{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,4]],"date-time":"2026-09-04T22:29:56Z","timestamp":1788560996358,"version":"build-2803163510"},"reference-count":24,"publisher":"FapUNIFESP (SciELO)","issue":"1","license":[{"start":{"date-parts":[[2020,1,1]],"date-time":"2020-01-01T00:00:00Z","timestamp":1577836800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2020,1,1]],"date-time":"2020-01-01T00:00:00Z","timestamp":1577836800000},"content-version":"am","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2020,1,1]],"date-time":"2020-01-01T00:00:00Z","timestamp":1577836800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rev. Assoc. Med. Bras."],"abstract":"<jats:p>SUMMARY  OBJECTIVES  Individuals living with HIV seem to be more prone to changes in the redistribution of body fat, characterized as lipodystrophy, which may occur in conjunction with metabolic diseases. In the present study, such impacts were assessed in adults with and without HIV and associated with the time of virus diagnosis and treatment with antiretroviral.  METHODS  A cross-sectional study with 123 adults, in which 87 had HIV and 36 without HIV, of both sexes, in outpatient follow-up at the Specialized Care Service (SAE) in Maca\u00e9-RJ. The following were made: 1) Alteration in body fat distribution, measured by anthropometric parameters and self-reported lipodystrophy; 2) Biochemical profile; 3) Association between HIV diagnosis time and antiretroviral treatment.  RESULTS  54.47% (n = 67) males, 45.52% (n = 56) females, mean age 37 years. Of these 87 were people living with HIV, 29% (n = 25) had self-reported lipodystrophy, mean time of virus infection, and antiretroviral treatment (5.80 \u00b1 4.56 and 5.14 \u00b1 3.82 years), respectively. Patients with self-reported lipodystrophy had a greater change in body fat distribution between 3-6 years of HIV diagnosis and a negative cholesterol profile. The antiretroviral treatment time influenced total cholesterol and triglycerides, even for patients without self-reported lipodystrophy, with a further nine years under treatment.  CONCLUSION  In this study, the negative cholesterol profile was mainly related to antiretroviral treatment time, even for patients without self-reported lipodystrophy, and changes in body fat distribution, measured by anthropometry, was especially associated with time for HIV infection in those with lipodystrophy self-reported.<\/jats:p>","DOI":"10.1590\/1806-9282.66.1.67","type":"journal-article","created":{"date-parts":[[2020,2,25]],"date-time":"2020-02-25T15:34:08Z","timestamp":1582644848000},"page":"67-73","source":"Crossref","is-referenced-by-count":5,"title":["Association between changes in body fat distribution, biochemical profile, time of HIV diagnosis, and antiretroviral treatment in adults living with and without virus infection"],"prefix":"10.1590","volume":"66","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2873-077X","authenticated-orcid":false,"given":"Lismeia Raimundo","family":"Soares","sequence":"first","affiliation":[{"name":"UFRJaneiro,  Brasil; FMABC,  Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5216-0100","authenticated-orcid":false,"given":"Gabriella Coelho","family":"Menezes","sequence":"additional","affiliation":[{"name":"UFRJ,  Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8362-2953","authenticated-orcid":false,"given":"Ana Paula Menna","family":"Barreto","sequence":"additional","affiliation":[{"name":"UFRJ,  Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9462-0213","authenticated-orcid":false,"given":"M\u00f4nica de Souza Lima","family":"Sant\u2019Anna","sequence":"additional","affiliation":[{"name":"UFRJ,  Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5377-5983","authenticated-orcid":false,"given":"Nadir Machado Alves","family":"Cardoso","sequence":"additional","affiliation":[{"name":"Departamento de Vigil\u00e2ncia, Preven\u00e7\u00e3o e Controle das IST, do HIV\/AIDS e das Hepatites Virais,  Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4553-2559","authenticated-orcid":false,"given":"Jorge Sim\u00e3o do Ros\u00e1rio","family":"Casseb","sequence":"additional","affiliation":[{"name":"USP,  Brasil; USP,  Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1223-1589","authenticated-orcid":false,"given":"Fernando Luiz Affonso","family":"Fonseca","sequence":"additional","affiliation":[{"name":"Unifesp,  Brasil; FMABC,  Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"530","published-online":{"date-parts":[[2020,1]]},"reference":[{"key":"ref1","series-title":"Report on the globalAIDS Epidemic - Overview of the global AIDS Epidemic","year":"2018"},{"issue":"4","key":"ref2","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1111\/hiv.12421","article-title":"Life expectancy of HIV-positive people after starting combination antiretroviral therapy: a meta-analysis","volume":"18","author":"Teeraananchai S","year":"2017","journal-title":"HIV Med"},{"issue":"3","key":"ref3","first-page":"209","article-title":"Perfil nutricional e m\u00e9todos de avalia\u00e7\u00e3o do estado nutricional de pacientes infectados pelo HIV","volume":"32","author":"Pires DS","year":"2017","journal-title":"BRASPEN J"},{"issue":"8","key":"ref4","doi-asserted-by":"crossref","first-page":"1133","DOI":"10.1086\/586713","article-title":"Major clinical outcomes in antiretroviral therapy (ART)\u2013naive participants and in those not receiving ART at baseline in the SMART study","volume":"197","author":"Emery S","year":"2008","journal-title":"J Infect Dis"},{"key":"ref5","series-title":"Perfil antropom\u00e9trico e correla\u00e7\u00e3o entre diferentes medidas relativas \u00e0 composi\u00e7\u00e3o corporal e a distribui\u00e7\u00e3o da gordura relacionados ao risco cardiovascular em indiv\u00edduos adultos vivendo com HIV\/AIDS","author":"Soares LR","year":"2010"},{"key":"ref6","series-title":"HIV\/AIDS, hepatites e outras DST. 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