{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,18]],"date-time":"2026-10-18T02:16:33Z","timestamp":1792289793576,"version":"4.4.0"},"reference-count":13,"publisher":"FapUNIFESP (SciELO)","issue":"2","license":[{"start":{"date-parts":[[2020,2,1]],"date-time":"2020-02-01T00:00:00Z","timestamp":1580515200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2020,2,1]],"date-time":"2020-02-01T00:00:00Z","timestamp":1580515200000},"content-version":"am","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2020,2,1]],"date-time":"2020-02-01T00:00:00Z","timestamp":1580515200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rev. Assoc. Med. Bras."],"abstract":"<jats:p>SUMMARY Goiter is a localized or generalized thyroid hypertrophy. It can remain within the cervical region or grow down until it invades the mediastinum. The signs and symptoms depend on the size and location of the goiter. Although drugs and radioactive iodine are often used to treat thyroid disease, the presence of symptomatic substernal goiter is a clear indication for surgery. Death or postoperative complications rarely occur. We present a case of a 71-year-old man with recurrent thyroid pathology in the form of substernal goiter and hyperthyroidism even after partial thyroidectomy. The importance of this relates to the clinical evolution, volume, and location of the goiter as well as the surgical and pharmacological approach.<\/jats:p>","DOI":"10.1590\/1806-9282.66.2.109","type":"journal-article","created":{"date-parts":[[2020,5,19]],"date-time":"2020-05-19T23:14:37Z","timestamp":1589930077000},"page":"109-111","source":"Crossref","is-referenced-by-count":3,"title":["Substernal Goiter: a case to remember"],"prefix":"10.1590","volume":"66","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5152-7505","authenticated-orcid":false,"given":"Sara Sim\u00f5es","family":"Macedo","sequence":"first","affiliation":[{"name":"Centro Hospitalar Tondela-Viseu,E.P.E,  Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7179-7542","authenticated-orcid":false,"given":"M\u00f3nica","family":"Teixeira","sequence":"additional","affiliation":[{"name":"Centro Hospitalar Tondela-Viseu,E.P.E,  Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7472-7665","authenticated-orcid":false,"given":"Andreia","family":"Correia","sequence":"additional","affiliation":[{"name":"Centro Hospitalar Tondela-Viseu,E.P.E,  Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0245-6186","authenticated-orcid":false,"given":"C\u00e1tia","family":"Cabral","sequence":"additional","affiliation":[{"name":"Hospital Trofa Sa\u00fade Vila Real,  Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"530","published-online":{"date-parts":[[2020,2]]},"reference":[{"issue":"11","key":"ref1","first-page":"860","article-title":"The plunging goiter: about 43 cases","volume":"89","author":"Zainine R","year":"2011","journal-title":"Tunis Med"},{"issue":"872","key":"ref2","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1136\/pgmj.74.872.327","article-title":"Compression syndromes caused by substernal goitres","volume":"74","author":"Anders HJ","year":"1998","journal-title":"Postgrad Med J"},{"issue":"10","key":"ref3","doi-asserted-by":"crossref","first-page":"1420","DOI":"10.1002\/hed.21617","article-title":"Substernal goiters: incidence, surgical approach, and complications in a tertiary care referral center","volume":"33","author":"Raffaelli M","year":"2011","journal-title":"Head Neck"},{"issue":"2","key":"ref4","first-page":"224","article-title":"Substernal goiter: an unusual cause of respiratory failure after coronary artery bypass grafting","volume":"32","author":"Cagli K","year":"2005","journal-title":"Tex Heart Inst J"},{"issue":"5","key":"ref5","doi-asserted-by":"crossref","first-page":"524","DOI":"10.5761\/atcs.cr.10.01628","article-title":"Single-stage operation for giant substernal goiter with severe coronary artery disease","volume":"17","author":"Wexler S","year":"2011","journal-title":"Ann Thorac Cardiovasc Surg"},{"key":"ref6","article-title":"Goitre endothoracique","author":"Daniel C","year":"2000","journal-title":"EMC Pneumol"},{"issue":"3","key":"ref7","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1007\/s00423-015-1288-9","article-title":"Sternotomy for substernal goiter: retrospective study of 52 operations","volume":"400","author":"Rolighed L","year":"2015","journal-title":"Langenbecks Arch Surg"},{"issue":"4","key":"ref8","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1590\/2359-3997000000266","article-title":"Substernal goiter and laryngopharyngeal reflux","volume":"61","author":"Rodrigues MG","year":"2017","journal-title":"Arch Endocrinol Metab"},{"issue":"1","key":"ref9","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/j.anorl.2015.09.007","article-title":"Substernal goiter: experience with 50 cases","volume":"133","author":"Benbakh M","year":"2016","journal-title":"Eur Ann Otorhinolaryngol Head Neck Dis"},{"issue":"3","key":"ref10","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1016\/S0030-6665(20)31264-0","article-title":"Surgery for benign thyroid disease causing tracheoesophageal compression","volume":"23","author":"Shaha AR","year":"1990","journal-title":"Otolaryngol Clin North Am"},{"issue":"3","key":"ref11","doi-asserted-by":"crossref","first-page":"480","DOI":"10.1016\/j.ejrad.2008.03.030","article-title":"Computed tomography and magnetic resonance imaging in diseases of the thyroid and parathyroid","volume":"66","author":"Kabala JE","year":"2008","journal-title":"Eur J Radiol"},{"issue":"5","key":"ref12","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1017\/S0022215107000047","article-title":"Sternotomy for substernal goitre: an otolaryngologist\u2019s perspective","volume":"122","author":"Burns P","year":"2008","journal-title":"J Laryngol Otol"},{"issue":"6","key":"ref13","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1016\/0196-0709(94)90081-7","article-title":"Substernal goiter: a clinical review","volume":"15","author":"Singh B","year":"1994","journal-title":"Am J Otolaryngol"}],"container-title":["Revista da Associa\u00e7\u00e3o M\u00e9dica Brasileira"],"original-title":[],"link":[{"URL":"http:\/\/www.scielo.br\/pdf\/ramb\/v66n2\/1806-9282-ramb-66-2-0109.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,1,23]],"date-time":"2021-01-23T18:55:43Z","timestamp":1611428143000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.scielo.br\/scielo.php?script=sci_arttext&pid=S0104-42302020000200109&tlng=en"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,2]]},"references-count":13,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2020,2]]}},"alternative-id":["S0104-42302020000200109"],"URL":"https:\/\/doi.org\/10.1590\/1806-9282.66.2.109","relation":{},"ISSN":["1806-9282","0104-4230"],"issn-type":[{"value":"1806-9282","type":"electronic"},{"value":"0104-4230","type":"print"}],"subject":[],"published":{"date-parts":[[2020,2]]}}}