{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,9]],"date-time":"2026-07-09T01:52:38Z","timestamp":1783561958636,"version":"3.55.0"},"reference-count":30,"publisher":"FapUNIFESP (SciELO)","license":[{"start":{"date-parts":[[2020,1,1]],"date-time":"2020-01-01T00:00:00Z","timestamp":1577836800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2020,1,1]],"date-time":"2020-01-01T00:00:00Z","timestamp":1577836800000},"content-version":"am","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2020,1,1]],"date-time":"2020-01-01T00:00:00Z","timestamp":1577836800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rev. bras. epidemiol."],"abstract":"<jats:p>RESUMO:  Introdu\u00e7\u00e3o:  Em 2014, o Brasil introduziu programa de imuniza\u00e7\u00e3o universal contra o v\u00edrus da hepatite A (HAV) para crian\u00e7as no segundo ano de vida, por meio de dose \u00fanica da vacina de v\u00edrus inativado. Este estudo teve como objetivo avaliar a cobertura vacinal (CV) contra o HAV no Brasil, diante da incid\u00eancia de casos notificados cinco anos ap\u00f3s a implanta\u00e7\u00e3o do programa.  Metodologia:  Dados secund\u00e1rios foram obtidos pesquisando-se s\u00edtios eletr\u00f4nicos de acesso livre do Minist\u00e9rio da Sa\u00fade, Departamento de Inform\u00e1tica do Sistema \u00danico de Sa\u00fade (DATASUS), para an\u00e1lise de incid\u00eancia e CV.  Resultados:  A CV variou entre 60,13 e 97,07%. A homogeneidade da CV contra hepatite A nos estados ficou aqu\u00e9m da meta estabelecida. Ap\u00f3s 2015, houve queda da CV em todas as regi\u00f5es do pa\u00eds. Apesar da cobertura insuficiente, houve redu\u00e7\u00e3o concomitante da incid\u00eancia da hepatite A em todo o Brasil. A taxa de incid\u00eancia caiu de 3,29 para 0,80\/100 mil entre 2014 e 2018. No entanto, ocorreu diminui\u00e7\u00e3o da velocidade de queda da incid\u00eancia entre 2017 e 2018, o que pode ser consequ\u00eancia dos percentuais insuficientes de CV. Esse fen\u00f4meno parece acompanhar tend\u00eancia geral de enfraquecimento do esfor\u00e7o vacinal no pa\u00eds, verificado tamb\u00e9m para outras vacinas, como poliomielite e tr\u00edplice viral.  Conclus\u00e3o:  Esses n\u00fameros sugerem a necessidade de esfor\u00e7os para melhorar as taxas de CV da hepatite A no pa\u00eds.<\/jats:p>","DOI":"10.1590\/1980-549720200073","type":"journal-article","created":{"date-parts":[[2020,7,7]],"date-time":"2020-07-07T01:47:22Z","timestamp":1594086442000},"source":"Crossref","is-referenced-by-count":22,"title":["Vacina\u00e7\u00e3o universal contra hepatite A no Brasil: an\u00e1lise da cobertura vacinal e da incid\u00eancia cinco anos ap\u00f3s a implanta\u00e7\u00e3o do programa"],"prefix":"10.1590","volume":"23","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0097-1520","authenticated-orcid":false,"given":"Wagner Izidoro de","family":"Brito","sequence":"first","affiliation":[{"name":"Universidade Federal de Mato Grosso,  Brazil; Empresa Brasileira de Servi\u00e7os Hospitalares,  Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2529-4119","authenticated-orcid":false,"given":"Francisco Jos\u00e9 Dutra","family":"Souto","sequence":"additional","affiliation":[{"name":"Universidade Federal de Mato Grosso,  Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"530","published-online":{"date-parts":[[2020]]},"reference":[{"issue":"3","key":"ref1","doi-asserted-by":"crossref","first-page":"600","DOI":"10.1093\/ije\/dyi062","article-title":"The effects of socioeconomic development on worldwide hepatitis A virus seroprevalence patterns","volume":"34","author":"Jacobsen KH","year":"2005","journal-title":"Int J Epidemiol"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"S71","DOI":"10.1016\/S0264-410X(99)00470-3","article-title":"Clinical course and consequences of hepatitis A infection","volume":"18","author":"Ciocca M","year":"2000","journal-title":"Vaccine"},{"issue":"2","key":"ref3","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1590\/S0074-02762006000200001","article-title":"Epidemiological pattern and mortality rates for hepatitis A in Brazil, 1980 - 2002: a review","volume":"101","author":"Vitral CL","year":"2006","journal-title":"Mem Inst Oswaldo Cruz"},{"key":"ref4","series-title":"Boletim epidemiol\u00f3gico: hepatites virais","year":"2011"},{"issue":"3","key":"ref5","doi-asserted-by":"crossref","first-page":"724","DOI":"10.1080\/21645515.2016.1242539","article-title":"Impact of universal mass vaccination with monovalent inactivated hepatitis A vaccines - A systematic review","volume":"13","author":"Stuurman AL","year":"2017","journal-title":"Hum Vaccin Immunother"},{"key":"ref6","series-title":"Informe t\u00e9cnico da introdu\u00e7\u00e3o da vacina adsorvida hepatite A (inativada)","year":"2014"},{"issue":"2","key":"ref7","doi-asserted-by":"crossref","first-page":"155","DOI":"10.5546\/aap.2013.155","article-title":"La introducci\u00f3n de la vacuna contra la hepatitis A en el Calendario Nacional de Vacunaci\u00f3n: unanuevarealidade: Hepatitis A immunisation in the argentinean mandatory schedule","volume":"111","author":"Gentile \u00c1","year":"2013","journal-title":"Arch Argent Pediatr"},{"key":"ref8","series-title":"Vacina\u00e7\u00e3o contra Hepatite A (Experi\u00eancia da Argentina)","author":"Parada L","year":"2015"},{"issue":"2","key":"ref9","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1016\/j.vaccine.2012.10.102","article-title":"WHO position paper on hepatitis A vaccine - June 2012-recommendations","volume":"31","year":"2013","journal-title":"Vaccine"},{"key":"ref10","series-title":"Nota informativa sobre mudan\u00e7as no calend\u00e1rio nacional de vacina\u00e7\u00e3o para o ano de 2017","year":"2017"},{"issue":"3","key":"ref11","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1016\/j.bjid.2018.04.001","article-title":"Initial evaluation of universal immunization with a single dose against hepatitis A virus in Central Brazil","volume":"22","author":"Brito WI","year":"2018","journal-title":"Braz J Infect Dis"},{"key":"ref12","series-title":"Indicadores b\u00e1sicos para a sa\u00fade no Brasil: conceitos e aplica\u00e7\u00f5es","year":"2008"},{"key":"ref13","series-title":"Coberturas vacinais no Brasil: Per\u00edodo: 2010-2014","year":"2015"},{"key":"ref14","series-title":"Sistema de Informa\u00e7\u00f5es do Programa Nacional de Imuniza\u00e7\u00e3o","year":"2019"},{"key":"ref15","series-title":"Queda nos \u00edndices das coberturas vacinais no Brasil","year":"2018"},{"key":"ref16","series-title":"Informa\u00e7\u00f5es de Sa\u00fade (TABNET). 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