{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T06:55:29Z","timestamp":1790492129891,"version":"4.1.0"},"reference-count":27,"publisher":"FapUNIFESP (SciELO)","license":[{"start":{"date-parts":[[2020,1,1]],"date-time":"2020-01-01T00:00:00Z","timestamp":1577836800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2020,1,1]],"date-time":"2020-01-01T00:00:00Z","timestamp":1577836800000},"content-version":"am","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2020,1,1]],"date-time":"2020-01-01T00:00:00Z","timestamp":1577836800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rev. bras. epidemiol."],"abstract":"<jats:p>ABSTRACT:  Introduction:  Poor oral hygiene, regular use of mouthwash and absence of visits to the dentist could correspond to potential risk factors for the development of head and neck cancer.  Objective: The objective of this study was to determine whether oral hygiene is associated with the occurrence of oral cavity and head and neck cancer in a Brazilian sample.  Method:  The variables of oral hygiene condition, such as toothbrushing frequency, dental loss, need and use of prosthesis, and regular visit to the dentist in a case-control study were analyzed in patients from five hospitals in the state of S\u00e3o Paulo, Brazil, paired by gender and age, from the multicenter project Genoma do C\u00e2ncer de Cabe\u00e7a e Pesco\u00e7o (GENCAPO).  Results:  The most frequent malignancies in the 899 patients included were those of the tongue border (11.41%) and tongue base (10.92%). The multivariable statistical analysis found odds ratio values: Brushing once 0.33 (95%CI 0.25 - 0.44); Brushing twice 0.42 (95%CI 0.35 - 0.52); Flossing always 0.19 (95%CI 0.13 - 0.27); Flossing sometimes 0.19 (95%CI 0.15 - 0.24); Bleeding 2.40 (95%CI 1.40 - 4.09); Prosthesis 1.99 (95%CI 1.54 - 2.56); Visiting the dentist 0.29 (95%CI 0.22 - 0.37); Good hygiene 0.21 (95%CI 0.17 - 0.27); Regular hygiene 0.20 (95%CI 0.15 - 0.25); number of missing teeth (6 or more) 3.30 (95%CI 2.67 - 4.08).  Conclusion:  These data showed that, in the population studied, indicators of good hygiene such as brushing teeth and flossing were protective factors for mouth and head and neck cancer, while bleeding and many missing teeth were risk factors.<\/jats:p>","DOI":"10.1590\/1980-549720200094","type":"journal-article","created":{"date-parts":[[2020,9,16]],"date-time":"2020-09-16T19:37:01Z","timestamp":1600285021000},"source":"Crossref","is-referenced-by-count":10,"title":["Association between oral hygiene and head and neck cancer in Brazil"],"prefix":"10.1590","volume":"23","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5400-5075","authenticated-orcid":false,"given":"Nayara Fernanda","family":"Pereira","sequence":"first","affiliation":[{"name":"Universidade de S\u00e3o Paulo,  Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7993-767X","authenticated-orcid":false,"given":"Rossana Mendoza","family":"L\u00f3pez","sequence":"additional","affiliation":[{"name":"Instituto do C\u00e2ncer do Estado de S\u00e3o Paulo,  Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8929-5137","authenticated-orcid":false,"given":"Tatiana Natasha","family":"Toporcov","sequence":"additional","affiliation":[{"name":"Universidade de S\u00e3o Paulo,  Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7903-1373","authenticated-orcid":false,"given":"Cl\u00e1udia Kliemann","family":"Schmerling","sequence":"additional","affiliation":[{"name":"Instituto de C\u00e2ncer Doutor Arnaldo,  Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2505-0461","authenticated-orcid":false,"given":"Rafael De","family":"Cicco","sequence":"additional","affiliation":[{"name":"Instituto de C\u00e2ncer Doutor Arnaldo,  Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8559-9769","authenticated-orcid":false,"given":"Edgard","family":"Michel-Crosato","sequence":"additional","affiliation":[{"name":"Universidade de S\u00e3o Paulo,  Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6326-5805","authenticated-orcid":false,"given":"Maria Gabriela Haye","family":"Biazevic","sequence":"additional","affiliation":[{"name":"Universidade de S\u00e3o Paulo,  Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"530","published-online":{"date-parts":[[2020]]},"reference":[{"issue":"10","key":"ref1","doi-asserted-by":"crossref","first-page":"769","DOI":"10.1111\/jop.12305","article-title":"Polymorphisms in alcohol and tobacco metabolism genes in head and neck cancer in the Basque Country","volume":"44","author":"Bediaga NG","year":"2015","journal-title":"J Oral Pathol 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