{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,28]],"date-time":"2026-01-28T20:46:16Z","timestamp":1769633176785,"version":"3.49.0"},"reference-count":20,"publisher":"FapUNIFESP (SciELO)","issue":"11","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rev. Assoc. Med. Bras."],"abstract":"<jats:p>SUMMARY  OBJECTIVE: This study retrospectively reviewed 46 cases of gastric gastrointestinal stromal tumors treated by endoluminal endoscopic full-thickness resection (EFR) microsurgery in our gastrointestinal endoscopy center. We aimed to evaluate the EFR for the treatment of gastric gastrointestinal stromal tumors originating from the muscularis propria.  METHODS: A total of 46 patients with gastric gastrointestinal stromal tumors originated from the muscularis propria layer from January 2012 to June 2015 were treated with EFR. The patients were followed up with gastroscope and computed tomography (CT) for evaluation of therapeutic effect and safety.  RESULTS: EFR was successfully accomplished to remove all tumors in 46 patients. The mean procedure time was 82.5\u00b139.8min (56-188min). Except in 3 leiomyomas, pathological examination confirmed gastrointestinal stromal tumor (GIST) in 43 cases. None of the patients had occurred bleeding, peritonitis and other complications after EFR. Thereafter, all patients were followed up with gastro-scope after 1, 6,12 months.  CONCLUSIONS: EFR is effective and safe for patients with gastric gastrointestinal stromal tumors originated from muscularis propria layer and has the advantage of less invasive treatment and higher tumor resection rate. It should be considered for further application.<\/jats:p>","DOI":"10.1590\/1806-9282.64.11.1002","type":"journal-article","created":{"date-parts":[[2018,12,15]],"date-time":"2018-12-15T13:49:03Z","timestamp":1544881743000},"page":"1002-1006","source":"Crossref","is-referenced-by-count":13,"title":["Endoscopic full-thickness resection for gastric gastrointestinal stromal tumor originating from the muscularis propria"],"prefix":"10.1590","volume":"64","author":[{"given":"Ju","family":"Huang","sequence":"first","affiliation":[{"name":"Nanchang University,  China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8547-8067","authenticated-orcid":false,"given":"Xiang-Shu","family":"Xian","sequence":"additional","affiliation":[{"name":"The Affiliated Yantai Yuhuangding Hospital of Qingdao University,  China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Liu-Ye","family":"Huang","sequence":"additional","affiliation":[{"name":"The Affiliated Yantai Yuhuangding Hospital of Qingdao University,  China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bo","family":"Zhang","sequence":"additional","affiliation":[{"name":"The Affiliated Yantai Yuhuangding Hospital of Qingdao University,  China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cheng-Rong","family":"Wu","sequence":"additional","affiliation":[{"name":"The Affiliated Yantai Yuhuangding Hospital of Qingdao University,  China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jun","family":"Cui","sequence":"additional","affiliation":[{"name":"The Affiliated Yantai Yuhuangding Hospital of Qingdao University,  China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"530","published-online":{"date-parts":[[2018,11]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"S39","DOI":"10.1016\/S0959-8049(02)80602-5","article-title":"Pathology and diagnostic criteria of gastrointestinal stromal tumors (GISTs): a review","volume":"38","author":"Miettinen M","year":"2002","journal-title":"Eur J Cancer"},{"issue":"18","key":"ref2","doi-asserted-by":"crossref","first-page":"3898","DOI":"10.1200\/JCO.2002.03.095","article-title":"Prognostic value of KIT mutation type, mitotic activity, and histologic subtype in gastrointestinal stromal tumors","volume":"20","author":"Singer S","year":"2002","journal-title":"J Clin Oncol"},{"issue":"24","key":"ref3","doi-asserted-by":"crossref","first-page":"3316","DOI":"10.3748\/wjg.v13.i24.3316","article-title":"Therapeutic procedures for submucosal tumors in the gastrointestinal tract","volume":"13","author":"Ponsaing LG","year":"2007","journal-title":"World J Gastroenterol"},{"issue":"26","key":"ref4","doi-asserted-by":"crossref","first-page":"3465","DOI":"10.3748\/wjg.v18.i26.3465","article-title":"Endoscopic therapy for gastric stromal tumors originating from the muscularis propria","volume":"18","author":"Huang LY","year":"2012","journal-title":"World J Gastroenterol"},{"issue":"25","key":"ref5","doi-asserted-by":"crossref","first-page":"8253","DOI":"10.3748\/wjg.v20.i25.8253","article-title":"Endoscopic full-thickness resection and laparoscopic surgery for treatment of gastric stromal tumors","volume":"20","author":"Huang LY","year":"2014","journal-title":"World J Gastroenterol"},{"issue":"1","key":"ref6","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1097\/00000658-200001000-00008","article-title":"Two hundred gastrointestinal stromal tumors: recurrence patterns and prognostic factors for survival","volume":"231","author":"DeMatteo RP","year":"2000","journal-title":"Ann Surg"},{"issue":"11","key":"ref7","doi-asserted-by":"crossref","first-page":"655","DOI":"10.1016\/S1470-2045(02)00899-9","article-title":"Management