{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,6,17]],"date-time":"2025-06-17T11:28:54Z","timestamp":1750159734803,"version":"3.37.3"},"reference-count":25,"publisher":"FapUNIFESP (SciELO)","issue":"suppl 2","license":[{"start":{"date-parts":[[2020,1,1]],"date-time":"2020-01-01T00:00:00Z","timestamp":1577836800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2020,1,1]],"date-time":"2020-01-01T00:00:00Z","timestamp":1577836800000},"content-version":"am","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2020,1,1]],"date-time":"2020-01-01T00:00:00Z","timestamp":1577836800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rev. Assoc. Med. Bras."],"abstract":"<jats:p>SUMMARY  OBJECTIVES  The 2019 Novel coronavirus disease puts a serious burden on the health system. Therefore, the detection of particularly serious patients at an early stage is extremely important in terms of controlling the outbreak and improving the prognosis. We investigated the role of inflammatory markers studied in patients suspected of COVID-19 at an emergency department in predicting PCR and CT results.  METHODS  This retrospective study was carried out with 133 patients who were admitted between 13 March and 1st April 2020 with suspicion of COVID-19. The patients were divided into four groups according to CT and RT-PCR results and evaluated.  RESULTS  Considering all patients, no specific findings were found in the hematological and biochemical values of patients in the laboratory analyses. Although all of the results remained within the reference range, there was a significant difference in white blood cell, neutrophil, platelet, and lymphocyte values when the groups were compared [p = 0.000; p = 0.004; p = 0.022; p = 0.023].  CONCLUSION  Laboratory is not specific enough in the pre-diagnosis. In addition, this result does not alter with PCR or CT positivity. However, minimal changes observed in laboratory results may be partially guiding in patients in whom both PCR and CT are positive.<\/jats:p>","DOI":"10.1590\/1806-9282.66.s2.58","type":"journal-article","created":{"date-parts":[[2020,9,21]],"date-time":"2020-09-21T19:36:47Z","timestamp":1600717007000},"page":"58-64","source":"Crossref","is-referenced-by-count":5,"title":["The diagnostic process of cov\u0131d-19 in the emergency department: laboratory and \u0131maging methods"],"prefix":"10.1590","volume":"66","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8433-3763","authenticated-orcid":false,"given":"Fatih","family":"Guneysu","sequence":"first","affiliation":[{"name":"Sakarya University,  Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3917-9434","authenticated-orcid":false,"given":"Yusuf","family":"Yurumez","sequence":"additional","affiliation":[{"name":"Sakarya University,  Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2860-2831","authenticated-orcid":false,"given":"Ertugrul","family":"Guclu","sequence":"additional","affiliation":[{"name":"Sakarya University,  Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8101-1104","authenticated-orcid":false,"given":"Mehmet","family":"Koroglu","sequence":"additional","affiliation":[{"name":"Sakarya University,  Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8930-9546","authenticated-orcid":false,"given":"Alper","family":"Karacan","sequence":"additional","affiliation":[{"name":"Sakarya University,  Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5052-9242","authenticated-orcid":false,"given":"Necip Gokhan","family":"Guner","sequence":"additional","affiliation":[{"name":"Sakarya University,  Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6577-7505","authenticated-orcid":false,"given":"Yesim","family":"Durgun","sequence":"additional","affiliation":[{"name":"Sakarya University,  Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"530","published-online":{"date-parts":[[2020]]},"reference":[{"issue":"8","key":"ref1","doi-asserted-by":"crossref","first-page":"727","DOI":"10.1056\/NEJMoa2001017","article-title":"A