{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T11:25:23Z","timestamp":1786965923968,"version":"build-2736575974"},"reference-count":30,"publisher":"FapUNIFESP (SciELO)","license":[{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"am","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rev. bras. epidemiol."],"abstract":"<jats:p>ABSTRACT  Objective: The study aimed to analyze the trends in mortality and disease burden due to Diabetes Mellitus in Argentina from 1990 to 2022.  Methods: A longitudinal descriptive time-series study was conducted. Age-standardized mortality rates (ASMRs) and age-adjusted potential years of life lost (AAYPLL) were calculated. Trend analysis was performed using segmented regression (Joinpoint).  Results: Between 1990 and 2022, a total of 270,394 deaths from diabetes mellitus were recorded in Argentina, of which 52.1% occurred among men and 48.8% among women. ASMRs and AAYPLL analyses consistently showed higher values among men than among women. The average annual percent change (AAPC) for both ASMRs and AAYPLL indicated a plateau among men and a significant decrease among women.  Conclusion: The findings suggest a slight trend toward a decrease in the age at death among men, whereas the opposite pattern was observed among women. These findings have important implications for public health and policymaking. The high number of DM-related deaths among older age groups underscores the need for healthcare services tailored to the aging population. Furthermore, gender differences in mortality, with women tending to die at older ages than men, suggest that healthcare strategies should address gender-specific needs and risks.<\/jats:p>","DOI":"10.1590\/1980-549720260039","type":"journal-article","created":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T10:44:46Z","timestamp":1786963486000},"source":"Crossref","is-referenced-by-count":0,"title":["Trends in mortality and disease burden from diabetes mellitus in Argentina between 1990 and 2022"],"prefix":"10.1590","volume":"29","author":[{"ORCID":"https:\/\/orcid.org\/0009-0000-7522-7259","authenticated-orcid":false,"given":"Camila Soledad","family":"Dominguez","sequence":"first","affiliation":[{"name":"Funda\u00e7\u00e3o Oswaldo Cruz,  Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0880-9608","authenticated-orcid":false,"given":"Guillermo Ra\u00fal","family":"Macias","sequence":"additional","affiliation":[{"name":"Universidad Nacional de La Matanza,  Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"530","published-online":{"date-parts":[[2026]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"109049","DOI":"10.1016\/j.diabres.2021.109049","article-title":"IDF Diabetes Atlas: the prevalence of pre-existing diabetes in pregnancy \u2013 a systematic review and meta-analysis of studies published during 2010\u20132020","volume":"183","author":"Chivese T","year":"2022","journal-title":"Diabetes Res Clin Pract"},{"key":"ref2","series-title":"La OMS revela las principales causas de muerte y discapacidad en el mundo: 2000-2019 [Internet]","year":"2020"},{"key":"ref3","series-title":"Carga de enfermedad por diabetes [Internet]","year":"2021"},{"issue":"10397","key":"ref4","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1016\/S0140-6736(23)01301-6","article-title":"Global, regional, and national burden of diabetes from 1990 to 2021, with projections of prevalence to 2050: a systematic analysis for the Global Burden of Disease Study 2021","volume":"402","author":"Ong KL","year":"2023","journal-title":"Lancet"},{"issue":"9","key":"ref5","doi-asserted-by":"crossref","first-page":"655","DOI":"10.1016\/S2213-8587(22)00186-3","article-title":"Burden of diabetes and hyperglycaemia in adults in the Americas, 1990\u20132019: a systematic analysis for the Global Burden of Disease Study 2019","volume":"10","year":"2022","journal-title":"Lancet Diabetes Endocrinol"},{"issue":"3","key":"ref6","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1016\/j.gaceta.2015.01.015","article-title":"Carga de la mortalidad por diabetes mellitus en Am\u00e9rica Latina 2000-2011: los casos de Argentina, Chile, Colombia y M\u00e9xico","volume":"29","author":"Agudelo-Botero M","year":"2015","journal-title":"Gac Sanitaria"},{"key":"ref7","doi-asserted-by":"crossref","DOI":"10.26633\/RPSP.2017.73","article-title":"An\u00e1lisis de la tendencia temporal de la mortalidad por diabetes mellitus en Argentina, 1990-2013","volume":"41","author":"Hern\u00e1ndez H","year":"2017","journal-title":"Rev Panam Salud Publica"},{"issue":"3","key":"ref8","first-page":"185","article-title":"Tendencias de la mortalidad por diabetes mellitus en Chile (1990\u20132020)","volume":"34","author":"Vargas Contreras B","year":"2023","journal-title":"Revista M\u00e9dica Cl\u00ednica Las