{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,17]],"date-time":"2026-01-17T02:17:20Z","timestamp":1768616240664,"version":"3.49.0"},"reference-count":47,"publisher":"FapUNIFESP (SciELO)","issue":"2","license":[{"start":{"date-parts":[[2019,2,1]],"date-time":"2019-02-01T00:00:00Z","timestamp":1548979200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2019,2,1]],"date-time":"2019-02-01T00:00:00Z","timestamp":1548979200000},"content-version":"am","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2019,2,1]],"date-time":"2019-02-01T00:00:00Z","timestamp":1548979200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rev. Assoc. Med. Bras."],"abstract":"<jats:p>SUMMARY Individuals with Lactose Intolerance (LI) tend to exclude milk from their diet since this behavior seems to relieve the symptoms caused by the disease. However, milk is a food of high nutritional value, and complete exclusion of dairy products may favor the development of bone diseases such as osteopenia and osteoporosis. The objective of this review was to evaluate the scientific evidence on the adequate management of patients with LI. This study was carried out from the review of the scientific literature in PubMed and SciELO databases. Complete exclusion of conventional dairy products is not necessary since most individuals with LI can tolerate up to 12 grams of lactose daily in a single dose. Yogurts and cheeses matured for having low amounts of lactose are part of the strategy that allows consumption of dairy products by patients with LI. Currently, there is a diversity of products considered as \u201cmilk substitutes\u201d and supplements aimed at individuals with LI. However, these strategies still require better-designed studies.<\/jats:p>","DOI":"10.1590\/1806-9282.65.2.270","type":"journal-article","created":{"date-parts":[[2019,3,16]],"date-time":"2019-03-16T16:27:35Z","timestamp":1552753655000},"page":"270-275","source":"Crossref","is-referenced-by-count":15,"title":["Lactose intolerance: what is a correct management?"],"prefix":"10.1590","volume":"65","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3200-5343","authenticated-orcid":false,"given":"Geisa J.","family":"Santos","sequence":"first","affiliation":[{"name":"Federal University of Bahia,  Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2687-2080","authenticated-orcid":false,"given":"Raquel","family":"Rocha","sequence":"additional","affiliation":[{"name":"Federal University of Bahia,  Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5936-9791","authenticated-orcid":false,"given":"Genoile O.","family":"Santana","sequence":"additional","affiliation":[{"name":"State University of Bahia,  Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"530","published-online":{"date-parts":[[2019,2]]},"reference":[{"issue":"8","key":"ref1","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1093\/qjmed\/hcq082","article-title":"Lactose malabsorption and intolerance: a systematic review of the diagnostic value of gastrointestinal symptoms and self-reported milk intolerance","volume":"103","author":"Jellema P","year":"2010","journal-title":"QJM."},{"issue":"4","key":"ref2","first-page":"335","article-title":"An\u00e1lise molecular da hipolactasia prim\u00e1ria do tipo adulto: uma nova vis\u00e3o do diagn\u00f3stico de um problema antigo e frequente","volume":"57","author":"Wortmann AC","year":"2013","journal-title":"Rev AMRIGS."},{"issue":"2","key":"ref3","first-page":"1","article-title":"NIH consensus development conference statement: lactose intolerance and health","volume":"27","author":"Suchy FJ","year":"2010","journal-title":"NIH Consens State Sci Statements."},{"issue":"1","key":"ref4","first-page":"5","article-title":"Aspectos hist\u00f3ricos, fisiol\u00f3gicos e antropos\u00f3ficos do leite na alimenta\u00e7\u00e3o humana: uma introdu\u00e7\u00e3o ao tema","volume":"34","author":"Benevides IA","year":"2014","journal-title":"Arte M\u00e9d Ampl."},{"key":"ref5","series-title":"Milk and dairy products in human nutrition","year":"2013"},{"issue":"5","key":"ref6","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1590\/S1415-52732012000500004","article-title":"Ingest\u00e3o de c\u00e1lcio e densidade mineral \u00f3ssea em mulheres adultas intolerantes \u00e0 lactose","volume":"25","author":"Salom\u00e3o NA","year":"2012","journal-title":"Rev Nutr."},{"issue":"2","key":"ref7","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1111\/j.1365-2036.2007.03557.x","article-title":"Review article: lactose intolerance in clinical practice-myths and realities","volume":"27","author":"Lomer MC","year":"2008","journal-title":"Aliment Pharmacol Ther."},{"issue":"2","key":"ref8","doi-asserted-by":"crossref","first-page":"187","DOI":"10.3748\/wjg.v12.i2.187","article-title":"Management and treatment of lactose malabsorption","volume":"12","author":"Montalto M","year":"2006","journal-title":"World J Gastroenterol."},{"issue":"5","key":"ref9","doi-asserted-by":"crossref","first-page":"632","DOI":"10.1136\/gut.41.5.632","article-title":"Improved clinical tolerance to chronic lactose ingestion in subjects with lactose intolerance: a placebo effect?","volume":"41","author":"Briet F","year":"1997","journal-title":"Gut."},{"issue":"5","key":"ref10","first-page":"212","article-title":"Lactose malabsorption in patients with inflammatory bowel disease without activity: would it be necessary to exclude lactose products in the diet of all patients?","volume":"21","author":"Ba\u00f1os Madrid R","year":"2004","journal-title":"A Med Intern."},{"issue":"5","key":"ref11","doi-asserted-by":"crossref","first-page":"852","DOI":"10.1590\/S0004-27302006000500005","article-title":"Biodisponibilidade do c\u00e1lcio diet\u00e9tico","volume":"50","author":"Buzinaro EF","year":"2006","journal-title":"Arq Bras Endocrinol Metab."},{"issue":"3","key":"ref12","first-page":"143","article-title":"Aspectos da absor\u00e7\u00e3o no metabolismo do c\u00e1lcio e vitamina D","volume":"37","author":"Gr\u00fcdtner VS","year":"1997","journal-title":"Rev Bras Reumatol."},{"key":"ref13","series-title":"Pir\u00e2mide dos alimentos. 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