novel coronavirus from patients with pneumonia in China, 2019","volume":"382","author":"Zhu N","year":"2020","journal-title":"N Engl J Med"},{"year":"2020","series-title":"Coronavirus disease (COVID-2019) situation reports","key":"ref2"},{"issue":"18","key":"ref3","doi-asserted-by":"crossref","first-page":"1708","DOI":"10.1056\/NEJMoa2002032","article-title":"Clinical characteristics of coronavirus disease 2019 in China","volume":"382","author":"Guan W-J","year":"2020","journal-title":"N Engl J Med"},{"key":"ref4","doi-asserted-by":"crossref","DOI":"10.1016\/j.tmaid.2020.101623","article-title":"Clinical, laboratory and \u0131maging features of COVID-19: a systematic review and meta-analysis","volume":"34","author":"Rodriguez-Morales AJ","year":"2020","journal-title":"Travel Med Infect Dis"},{"issue":"11","key":"ref5","first-page":"e00169","article-title":"Complete genome sequence of a 2019 novel coronavirus (SARS-CoV-2) strain \u0131solated in Nepal","volume":"9","author":"Sah R","year":"2020","journal-title":"Microbiol Resour Announc"},{"key":"ref6","article-title":"Correlation of chest CT and RT-PCR testing in coronavirus disease 2019 (COVID-19) in China: a report of 1014 cases","author":"Ai T","year":"2020","journal-title":"Radiology"},{"issue":"1","key":"ref7","doi-asserted-by":"crossref","DOI":"10.1186\/s40249-020-00646-x","article-title":"Epidemiology, causes, clinical manifestation and diagnosis, prevention and control of coronavirus disease (COVID-19) during the early outbreak period: a scoping review","volume":"9","author":"Adhikari SP","year":"2020","journal-title":"Infect Dis Poverty"},{"issue":"4","key":"ref8","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1007\/s12098-020-03263-6","article-title":"A review of coronavirus disease-2019 (COVID-19)","volume":"87","author":"Singhal T","year":"2020","journal-title":"Indian J Pediatr"},{"issue":"1","key":"ref9","doi-asserted-by":"crossref","DOI":"10.1186\/s12931-020-01338-8","article-title":"Analysis of clinical characteristics and laboratory findings of 95 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a retrospective analysis","volume":"21","author":"Zhang G","year":"2020","journal-title":"Respir Res"},{"series-title":"COVID-19 Guide to Public Health in Turkey","key":"ref10"},{"issue":"3","key":"ref11","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1038\/d41573-020-00016-0","article-title":"Therapeutic options for the 2019 novel coronavirus (2019-nCoV)","volume":"19","author":"Li G","year":"2020","journal-title":"Nat Rev Drug Discov"},{"key":"ref12","article-title":"Characteristics of and \u0131mportant lessons from the coronavirus disease 2019 (COVID-19) outbreak in China: summary of a report of 72 314 cases from the Chinese Center for Disease Control and Prevention","author":"Wu Z","year":"2020","journal-title":"JAMA"},{"issue":"2","key":"ref13","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1515\/dx-2020-0046","article-title":"Clinical features, laboratory characteristics, and outcomes of patients hospitalized with coronavirus disease 2019 (COVID-19): early report from the United States","volume":"7","author":"Aggarwal S","year":"2020","journal-title":"Diagnosis (Berl)"},{"key":"ref14","doi-asserted-by":"crossref","DOI":"10.1016\/j.jcv.2020.104378","article-title":"Epidemiological characteristics of coronavirus disease 2019 (COVID-19) patients in Iran: a single center study","volume":"127","author":"Nikpouraghdam M","year":"2020","journal-title":"J Clin Virol"},{"issue":"10223","key":"ref15","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1016\/S0140-6736(20)30211-7","article-title":"Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study","volume":"395","author":"Chen