0184.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,5,22]],"date-time":"2017-05-22T22:58:54Z","timestamp":1495493934000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.scielo.br\/scielo.php?script=sci_arttext&pid=S0104-42302015000200184&lng=en&tlng=en"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,4]]},"references-count":23,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2015,4]]}},"alternative-id":["S0104-42302015000200184"],"URL":"https:\/\/doi.org\/10.1590\/1806-9282.61.02.184","relation":{},"ISSN":["0104-4230"],"issn-type":[{"value":"0104-4230","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,4]]}}}