Condes"},{"key":"ref9","article-title":"Evoluci\u00f3n de la mortalidad y carga por diabetes mellitus en Cuba, 1987-2016","author":"Jim\u00e9nez DP","year":"2022","journal-title":"IV Convenci\u00f3n Internacional de Salud 17-21 de octubre"},{"issue":"2","key":"ref10","first-page":"2","article-title":"Tendencias y an\u00e1lisis espacio-temporal de la mortalidad por diabetes mellitus en Ecuador, 2001-2016","volume":"46","author":"N\u00fa\u00f1ez-Gonz\u00e1lez S","year":"2020","journal-title":"Rev Cubana Salud P\u00fablica"},{"key":"ref11","series-title":"4\u00b0 Encuesta Nacional de Factores de Riesgo. Resultados definitivos [Internet]","year":"2019"},{"key":"ref12","series-title":"International classification of diseases: ninth revision, basic tabulation list with alphabetic index","year":"1978"},{"key":"ref13","series-title":"Clasificaci\u00f3n estad\u00edstica internacional de enfermedades y problemas relacionados con la salud","year":"2002"},{"issue":"2","key":"ref14","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1590\/S1135-57272006000200005","article-title":"Correspondencias entre CIE-10 y CIE-9 para las listas de causas de muerte del Instituto Nacional de Estad\u00edstica y de la Regi\u00f3n de Murcia","volume":"80","author":"Cirera Su\u00e1rez L","year":"2006","journal-title":"Rev Esp Salud P\u00fablica"},{"issue":"2","key":"ref15","article-title":"Cambios en la esperanza de vida de Argentina 2019-2022","volume":"34","author":"Gonz\u00e1lez LM","year":"2025","journal-title":"Saude Soc"},{"key":"ref16","series-title":"Censos [Internet]","year":"2022"},{"key":"ref17","series-title":"Technical Briefing 3: commonly used public health statistics and their confidence intervals [Internet]","author":"Eayres D","year":"2008"},{"key":"ref18","article-title":"Direcci\u00f3n de Estad\u00edsticas e Informaci\u00f3n de Salud. Evoluci\u00f3n de la mortalidad seg\u00fan causas","year":"2008","journal-title":"Rep\u00fablica Argentina \u2013 Per\u00edodo 1997\u20132006 [Internet]"},{"key":"ref19","series-title":"Direcci\u00f3n de Estad\u00edsticas e Informaci\u00f3n en Salud. 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Argentina, 1980 2001","author":"Loria D","year":"2007"},{"key":"ref24","series-title":"EPIDAT Versi\u00f3n 4.2 [Internet]","year":"2016"},{"key":"ref25","article-title":"Division of Cancer Control & Population Sciences","journal-title":"Joinpoint trend analysis software [Internet]"},{"key":"ref26","series-title":"Perfiles carga enfermedad diabetes 2023 [Internet]","year":"2023"},{"issue":"1","key":"ref27","doi-asserted-by":"crossref","first-page":"1","DOI":"10.32811\/25954482-2019v2n1p57","article-title":"Tend\u00eancia da mortalidade por Diabetes Mellitus no Paran\u00e1, Brasil, entre 1984 e 2014","volume":"2","author":"Pinto MS","year":"2019","journal-title":"Revista de Sa\u00fade P\u00fablica do Paran\u00e1"},{"issue":"17","key":"ref28","first-page":"39","article-title":"El tratamiento de la diabetes mellitus en la normativa sanitaria argentina: una sistematizaci\u00f3n","volume":"4","author":"Lawrynowicz A","year":"2013","journal-title":"Rev Argent Salud P\u00fablica"},{"issue":"3","key":"ref29","doi-asserted-by":"crossref","first-page":"86","DOI":"10.18004\/mem.iics\/1812-9528\/2016.014(03)86-095","article-title":"Causas de defunci\u00f3n mal definidas en las provincias de Argentina, 2001-2013","volume":"14","author":"Ribotta BS","year":"2016","journal-title":"Mem Inst Invest Cienc Salud"},{"issue":"17","key":"ref30","doi-asserted-by":"crossref","first-page":"153","DOI":"10.4067\/S0718-65682018000100153","article-title":"Diferencias de g\u00e9nero en salud y calidad de vida en personas mayores del norte de Chile","author":"Gallardo-Peralta L","year":"2018","journal-title":"Polis"}],"container-title":["Revista Brasileira de Epidemiologia"],"original-title":["Tendencia de la mortalidad y carga de enfermedad por diabetes mellitus en Argentina entre 1990\u20132022"],"link":[{"URL":"http:\/\/www.scielo.br\/scielo.php?script=sci_pdf&pid=S1415-790X2026000101036&tlng=en","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T10:44:49Z","timestamp":1786963489000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.scielo.br\/scielo.php?script=sci_arttext&pid=S1415-790X2026000101036&tlng=en"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026]]},"references-count":30,"alternative-id":["S1415-790X2026000101036"],"URL":"https:\/\/doi.org\/10.1590\/1980-549720260039","relation":{"is-translation-of":[{"id-type":"doi","id":"10.1590\/1980-549720260039.2","asserted-by":"subject"},{"id-type":"doi","id":"10.1590\/1980-549720260039.2","asserted-by":"object"}]},"ISSN":["1980-5497","1415-790X"],"issn-type":[{"value":"1980-5497","type":"electronic"},{"value":"1415-790X","type":"print"}],"subject":[],"published":{"date-parts":[[2026]]},"article-number":"e260039"}}