{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,29]],"date-time":"2025-10-29T03:49:39Z","timestamp":1761709779344,"version":"3.37.3"},"reference-count":18,"publisher":"FapUNIFESP (SciELO)","issue":"8","license":[{"start":{"date-parts":[[2020,8,1]],"date-time":"2020-08-01T00:00:00Z","timestamp":1596240000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2020,8,1]],"date-time":"2020-08-01T00:00:00Z","timestamp":1596240000000},"content-version":"am","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2020,8,1]],"date-time":"2020-08-01T00:00:00Z","timestamp":1596240000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rev. Assoc. Med. Bras."],"abstract":"<jats:p>SUMMARY  OBJECTIVE  To identify the use of Potentially Inappropriate Medications with imminent risk of Cardiovascular and Cerebrovascular Adverse Events (PIM-CCVAE), in addition to the factors associated with a group of elderly individuals undergoing therapeutic care in a Brazilian public service.  METHODS  A cross-sectional retrospective study conducted at a secondary level service located in Carapicu\u00edba, SP, Brasil. Only elderly individuals (\u226560 years) who were treated in one of the outpatient departments were included. The use of PIM-CCVAE was defined based on the PIM-CCVAEs list. In this research, we used descriptive statistics and logistic regression to identify and track possible predictors of MPI use. All statistical analyses were performed using Stata software version 15.1 (Stata Corporation).  RESULTS  The sample included 233 elderly individuals, with a mean age of 74.9 (\u00b1 9.4) years. Of these, 74.2% used at least one PIM-CCVAE, with an average daily intake of 1.3 (\u00b1 1) PIM\/elderly. The presence of comorbidities, diseases of the circulatory system, polypharmacy, and low to moderate scores in morbidity and mortality were important factors associated with an increased odds ratio for the consumption of PIM-CCVAE. It is also emphasized that the presence of neurological symptoms proved to be a protective factor for this outcome.  CONCLUSION  Given the clinical severity and imminent risk of CCVAE in the researched group, preventive measures should be instituted to minimize health problems related to medication in the public network.<\/jats:p>","DOI":"10.1590\/1806-9282.66.8.1087","type":"journal-article","created":{"date-parts":[[2020,9,11]],"date-time":"2020-09-11T16:56:23Z","timestamp":1599843383000},"page":"1087-1092","source":"Crossref","is-referenced-by-count":4,"title":["Risk factors associated with potential cardiovascular and cerebrovascular adverse events in elderly individuals assisted at secondary level"],"prefix":"10.1590","volume":"66","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9067-8581","authenticated-orcid":false,"given":"Henrique Souza Barros de","family":"Oliveira","sequence":"first","affiliation":[{"name":"Centro Universit\u00e1rio S\u00e3o Camilo,  Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3210-0319","authenticated-orcid":false,"given":"Ana Claudia","family":"Michels","sequence":"additional","affiliation":[{"name":"Centro Universit\u00e1rio S\u00e3o Camilo,  Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1508-5572","authenticated-orcid":false,"given":"Maysa","family":"Nahime","sequence":"additional","affiliation":[{"name":"Hospital Geral de Carapicu\u00edba,  Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2729-2942","authenticated-orcid":false,"given":"Lorena de Melo","family":"Caetano","sequence":"additional","affiliation":[{"name":"Hospital Geral de Carapicu\u00edba,  Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8426-4892","authenticated-orcid":false,"given":"Maria Luiza Galoro","family":"Corradi","sequence":"additional","affiliation":[{"name":"Centro Universit\u00e1rio S\u00e3o Camilo,  Brasil; Hospital Geral de Carapicu\u00edba,  Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"530","published-online":{"date-parts":[[2020,8]]},"reference":[{"year":"2017","series-title":"Cardiovascular diseases (CVDs)","key":"ref1"},{"issue":"1","key":"ref2","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1080\/13814788.2017.1288211","article-title":"Prevalence of inappropriate medication use in residential long-term care facilities for the elderly: a systematic review","volume":"23","author":"Storms H","year":"2017","journal-title":"Eur J Gen Pract"},{"issue":"2","key":"ref3","first-page":"165","article-title":"Pharmacological aspects of elderly: an integrative literature review","volume":"97","author":"Oliveira HSB","year":"2018","journal-title":"Rev Med (S\u00e3o 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