{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,12]],"date-time":"2026-05-12T02:48:44Z","timestamp":1778554124572,"version":"3.51.4"},"reference-count":42,"publisher":"FapUNIFESP (SciELO)","license":[{"start":{"date-parts":[[2022,1,1]],"date-time":"2022-01-01T00:00:00Z","timestamp":1640995200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2022,1,1]],"date-time":"2022-01-01T00:00:00Z","timestamp":1640995200000},"content-version":"am","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2022,1,1]],"date-time":"2022-01-01T00:00:00Z","timestamp":1640995200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rev. bras. epidemiol."],"abstract":"<jats:p>RESUMO:  Objetivo:  Analisar a tend\u00eancia temporal da cobertura vacinal de hepatite A, tr\u00edplice viral e varicela em um estado brasileiro no per\u00edodo de 2014 a 2020.  M\u00e9todos:  Estudo ecol\u00f3gico de s\u00e9ries temporais, que considerou dados dos 853 munic\u00edpios de Minas Gerais que comp\u00f5em as 14 regi\u00f5es do estado, sendo estas as unidades territoriais de an\u00e1lise. Foram analisados registros de doses aplicadas das vacinas hepatite A, tr\u00edplice viral e varicela registrados no Sistema de Informa\u00e7\u00e3o de Imuniza\u00e7\u00e3o do Brasil. As tend\u00eancias foram estimadas pela regress\u00e3o de Prais-Winsten e calculados os intervalos de confian\u00e7a 95% das medidas de varia\u00e7\u00e3o.  Resultados:  Identificaram-se baixas coberturas vacinais de hepatite A, tr\u00edplice viral e varicela. Coberturas acima de 95% foram observadas somente no ano de 2015 para a vacina contra hepatite A (98,8%) e, em 2016, para a varicela (98,4%). A vacina tr\u00edplice viral apresentou cobertura inferior a 95% em todos os anos analisados. Uma queda de 13,6 e 4,3% entre os anos de 2019 e 2020 foi identificada para as vacinas tr\u00edplice viral e hepatite A, respectivamente. Observou-se tend\u00eancia decrescente na cobertura vacinal da hepatite A nas regi\u00f5es Sul (p=0,041), Leste (p=0,030) e Norte (p=0,045); para a tr\u00edplice viral, nas regi\u00f5es Jequitinhonha (p=0,002), Leste (p=0,004) e Norte (p=0,024). A cobertura crescente foi observada somente para a varicela em oito regi\u00f5es do estado.  Conclus\u00f5es:  Os dados apontam heterogeneidade no comportamento temporal das coberturas vacinais em Minas Gerais. A tend\u00eancia decrescente em algumas regi\u00f5es desperta preocupa\u00e7\u00e3o pela possibilidade do recrudescimento de doen\u00e7as, como o sarampo, at\u00e9 ent\u00e3o controladas.<\/jats:p>","DOI":"10.1590\/1980-549720220010.2","type":"journal-article","created":{"date-parts":[[2022,5,9]],"date-time":"2022-05-09T08:25:25Z","timestamp":1652084725000},"source":"Crossref","is-referenced-by-count":7,"title":["Cobertura vacinal infantil de hepatite A, tr\u00edplice viral e varicela: an\u00e1lise de tend\u00eancia temporal em Minas Gerais, Brasil"],"prefix":"10.1590","volume":"25","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7009-4618","authenticated-orcid":false,"given":"Gabriela Cunha Corr\u00eaa Freitas de","family":"Oliveira","sequence":"first","affiliation":[{"name":"Universidade Federal de S\u00e3o Jo\u00e3o del Rei,  Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4772-4968","authenticated-orcid":false,"given":"Rayssa Nogueira","family":"Rodrigues","sequence":"additional","affiliation":[{"name":"Universidade Federal de Vi\u00e7osa,  Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2658-1363","authenticated-orcid":false,"given":"Marialice Caetano da","family":"Silva","sequence":"additional","affiliation":[{"name":"Universidade Federal de S\u00e3o Jo\u00e3o del Rei,  Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5647-4358","authenticated-orcid":false,"given":"Gabriela Louren\u00e7a Martins do","family":"Nascimento","sequence":"additional","affiliation":[{"name":"Universidade Federal de S\u00e3o Jo\u00e3o del Rei,  Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8250-180X","authenticated-orcid":false,"given":"Fernanda Moura","family":"Lanza","sequence":"additional","affiliation":[{"name":"Universidade Federal de S\u00e3o Jo\u00e3o del Rei,  Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5109-2687","authenticated-orcid":false,"given":"Josianne Dias","family":"Gusm\u00e3o","sequence":"additional","affiliation":[{"name":"Secretaria de Estado de Sa\u00fade de Minas Gerais,  Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2606-9754","authenticated-orcid":false,"given":"Val\u00e9ria Concei\u00e7\u00e3o de","family":"Oliveira","sequence":"additional","affiliation":[{"name":"Universidade Federal de S\u00e3o Jo\u00e3o del Rei,  Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9236-8643","authenticated-orcid":false,"given":"Eliete Albano de Azevedo","family":"Guimar\u00e3es","sequence":"additional","affiliation":[{"name":"Universidade Federal de S\u00e3o Jo\u00e3o del Rei,  Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"530","published-online":{"date-parts":[[2022]]},"reference":[{"issue":"42","key":"ref1","doi-asserted-by":"crossref","first-page":"937","DOI":"10.15585\/mmwr.mm6842a1","article-title":"Global routine vaccination coverage, 2018","volume":"68","author":"Peck M","year":"2019","journal-title":"MMWR Morb Mortal Wkly Rep"},{"issue":"4","key":"ref2","doi-asserted-by":"crossref","DOI":"10.1590\/0102-311x00015619","article-title":"\u00c1reas com queda da cobertura vacinal para BCG, poliomielite e tr\u00edplice viral no Brasil (2006-2016): mapas da heterogeneidade regional","volume":"36","author":"Arroyo LH","year":"2020","journal-title":"Cad Sa\u00fade P\u00fablica"},{"key":"ref3","doi-asserted-by":"crossref","DOI":"10.1590\/s1980-220x2020028303736","article-title":"Fake news sobre vacinas: uma ana\u0301lise sob o modelo dos 3Cs da Organizac\u0327a\u0303o Mundial da Sau\u0301de","volume":"55","author":"Frugoli AG","year":"2021","journal-title":"Rev Esc Enferm USP"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"40","DOI":"10.11606\/S1518-8787.2018052000384","article-title":"Eventos adversos de vacinas e as consequ\u00eancias da n\u00e3o vacina\u00e7\u00e3o: uma revis\u00e3o cr\u00edtica","volume":"52","author":"Aps LRMM","year":"2018","journal-title":"Rev Saude Publica"},{"issue":"3","key":"ref5","doi-asserted-by":"crossref","first-page":"988","DOI":"10.3390\/ijerph18030988","article-title":"The impact of the COVID-19 pandemic on immunization campaigns and programs: a systematic review","volume":"18","author":"Lassi ZS","year":"2021","journal-title":"Int J Environ Res Public Health"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1186\/s13690-020-00403-4","article-title":"Vaccine coverage within the first year of life and associated factors with incomplete immunization in a Brazilian birth cohort","volume":"78","author":"Buffarini R","year":"2020","journal-title":"Arch Public Health"},{"issue":"1","key":"ref7","article-title":"Acesso a\u0300 vacinac\u0327a\u0303o na Atenc\u0327a\u0303o Prima\u0301ria na voz do usua\u0301rio: sentidos e sentimentos frente ao atendimento","volume":"23","author":"Duarte DC","year":"2019","journal-title":"Esc Anna Nery"},{"key":"ref8","series-title":"Implementing the immunization agenda 2030: a framework for action through coordinated planning, monitoring & evaluation, ownership & accountability, and communications & advocacy","year":"2021"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"1526","DOI":"10.3389\/fmicb.2020.01526","article-title":"Impact of vaccines; health, economic and social perspectives","volume":"11","author":"Rodrigues CMC","year":"2020","journal-title":"Front Microbiol"},{"issue":"4","key":"ref10","first-page":"CD004407","article-title":"Vaccines for measles, mumps, rubella, and varicella in children","volume":"4","author":"Di Pietrantonj CD","year":"2020","journal-title":"Cochrane Database Syst Rev"},{"issue":"3","key":"ref11","first-page":"359","article-title":"The impact of varicella vaccination on varicella-related hospitalization rates: global data review","volume":"34","author":"Hirose M","year":"2016","journal-title":"Rev Paul Pediatr"},{"issue":"3","key":"ref12","doi-asserted-by":"crossref","DOI":"10.1542\/peds.2015-3741","article-title":"Global varicella vaccine effectiveness: a meta-analysis","volume":"137","author":"Marin