of malignant gastrointestinal stromal tumours","volume":"3","author":"Joensuu H","year":"2002","journal-title":"Lancet Oncol"},{"issue":"1","key":"ref8","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/j.gie.2010.09.016","article-title":"Evaluation of a new multitasking platform for endoscopic full-thickness resection","volume":"73","author":"Ikeda K","year":"2011","journal-title":"Gastrointest Endosc"},{"issue":"2","key":"ref9","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1007\/s00464-010-1189-5","article-title":"Full-thickness endoscopic resection of nonintracavitary gastric stromal tumors: a novel approach","volume":"25","author":"Wang L","year":"2011","journal-title":"Surg Endosc"},{"issue":"1","key":"ref10","doi-asserted-by":"crossref","first-page":"18","DOI":"10.3892\/mco.2014.412","article-title":"Establishment of the hybrid endoscopic full-thickness resection of gastric gastrointestinal stromal tumors","volume":"3","author":"Mori H","year":"2015","journal-title":"Mol Clin Oncol"},{"issue":"6","key":"ref11","doi-asserted-by":"crossref","first-page":"1082","DOI":"10.1016\/j.gie.2009.12.036","article-title":"Endoscopic mucosal resection with full-thickness closure for difficult polyps: a prospective clinical trial","volume":"71","author":"Agrawal D","year":"2010","journal-title":"Gastrointest Endosc"},{"issue":"6","key":"ref12","doi-asserted-by":"crossref","first-page":"1146","DOI":"10.1016\/j.gie.2009.05.015","article-title":"Endoluminal compression clip: full-thickness resection of the mesenteric bowel wall in a porcine model","volume":"70","author":"Kopelman Y","year":"2009","journal-title":"Gastrointest Endosc"},{"issue":"11","key":"ref13","doi-asserted-by":"crossref","first-page":"3141","DOI":"10.1007\/s00464-012-2305-5","article-title":"Endoscopic muscularis dissection for upper gastrointestinal subepithelial tumors originating from the muscularis propria","volume":"26","author":"Liu BR","year":"2012","journal-title":"Surg Endosc"},{"issue":"6","key":"ref14","doi-asserted-by":"crossref","first-page":"1369","DOI":"10.1016\/j.gie.2011.07.057","article-title":"Efficacy of full-thickness GI perforation closure with a novel over-the-scope clip application device: an animal study","volume":"74","author":"Matthes K","year":"2011","journal-title":"Gastrointest Endosc"},{"issue":"4","key":"ref15","doi-asserted-by":"crossref","first-page":"610","DOI":"10.1016\/j.gie.2014.03.049","article-title":"International multicenter experience with an over-the-scope clipping device for endoscopic management of GI defects (with video)","volume":"80","author":"Haito-Chavez Y","year":"2014","journal-title":"Gastrointest Endosc"},{"issue":"24","key":"ref16","doi-asserted-by":"crossref","first-page":"7767","DOI":"10.3748\/wjg.v20.i24.7767","article-title":"Novel treatment options for perforations of the upper gastrointestinal tract: endoscopic vacuum therapy and over-the-scope clips","volume":"20","author":"Mennigen R","year":"2014","journal-title":"World J Gastroenterol"},{"issue":"2","key":"ref17","doi-asserted-by":"crossref","first-page":"524","DOI":"10.1007\/s00464-013-3197-8","article-title":"Submucosal tunneling endoscopic resection for small upper gastrointestinal subepithelial tumors originating from the muscularis propria layer","volume":"28","author":"Ye LP","year":"2014","journal-title":"Surg Endosc"},{"issue":"2","key":"ref18","doi-asserted-by":"crossref","first-page":"468","DOI":"10.1007\/s00464-010-1195-7","article-title":"Endoscopic enucleation for gastric subepithelial tumors originating in the muscularis propria layer","volume":"25","author":"Jeong ID","year":"2011","journal-title":"Surg Endosc"},{"issue":"3","key":"ref19","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1089\/lap.2013.0370","article-title":"Endolumenal endoscopic full-thickness resection of muscularis propria-originating gastric submucosal tumors","volume":"24","author":"Feng Y","year":"2014","journal-title":"J Laparoendosc Adv Surg Tech A"},{"issue":"7","key":"ref20","doi-asserted-by":"crossref","first-page":"1546","DOI":"10.1007\/s00464-009-0395-5","article-title":"Endoscopic submucosal dissection for colorectal epithelial neoplasm","volume":"23","author":"Zhou PH","year":"2009","journal-title":"Surg Endosc"}],"container-title":["Revista da Associa\u00e7\u00e3o M\u00e9dica Brasileira"],"original-title":[],"link":[{"URL":"http:\/\/www.scielo.br\/pdf\/ramb\/v64n11\/1806-9282-ramb-64-11-1002.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2018,12,26]],"date-time":"2018-12-26T13:02:42Z","timestamp":1545829362000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.scielo.br\/scielo.php?script=sci_arttext&pid=S0104-42302018001101002&lng=en&tlng=en"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,11]]},"references-count":20,"journal-issue":{"issue":"11","published-online":{"date-parts":[[2018,11]]}},"alternative-id":["S0104-42302018001101002"],"URL":"https:\/\/doi.org\/10.1590\/1806-9282.64.11.1002","relation":{},"ISSN":["1806-9282","0104-4230"],"issn-type":[{"value":"1806-9282","type":"electronic"},{"value":"0104-4230","type":"print"}],"subject":[],"published":{"date-parts":[[2018,11]]}}}