{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,14]],"date-time":"2026-11-14T14:32:21Z","timestamp":1794666741656,"version":"4.9.1"},"reference-count":15,"publisher":"FapUNIFESP (SciELO)","issue":"10","license":[{"start":{"date-parts":[[2020,10,1]],"date-time":"2020-10-01T00:00:00Z","timestamp":1601510400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2020,10,1]],"date-time":"2020-10-01T00:00:00Z","timestamp":1601510400000},"content-version":"am","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2020,10,1]],"date-time":"2020-10-01T00:00:00Z","timestamp":1601510400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rev. Assoc. Med. Bras."],"abstract":"<jats:p>SUMMARY  INTRODUCTION: The present study aimed to determine independent predictors of left atrial thrombus (LAT) in acute ischemic stroke (AIS) patients without atrial fibrillation (AF) using transesophageal echocardiography (TEE).  METHODS: In this single-center, retrospective study, we enrolled 149 consecutive AIS patients. All of the patients underwent a TEE examination to detect LAT within 10 days following admission. Multivariate logistic regression analysis was performed to assess independent predictors of LAT.  RESULTS: Among all cases, 14 patients (9.3%) had a diagnosis of LAT based on the TEE examination. In a multivariate analysis, elevated mean platelet volume (MPV), low left-ventricle ejection fraction (EF), creatinine, and reduced left-atrium appendix (LAA) peak emptying velocity were independent predictors of LAT. The area under the receiver operating characteristic curve analysis for MPV was 0.70 (95%CI: 0.57-0.83; p = 0.011). With the optimal cut-off value of 9.45, MPV had a sensitivity of 71.4% and a specificity of 63% to predict LAT.  CONCLUSION: AIS patients with low ventricle EF and elevated MPV should undergo further TEE examination to verify the possibility of a cardio-embolic source. In addition, this research may provide novel information with respect to the applicability of MPV to predict LAT in such patients without AF.<\/jats:p>","DOI":"10.1590\/1806-9282.66.10.1437","type":"journal-article","created":{"date-parts":[[2020,11,6]],"date-time":"2020-11-06T14:28:00Z","timestamp":1604672880000},"page":"1437-1443","source":"Crossref","is-referenced-by-count":20,"title":["Predictors of left atrial thrombus in acute ischemic stroke patients without atrial fibrillation: A single-center cross-sectional study"],"prefix":"10.1590","volume":"66","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8188-5020","authenticated-orcid":false,"given":"Tufan","family":"Cinar","sequence":"first","affiliation":[{"name":"Health Science University,  Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6515-7349","authenticated-orcid":false,"given":"Mert \u0130lker","family":"Hayiro\u011flu","sequence":"additional","affiliation":[{"name":"Health Science University,  Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3763-0570","authenticated-orcid":false,"given":"Vedat","family":"\u00c7i\u00e7ek","sequence":"additional","affiliation":[{"name":"Health Science University,  Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3709-2506","authenticated-orcid":false,"given":"S\u00fcha","family":"Asal","sequence":"additional","affiliation":[{"name":"Health Science University,  Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2048-4930","authenticated-orcid":false,"given":"Murat Mert","family":"Atmaca","sequence":"additional","affiliation":[{"name":"Health Science University,  Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6482-9913","authenticated-orcid":false,"given":"Nurg\u00fcl","family":"Keser","sequence":"additional","affiliation":[{"name":"Health Science University,  Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8617-3281","authenticated-orcid":false,"given":"Ahmet L\u00fctfullah","family":"Orhan","sequence":"additional","affiliation":[{"name":"Health Science University,  Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"530","published-online":{"date-parts":[[2020,10]]},"reference":[{"key":"ref1","first-page":"3238165","article-title":"Stroke in the 21st century: a snapshot of the burden, epidemiology, and quality of life","volume":"2018","author":"Donkor ES","year":"2018","journal-title":"Stroke Res Treat"},{"issue":"1","key":"ref2","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1161\/01.STR.24.1.35","article-title":"Classification of subtype of acute ischemic stroke. 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