M","year":"2016","journal-title":"Pediatrics"},{"issue":"2","key":"ref13","doi-asserted-by":"crossref","DOI":"10.33448\/rsd-v10i2.12026","article-title":"Varicela grave: an analysis of compulsory notifications, Brazil 2012 to 2019","volume":"10","author":"Manetti CL","year":"2021","journal-title":"RSD"},{"key":"ref14","series-title":"MMR Vaccine","author":"Bailey A","year":"2022"},{"key":"ref15","doi-asserted-by":"crossref","DOI":"10.1590\/1980-549720200073","article-title":"Vacina\u00e7\u00e3o universal contra hepatite A no Brasil: an\u00e1lise da cobertura vacinal e da incid\u00eancia cinco anos ap\u00f3s a implanta\u00e7\u00e3o do programa","volume":"23","author":"Brito WI","year":"2020","journal-title":"Rev Bras Epidemiol"},{"key":"ref16","series-title":"Hepatitis A","year":"2022"},{"key":"ref17","series-title":"Cidades e Estados","year":"2020"},{"key":"ref18","series-title":"Vacina mais Minas Gerais","year":"2022"},{"key":"ref19","series-title":"Coberturas vacinais no Brasil. Per\u00edodo: 2010-2014","year":"2015"},{"issue":"3","key":"ref20","doi-asserted-by":"crossref","first-page":"565","DOI":"10.5123\/S1679-49742015000300024","article-title":"Uso da an\u00e1lise de s\u00e9ries temporais em estudos epidemiol\u00f3gicos","volume":"24","author":"Antunes JLF","year":"2015","journal-title":"Epidemiol Serv Sa\u00fade"},{"issue":"2","key":"ref21","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1007\/s00431-018-3289-5","article-title":"Determinants of low measles vaccination coverage in children living in an endemic area","volume":"178","author":"Lo Vecchio A","year":"2019","journal-title":"Eur J Pediatr"},{"issue":"10","key":"ref22","doi-asserted-by":"crossref","first-page":"2348","DOI":"10.1080\/21645515.2018.1502528","article-title":"Vaccination coverage and associated factors among children aged 12 - 23 months in Northwest Ethiopia","volume":"14","author":"Tesfaye TD","year":"2018","journal-title":"Hum Vaccin Immunother"},{"key":"ref23","series-title":"Surto global de sarampo, uma amea\u00e7a crescente para crian\u00e7as","year":"2019"},{"key":"ref24","series-title":"Dados preliminares da OMS apontam que casos de sarampo em 2019 quase triplicaram em rela\u00e7\u00e3o ao ano passado","year":"2019"},{"key":"ref25","series-title":"Measles cases have tripled in Europe, fueled by Ukrainian outbreak. Science","author":"Wadman M","year":"2019"},{"issue":"19","key":"ref26","doi-asserted-by":"crossref","first-page":"2000848","DOI":"10.2807\/1560-7917.ES.2020.25.19.2000848","article-title":"Early impact of the coronavirus disease (COVID-19) pandemic and physical distancing measures on routine childhood vaccinations in England, January to April 2020","volume":"25","author":"McDonald HI","year":"2020","journal-title":"Euro Surveill"},{"issue":"41","key":"ref27","doi-asserted-by":"crossref","first-page":"913","DOI":"10.15585\/mmwr.mm6841e2","article-title":"Vaccination coverage by age 24 months among children born in 2015 and 2016 - National Immunization Survey-Child, United States, 2016-2018","volume":"68","author":"Hill HA","year":"2019","journal-title":"MMWR Morb Mortal Wkly Rep"},{"key":"ref28","series-title":"Sistema de Informac\u0327a\u0303o do Programa Nacional de Imunizac\u0327o\u0303es - SI-PNI","year":"2018"},{"issue":"3","key":"ref29","doi-asserted-by":"crossref","first-page":"9731","DOI":"10.34119\/bjhrv4n3-011","article-title":"A import\u00e2ncia da vacina\u00e7\u00e3o infantil para a erradica\u00e7\u00e3o do Sarampo","volume":"4","author":"Bonani LO","year":"2021","journal-title":"Brazilian Journal of Health Review"},{"issue":"10","key":"ref30","doi-asserted-by":"crossref","first-page":"e1264","DOI":"10.1016\/S2214-109X(20)30308-9","article-title":"Routine childhood immunization during the COVID-19 pandemic in Africa: a benefit-risk analysis of health benefits versus excess risk of SARS-CoV-2 infection","volume":"8","author":"Abbas K","year":"2020","journal-title":"Lancet Global Health"},{"key":"ref31","doi-asserted-by":"crossref","first-page":"96","DOI":"10.11606\/S1518-8787.2018052001199","article-title":"What is the importance of vaccine hesitancy in the drop of vaccination coverage in Brazil?","volume":"52","author":"Sato APS","year":"2018","journal-title":"Rev Saude