{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T15:16:09Z","timestamp":1753888569296,"version":"3.41.2"},"reference-count":25,"publisher":"FapUNIFESP (SciELO)","issue":"5","license":[{"start":{"date-parts":[[2020,1,1]],"date-time":"2020-01-01T00:00:00Z","timestamp":1577836800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2020,1,1]],"date-time":"2020-01-01T00:00:00Z","timestamp":1577836800000},"content-version":"am","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2020,1,1]],"date-time":"2020-01-01T00:00:00Z","timestamp":1577836800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["CoDAS"],"abstract":"<jats:p>RESUMO  Objetivo: Verificar a associa\u00e7\u00e3o entre Refluxo laringofar\u00edngeo (RLF) com idade, sexo, desvio vocal e queixas de voz.  M\u00e9todo: Participaram do estudo pacientes entre 18 e 70 anos, encaminhados ao servi\u00e7o de otorrinolaringologia por queixas de voz ou refluxo, de ambos os sexos. Os achados endolar\u00edngeos foram classificados utilizando a escala Reflux Finding Score (RFS). A presen\u00e7a ou n\u00e3o de queixas vocais e de refluxo foi verificada e correlacionada com a classifica\u00e7\u00e3o RFS. Na mesma data, os pacientes foram submetidos \u00e0 grava\u00e7\u00e3o de voz de vogal sustentada e fala encadeada. A avalia\u00e7\u00e3o perceptivo-auditiva foi realizada por uma fonoaudi\u00f3loga, classificando o grau geral do desvio vocal com base na escala GRBASI.  Resultados: Foram avaliados 97 pacientes, com m\u00e9dia de idade de 42,6 anos, sendo 62,3% do sexo feminino e m\u00e9dia dos escores da escala RFS igual a 6,26 pontos. Do total de pacientes, 48 indiv\u00edduos apresentavam queixas vocais, sendo 34 mulheres com idade m\u00e9dia de 44,9 anos e escore RFS m\u00e9dio de 6,94 pontos. Os outros 49 indiv\u00edduos n\u00e3o apresentavam queixas vocais, e desses 27 eram mulheres, com idade m\u00e9dia de 41,2 anos e m\u00e9dia de escore RFS igual a 5,5 pontos. As vari\u00e1veis \u201cqueixa de refluxo\u201d, \u201cqueixa vocal\u201d e idade foram as que mais se correlacionaram com os escores da escala RFS.  Conclus\u00e3o: H\u00e1 rela\u00e7\u00e3o entre queixas de refluxo, achados lar\u00edngeos e queixa vocal.<\/jats:p>","DOI":"10.1590\/2317-1782\/20202018052","type":"journal-article","created":{"date-parts":[[2020,11,9]],"date-time":"2020-11-09T19:39:13Z","timestamp":1604950753000},"source":"Crossref","is-referenced-by-count":6,"title":["Sinais e sintomas de refluxo laringofar\u00edngeo e sua rela\u00e7\u00e3o com queixas e qualidade vocal"],"prefix":"10.1590","volume":"32","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8704-5380","authenticated-orcid":false,"given":"Gabriela","family":"Ricci","sequence":"first","affiliation":[{"name":"Centro de Estudos da Voz,  Brasil; Universidade de S\u00e3o Paulo,  Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5006-8482","authenticated-orcid":false,"given":"Aline Epiphanio","family":"Wolf","sequence":"additional","affiliation":[{"name":"Universidade de S\u00e3o Paulo,  Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8959-2211","authenticated-orcid":false,"given":"Aline Pires","family":"Barbosa","sequence":"additional","affiliation":[{"name":"Universidade de S\u00e3o Paulo,  Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8482-9702","authenticated-orcid":false,"given":"Felipe","family":"Moreti","sequence":"additional","affiliation":[{"name":"Centro de Estudos da Voz,  Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2280-5972","authenticated-orcid":false,"given":"Ingrid","family":"Gielow","sequence":"additional","affiliation":[{"name":"Centro de Estudos da Voz,  Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4663-4546","authenticated-orcid":false,"given":"Mara","family":"Behlau","sequence":"additional","affiliation":[{"name":"Centro de Estudos da Voz,  Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"530","published-online":{"date-parts":[[2020]]},"reference":[{"key":"ref1","series-title":"Voz - O Livro do Especialista","volume-title":"Conceito de Voz Normal e Classifica\u00e7\u00e3o das Disfonias","author":"Behlau M","year":"2001"},{"issue":"3","key":"ref2","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1016\/S0892-1997(96)80001-4","article-title":"Laryngopharyngeal reflux: consensus conference report","volume":"10","author":"Koufman J","year":"1996","journal-title":"J Voice"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1053\/S1542-3565(03)00177-0","article-title":"Laryngeal signs and symptoms and gastroesophageal reflux disease (GERD): a critical assessment of cause and effect association","volume":"1","author":"Vaezi MF","year":"2003","journal-title":"Clin Gastroenterol Hepatol"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"564","DOI":"10.1016\/S0892-1997(02)00132-7","article-title":"The prevalence of hypopharynx findings associated with gastroesophageal reflux in normal volunteers","volume":"16","author":"Hicks DM","year":"2002","journal-title":"J Voice"},{"issue":"2","key":"ref5","doi-asserted-by":"crossref","first-page":"280","DOI":"10.1016\/j.jvoice.2018.11.002","article-title":"Vocal Tract Discomfort and Dysphonia in Patients Undergoing Empiric Therapeutic Trial with Proton Pump Inhibitor for Suspected Laryngopharyngeal