N","year":"2020","journal-title":"Lancet"},{"issue":"3","key":"ref16","doi-asserted-by":"crossref","first-page":"308","DOI":"10.1007\/s12016-017-8648-x","article-title":"Sexual dimorphism in innate immunity","volume":"56","author":"Jaillon S","year":"2019","journal-title":"Clin Rev Allergy Immunol"},{"issue":"3","key":"ref17","doi-asserted-by":"crossref","first-page":"364","DOI":"10.1007\/s11427-020-1643-8","article-title":"Clinical and biochemical \u0131ndexes from 2019-nCoV \u0131nfected patients linked to viral loads and lung \u0131njury","volume":"63","author":"Liu Y","year":"2020","journal-title":"Sci China Life Sci"},{"issue":"4","key":"ref18","doi-asserted-by":"crossref","first-page":"1011","DOI":"10.1016\/S0016-5085(03)01215-0","article-title":"Enteric involvement of severe acute respiratory syndrome-associated coronavirus \u0131nfection","volume":"125","author":"Leung WK","year":"2003","journal-title":"Gastroenterology"},{"issue":"9371","key":"ref19","doi-asserted-by":"crossref","first-page":"1767","DOI":"10.1016\/S0140-6736(03)13412-5","article-title":"Clinical progression and viral load in a community outbreak of coronavirus-associated SARS pneumonia: a prospective study","volume":"361","author":"Peiris JSM","year":"2003","journal-title":"Lancet"},{"issue":"5","key":"ref20","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1056\/NEJMoa1306742","article-title":"Hospital outbreak of middle east respiratory syndrome coronavirus","volume":"369","author":"Assiri A","year":"2013","journal-title":"N Engl J Med"},{"issue":"5","key":"ref21","doi-asserted-by":"crossref","first-page":"140","DOI":"10.15585\/mmwr.mm6905e1","article-title":"Initial public health response and \u0131nterim clinical guidance for the 2019 novel coronavirus outbreak \u2014 United States, December 31, 2019\u2013February 4, 2020","volume":"69","author":"Patel A","year":"2020","journal-title":"MMWR Morb Mortal Wkly Rep"},{"issue":"6","key":"ref22","doi-asserted-by":"crossref","first-page":"3306","DOI":"10.1007\/s00330-020-06731-x","article-title":"Initial CT findings and temporal changes in patients with the novel coronavirus pneumonia (2019-Ncov): a study of 63 patients in Wuhan, China","volume":"30","author":"Pan Y","year":"2020","journal-title":"Eur Radiol"},{"issue":"6","key":"ref23","doi-asserted-by":"crossref","first-page":"701","DOI":"10.1016\/j.jacr.2020.03.006","article-title":"Coronavirus disease 2019 (COVID-19) CT findings: a systematic review and meta-analysis","volume":"17","author":"Bao C","year":"2020","journal-title":"J Am Coll Radiol"},{"issue":"13","key":"ref24","doi-asserted-by":"crossref","DOI":"10.2807\/1560-7917.ES.2020.25.13.2000280","article-title":"Only strict quarantine measures can curb the coronavirus disease (COVID-19) outbreak in Italy, 2020","volume":"25","author":"Sj\u00f6din H","year":"2020","journal-title":"Euro Surveill"},{"key":"ref25","article-title":"CT manifestations of coronavirus disease-2019: a retrospective analysis of 73 cases by disease severity","volume":"126","author":"Liu KC","year":"2020","journal-title":"Eur J Radiol"}],"container-title":["Revista da Associa\u00e7\u00e3o M\u00e9dica Brasileira"],"original-title":[],"link":[{"URL":"http:\/\/www.scielo.br\/pdf\/ramb\/v66s2\/1806-9282-ramb-66-s2-058.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,1,24]],"date-time":"2021-01-24T02:38:02Z","timestamp":1611455882000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.scielo.br\/scielo.php?script=sci_arttext&pid=S0104-42302020001400058&tlng=en"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020]]},"references-count":25,"journal-issue":{"issue":"suppl 2","published-online":{"date-parts":[[2020]]}},"alternative-id":["S0104-42302020001400058"],"URL":"https:\/\/doi.org\/10.1590\/1806-9282.66.s2.58","relation":{},"ISSN":["1806-9282","0104-4230"],"issn-type":[{"type":"electronic","value":"1806-9282"},{"type":"print","value":"0104-4230"}],"subject":[],"published":{"date-parts":[[2020]]}}}