{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,4,22]],"date-time":"2024-04-22T09:18:30Z","timestamp":1713777510991},"reference-count":30,"publisher":"FapUNIFESP (SciELO)","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["CoDAS"],"abstract":"<jats:p>RESUMO  Introdu\u00e7\u00e3o Poucos estudos realizaram, concomitantemente, o potencial evocado auditivo de tronco encef\u00e1lico (PEATE) e o P300 na S\u00edndrome de Down (SD), em indiv\u00edduos audiologicamente normais, para a avalia\u00e7\u00e3o da via auditiva central, principalmente pela dificuldade de realizar estes procedimentos nesta popula\u00e7\u00e3o. Estudos anteriores sugeriram que indiv\u00edduos com SD podem apresentar padr\u00f5es de respostas diferentes das encontradas em indiv\u00edduos com desenvolvimento t\u00edpico, sendo que a identifica\u00e7\u00e3o destes seria fundamental para o estabelecimento de um diagn\u00f3stico audiol\u00f3gico preciso.  Objetivo Caracterizar o PEATE e o P300 em indiv\u00edduos com SD audiologicamente normais.  M\u00e9todo Foram analisados o PEATE e o P300 de 17 indiv\u00edduos com SD e 21 com desenvolvimento t\u00edpico de sete a 15 anos. A an\u00e1lise foi quantitativa e qualitativa, utilizando medidas descritivas e os testes de hip\u00f3tese.  Resultados Os valores de lat\u00eancia foram menores no PEATE para o grupo SD, com diferen\u00e7a estatisticamente significante para a onda V, interpicos III-V e I-V; n\u00e3o foram encontradas diferen\u00e7as significantes nos valores de lat\u00eancia do P300. Observou-se maior n\u00famero de indiv\u00edduos com valores precoces para as lat\u00eancias do PEATE e com lat\u00eancias atrasadas para o P300 no grupo SD; ambas as compara\u00e7\u00f5es mostraram diferen\u00e7as significantes.  Conclus\u00e3o Crian\u00e7as e adolescentes com SD podem apresentar respostas precoces para os componentes do PEATE, sugerindo que a via auditiva destes necessita de menor tempo para a transmiss\u00e3o neural do est\u00edmulo ac\u00fastico at\u00e9 o tronco encef\u00e1lico. Quanto ao P300, indiv\u00edduos com SD podem apresentar lat\u00eancias aumentadas, sugerindo comprometimento na via auditiva central quanto ao processamento cortical da informa\u00e7\u00e3o auditiva.<\/jats:p>","DOI":"10.1590\/2317-1782\/20162015266","type":"journal-article","created":{"date-parts":[[2016,12,11]],"date-time":"2016-12-11T01:01:31Z","timestamp":1481418091000},"page":"717-723","source":"Crossref","is-referenced-by-count":6,"title":["Caracteriza\u00e7\u00e3o eletrofisiol\u00f3gica da audi\u00e7\u00e3o em indiv\u00edduos com S\u00edndrome de Down"],"prefix":"10.1590","volume":"28","author":[{"given":"Hellen Medeiros","family":"Kazan","sequence":"first","affiliation":[{"name":"Universidade de S\u00e3o Paulo,  Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alessandra Giannella","family":"Samelli","sequence":"additional","affiliation":[{"name":"Universidade de S\u00e3o Paulo,  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