Publica"},{"key":"ref32","doi-asserted-by":"crossref","first-page":"1","DOI":"10.53455\/re.v3i.29","article-title":"Cobertura vacinal da poliomielite na regi\u00e3o Nordeste do Brasil no primeiro ano de pandemia por Covid-19","volume":"3","author":"Santana E","year":"2022","journal-title":"Estrab\u00e3o"},{"key":"ref33","series-title":"Nota Informativa no 17-SEI\/2017-CGPNI\/DEVIT\/SVS\/MS. Informa acerca da situa\u00e7\u00e3o da distribui\u00e7\u00e3o de imunobiol\u00f3gicos na rotina do m\u00eas de julho\/2017","year":"2017"},{"key":"ref34","first-page":"20","article-title":"A queda da imuniza\u00e7\u00e3o no Brasil. Sa\u00fade em Foco","volume":"25","author":"Cruz A","year":"2017","journal-title":"Revista Consensus"},{"issue":"1","key":"ref35","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1186\/s12913-020-05175-9","article-title":"National Immunization Program Information System: implementation context assessment","volume":"20","author":"Silva BS","year":"2020","journal-title":"BMC Health Serv Res"},{"key":"ref36","series-title":"e-SUS Aten\u00e7\u00e3o b\u00e1sica: manual do sistema com prontu\u00e1rio eletr\u00f4nico do cidad\u00e3o PEC - Vers\u00e3o 3.2","year":"2020"},{"issue":"10","key":"ref37","doi-asserted-by":"crossref","first-page":"1900","DOI":"10.3390\/v13101900","article-title":"Hepatitis A: epidemiology, high-risk groups, prevention and research on antiviral treatment","volume":"13","author":"Migueres M","year":"2021","journal-title":"Viruses"},{"issue":"8","key":"ref38","doi-asserted-by":"crossref","first-page":"1879","DOI":"10.1080\/21645515.2017.1330733","article-title":"The effectiveness of measles-mumps-rubella (MMR) vaccination in the prevention of pediatric hospitalizations for targeted and untargeted infections: a retrospective cohort study","volume":"13","author":"La Torre G","year":"2017","journal-title":"Hum Vaccin Immunother"},{"key":"ref39","series-title":"Plano Mineiro de Desenvolvimento Integrado 2016 a 2027. Perfis Territoriais","year":"2015"},{"issue":"6","key":"ref40","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pmed.1002578","article-title":"The state of the antivaccine movement in the United States: a focused examination of nonmedical exemptions in states and counties","volume":"15","author":"Olive JK","year":"2018","journal-title":"PLoS Med"},{"key":"ref41","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1186\/1472-6963-8-134","article-title":"Too little but not too late: results of a literature review to improve routine immunization programs in developing countries","volume":"8","author":"Ryman TK","year":"2008","journal-title":"BMC Health Services Research"},{"issue":"2","key":"ref42","doi-asserted-by":"crossref","first-page":"1800663","DOI":"10.2807\/1560-7917.ES.2019.24.2.1800663","article-title":"Measles outbreak: preliminary report on a case series of the first 8,070 suspected cases, Manaus, Amazonas state, Brazil, February to November 2018","volume":"24","author":"Elidio GA","year":"2019","journal-title":"Euro Surveill"}],"container-title":["Revista Brasileira de Epidemiologia"],"original-title":["Childhood vaccination coverage of hepatitis A, measles, mumps and rubella, and varicella: temporal trend analysis in Minas Gerais, Brazil"],"link":[{"URL":"http:\/\/www.scielo.br\/scielo.php?script=sci_pdf&pid=S1415-790X2022000100407&tlng=pt","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,5,9]],"date-time":"2022-05-09T08:26:03Z","timestamp":1652084763000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.scielo.br\/scielo.php?script=sci_arttext&pid=S1415-790X2022000100407&tlng=pt"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022]]},"references-count":42,"alternative-id":["S1415-790X2022000100407"],"URL":"https:\/\/doi.org\/10.1590\/1980-549720220010.2","relation":{"is-translation-of":[{"id-type":"doi","id":"10.1590\/1980-549720220010","asserted-by":"subject"},{"id-type":"doi","id":"10.1590\/1980-549720220010","asserted-by":"object"}]},"ISSN":["1980-5497","1415-790X"],"issn-type":[{"value":"1980-5497","type":"electronic"},{"value":"1415-790X","type":"print"}],"subject":[],"published":{"date-parts":[[2022]]},"article-number":"e220010"}}