{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T09:14:02Z","timestamp":1762506842343},"reference-count":20,"publisher":"FapUNIFESP (SciELO)","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rev. Assoc. Med. Bras."],"published-print":{"date-parts":[[2016,7]]},"abstract":"<jats:p>Summary Objective: To describe the values of non-HDL cholesterol (NHDL-c) and the frequency of a family history of early cardiovascular disease (family HCVD) in healthy prepubescent children. Analyze the association between NHDL-c and family HCVD, and possible associations with other risk factors for cardiovascular disease (CVD). Method: Cross-sectional study including 269 prepubescent (aged 6-10 years) schoolchildren with a normal body mass index (+1SD&lt;BMI&gt;-2SD). Data collected: Family HCVD; weight and height, waist circumference and systemic blood pressure; lipid profile (total cholesterol TC, HDL-c, triglycerides and LDL-c), NHDL-c calculation (CT-HDL-c, cut-off = 145 mg\/dL) and insulin resistance (HOMA-IR). Results: High levels were found for NHDL-c in 10 (3.7%) of these schoolchildren, and family early HCVD was found in 46 (17.1%) of them. There was a weak association between family HCVD and NHDL-c (Cramer\u2019s-V-test = 0.120; p=0.050). Among the children with NHDL-c\u2265145 mg\/dL, 4 (40%) have family HCVD. The presence of family HCVD was not associated with the variables being studied. The variables independently associated with NHDL-c \u2265 145 mg\/dL were: HOMA-IR (OR=1.7; 95CI 1.1-2.6) and diastolic blood pressure (OR=1.1; 95CI 1.02-1.2). Conclusion: NHDL-c values were associated with blood pressure and insulin resistance. Family HCVD was not associated with other classic risk factors for CVD, even though the frequency found was five times higher than that of high NHDL-c.<\/jats:p>","DOI":"10.1590\/1806-9282.62.04.347","type":"journal-article","created":{"date-parts":[[2016,7,16]],"date-time":"2016-07-16T13:34:52Z","timestamp":1468676092000},"page":"347-352","source":"Crossref","is-referenced-by-count":6,"title":["Family history of cardiovascular disease and non-HDL cholesterol in prepubescent non-obese children"],"prefix":"10.1590","volume":"62","author":[{"given":"Maria Wany Louzada","family":"Strufaldi","sequence":"first","affiliation":[{"name":"Universidade Federal de S\u00e3o Paulo, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fab\u00edola Isabel Suano de","family":"Souza","sequence":"additional","affiliation":[{"name":"Universidade Federal de S\u00e3o Paulo, Brazil; Faculdade de Medicina do ABC, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rosana Fiorini","family":"Puccini","sequence":"additional","affiliation":[{"name":"Unifesp, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria do Carmo Pinho","family":"Franco","sequence":"additional","affiliation":[{"name":"Unifesp, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"530","reference":[{"key":"ref1","series-title":"Global atlas on cardiovascular disease prevention and control","author":"Mendis S","year":"2011"},{"key":"ref2","series-title":"Indicadores Sociodemogr\u00e1ficos de Sa\u00fade no Brasil","year":"2009"},{"issue":"23","key":"ref3","doi-asserted-by":"crossref","first-page":"1650","DOI":"10.1056\/NEJM199806043382302","article-title":"Association between multiple cardiovascular risk factors and atherosclerosis in children and young adults. 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