{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T19:28:18Z","timestamp":1790882898845,"version":"4.1.0"},"reference-count":31,"publisher":"FapUNIFESP (SciELO)","license":[{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"am","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rev. bras. epidemiol."],"abstract":"<jats:p>ABSTRACT  Objective: To analyze the spatiotemporal epidemiological dynamics of meningitis in Brazil, between 2010 and 2019.  Methods: Descriptive ecological study with cases and deaths due to meningitis in Brazil (2010-2019) in the National Notifiable Diseases Information System (Sistema de Informa\u00e7\u00f5es de Agravos de Notifica\u00e7\u00e3o \u2013 SINAN). The following analyses were performed: (I) frequency analyses of cases and deaths, prevalence rates, mortality, lethality, Fisher's exact test, and chi-square test; (II) Prais-Winstein regression; and (III) Global, Local Moran's index, and Kernel density.  Results: 182,126 cases of meningitis were reported in Brazil, of which 16,866 (9.26%) resulted in death, with prevalence rates of 9.03\/100,000 inhabitants, mortality of 0.84\/100,000 inhabitants, and lethality of 9.26%. There was a noted trend of decreasing prevalence rates (\u22129.5%, 95% confidence interval \u2014 95%CI \u221213.92; \u22124.96, p&lt;0.01) and mortality (\u221211.74%, 95%CI \u221213.92; \u22129.48, p&lt;0.01), while lethality remained stable (\u22122.08%, 95%CI \u22124.9; 0.8; p&lt;0.1941). The majority of cases were viral meningitis (45.7%), among 1-9 years old (32.2%), while the highest proportion of deaths was due to bacterial meningitis (68%), among 40-59 years old (26.3%). In the Moran and Kernel maps of prevalence and mortality rates, municipalities in the South, Southeast, and the capital of Pernambuco in the Northeast stood out with high rates; as for lethality, the North, Northeast, and Southeast coastal areas were highlighted.  Conclusion: A decrease in meningitis cases and deaths was found in this study; however, the lethality rate was higher in areas with lower prevalence, emphasizing the need to enhance actions for identifying, monitoring, and providing health care for cases, as well as expanding vaccination coverage.<\/jats:p>","DOI":"10.1590\/1980-549720240031","type":"journal-article","created":{"date-parts":[[2024,6,14]],"date-time":"2024-06-14T08:37:54Z","timestamp":1718354274000},"source":"Crossref","is-referenced-by-count":7,"title":["Geography and public health: analysis of the epidemiological dynamics of meningitis in Brazil, between 2010 and 2019"],"prefix":"10.1590","volume":"27","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6194-7615","authenticated-orcid":false,"given":"Luis Roberto da","family":"Silva","sequence":"first","affiliation":[{"name":"School of Medicine of Universidade de S\u00e3o Paulo,  Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5023-5460","authenticated-orcid":false,"given":"La\u00eds Eduarda Silva de","family":"Arruda","sequence":"additional","affiliation":[{"name":"Funda\u00e7\u00e3o Oswaldo Cruz, Instituto Aggeu Magalh\u00e3es,  Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7965-0860","authenticated-orcid":false,"given":"Isabel de Jesus Brand\u00e3o","family":"Barreto","sequence":"additional","affiliation":[{"name":"Universidade Federal de Pernambuco, Academic Center of Vit\u00f3ria,  Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9219-5081","authenticated-orcid":false,"given":"Jo\u00e3o Victor Rodrigues de","family":"Arag\u00e3o","sequence":"additional","affiliation":[{"name":"Centro Universit\u00e1rio Uninovafapi,  Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3131-6166","authenticated-orcid":false,"given":"Maria Luiza Ferreira Imburana da","family":"Silva","sequence":"additional","affiliation":[{"name":"Recife Health Secretariat, Multiprofessional Residency Program in Health Surveillance,  Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5433-946X","authenticated-orcid":false,"given":"Guilherme","family":"Lira","sequence":"additional","affiliation":[{"name":"Universidade Federal de Pernambuco,  Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5630-4180","authenticated-orcid":false,"given":"Camila Maria Barros","family":"Teixeira","sequence":"additional","affiliation":[{"name":"Universidade Federal de Pernambuco,  Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0957-1542","authenticated-orcid":false,"given":"Em\u00edlia Carolle Azevedo de","family":"Oliveira","sequence":"additional","affiliation":[{"name":"Funda\u00e7\u00e3o Oswaldo Cruz,  Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"530","published-online":{"date-parts":[[2024]]},"reference":[{"issue":"10","key":"ref1","article-title":"Aspectos epidemiol\u00f3gicos das meningites virais no estado do Piau\u00ed no per\u00edodo de 2007 a 2017","volume":"11","author":"Gomes LS","year":"2019","journal-title":"Rev Eletr\u00f4nica Acervo Sa\u00fade"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"16074","DOI":"10.1038\/nrdp.2016.74","article-title":"Community-acquired bacterial meningitis","volume":"2","author":"van de Beek D","year":"2016","journal-title":"Nat Rev Dis Primers"},{"issue":"1","key":"ref3","first-page":"34","article-title":"Meningite no Brasil 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do Tocantins"},{"issue":"2","key":"ref7","first-page":"1061","article-title":"Global, regional, and national burden of meningitis, 1990\u20132016: a systematic analysis for the Global Burden of Disease Study 2016","volume":"17","year":"2018","journal-title":"Lancet Neurol"},{"key":"ref8","series-title":"Minist\u00e9rio da Sa\u00fade. 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