{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T12:57:21Z","timestamp":1740142641654,"version":"3.37.3"},"reference-count":27,"publisher":"FapUNIFESP (SciELO)","issue":"6","license":[{"start":{"date-parts":[[2020,6,1]],"date-time":"2020-06-01T00:00:00Z","timestamp":1590969600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2020,6,1]],"date-time":"2020-06-01T00:00:00Z","timestamp":1590969600000},"content-version":"am","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2020,6,1]],"date-time":"2020-06-01T00:00:00Z","timestamp":1590969600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rev. Assoc. Med. Bras."],"abstract":"<jats:p>SUMMARY  OBJECTIVE  To study the profile of associated autoimmune diseases in a series of patients with systemic lupus erythematosus (SLE) and see if such associations are linked to IgA deficiency.  METHODS  Two hundred eighty-one patients with SLE were studied for Ig A levels by nephelometry. Levels equal to or under 0.05g\/dL were considered as IgA deficiency. Epidemiological and clinical data, including the presence of associated autoimmune diseases, were extracted from the patient\u2019s charts.  RESULTS  Ig A deficiency was found in 6% of the patients. In 30.2% of SLE patients, there was at least one more autoimmune disease; Hashimoto thyroiditis and Sj\u00f6gren\u2019s syndrome were the most common. No association between the occurrence of associated autoimmune disease with IgA deficiency was found.  CONCLUSIONS  There is a high prevalence of autoimmune diseases associated with SLE. IgA deficiency does not affect the presence of these associations.<\/jats:p>","DOI":"10.1590\/1806-9282.66.6.752","type":"journal-article","created":{"date-parts":[[2020,7,20]],"date-time":"2020-07-20T12:16:18Z","timestamp":1595247378000},"page":"752-756","source":"Crossref","is-referenced-by-count":1,"title":["Serum immunoglobulin a deficiency and autoimmune comorbidities: a crossectional study in 281 patients with systemic lupus erythematosus"],"prefix":"10.1590","volume":"66","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1365-6968","authenticated-orcid":false,"given":"Gustavo Fel\u00edcio Alexandroni","family":"Linzmeyer","sequence":"first","affiliation":[{"name":"Faculdade Evang\u00e9lica Mackenzie,  Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3431-4086","authenticated-orcid":false,"given":"Fabiane Karen","family":"Miyake","sequence":"additional","affiliation":[{"name":"Faculdade Evang\u00e9lica Mackenzie,  Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6310-9789","authenticated-orcid":false,"given":"Thiago Alberto F. 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