Reflux","volume":"34","author":"Mozzanica M","year":"2020","journal-title":"J Voice"},{"issue":"1","key":"ref6","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1097\/SLA.0000000000001907","article-title":"Diagnosis and Treatment of the Extraesophageal Manifestations of Gastroesophageal Reflux Disease","volume":"265","author":"Sidhwa F","year":"2017","journal-title":"Ann Surg"},{"issue":"2","key":"ref7","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1590\/S0004-28032005000200011","article-title":"Prevalence of heartburn and gastroesophageal reflux disease in the urban Brazilian population","volume":"42","author":"Moraes-Filho JP","year":"2005","journal-title":"Arq Gastroenterol"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"486","DOI":"10.1016\/j.jvoice.2013.03.001","article-title":"Reflux Laryngitis: an update, 2009-2012","volume":"4","author":"Hawkshaw MJ","year":"2013","journal-title":"J Voice"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1053\/S1542-3565(03)00177-0","article-title":"Laryngeal signs and symptoms and gastroesophageal reflux disease (GERD): a critical assessment of cause and effect association","volume":"1","author":"Vaezi MF","year":"2003","journal-title":"Clin Gastroenterol Hepatol"},{"issue":"53","key":"ref10","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1002\/lary.1991.101.s53.1","article-title":"The otolaryngologic manifestations of gastroesophageal reflux disease (GERD): A clinical investigation of 225 patients using ambulatory 24-hour pH monitoring and an experimental investigation of the role of acid and pepsin in the development of laryngeal injury","volume":"101","author":"Koufman JA","year":"1991","journal-title":"Laryngoscope"},{"issue":"4","key":"ref11","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1067\/mhn.2000.109935","article-title":"Prevalence of reflux in 113 consecutive patients with laryngeal and voice disorders","volume":"123","author":"Koufman JA","year":"2000","journal-title":"Otolaryngol Head Neck Surg"},{"key":"ref12","article-title":"Refluxo laringofar\u00edngeo: declara\u00e7\u00e3o de posi\u00e7\u00e3o do comit\u00ea sobre transtornos de fala, voz e degluti\u00e7\u00e3o da Academia Americana de Otorrinolaringologia - Cirurgia de Cabe\u00e7a e Pesco\u00e7o","volume":"127-132","author":"Koufman JA","year":"2002","journal-title":"Otolaryngol Head Neck Surg"},{"key":"ref13","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1177\/0194599811422014","article-title":"Combination of voice therapy and antireflux therapy rapidly recovers voice-related symptoms in laryngopharyngeal reflux patients","volume":"146","author":"Park JO","year":"2012","journal-title":"Otolaryngol Head Neck Surg"},{"issue":"4","key":"ref14","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1067\/mhn.2000.109935","article-title":"Prevalence of reflux in 113 consecutive patients with laryngeal and voice disorders. Otolaryngol","volume":"123","author":"Koufman JA Amin MR","year":"2000","journal-title":"Head Neck Surg"},{"issue":"1","key":"ref15","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1590\/S0004-28032007000100009","article-title":"Preval\u00eancia de queixas supra-esof\u00e1gicas em pacientes com doen\u00e7as do refluxo erosiva e n\u00e3o-erosiva","volume":"44","author":"Aguero GC","year":"2007","journal-title":"Arq Gastroenterol"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1002\/lary.1991.101.s53.1","article-title":"The otolaryngologic manifestations of gastroesophageal reflux disease (GERD): a clinical investigation of 225 patients using ambulatory 24-hour pH monitoring and an experimental investigation of the role of acid and pepsin in the development of laryngeal injury","volume":"101","author":"Koufman JA","year":"1991","journal-title":"Laryngoscope"},{"issue":"1","key":"ref17","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1097\/SLA.0000000000001907","article-title":"Diagnosis and Treatment of the Extraesophageal Manifestations of Gastroesophageal Reflux Disease","volume":"265","author":"Sidhwa F","year":"2017","journal-title":"Ann Surg"},{"issue":"3","key":"ref18","doi-asserted-by":"crossref","first-page":"720","DOI":"10.1002\/lary.27537","article-title":"Instruments evaluating the clinical findings of laryngopharyngeal reflux: a systematic review","volume":"129","author":"Lechien JR","year":"2019","journal-title":"Laryngoscope"},{"key":"ref19","doi-asserted-by":"crossref","first-page":"1313","DOI":"10.1097\/00005537-200108000-00001","article-title":"The validity and reliability of the reflux finding score (RFS)","volume":"111","author":"Belafsky PC","year":"2001","journal-title":"Laryngoscope"},{"issue":"25","key":"ref20","doi-asserted-by":"crossref","first-page":"3020","DOI":"10.3748\/wjg.v17.i25.3020","article-title":"Association of upper gastrointestinal symptoms with functional and clinical characteristics in elderly","volume":"17","author":"Pilotto A","year":"2011","journal-title":"World J Gastroenterol"},{"issue":"4","key":"ref21","doi-asserted-by":"crossref","first-page":"779","DOI":"10.1016\/j.otc.2018.03.007","article-title":"The Effects of Reflux on the Elderly: The Problems with Medications and Interventions","volume":"51","author":"Mendelsohn AH","year":"2018","journal-title":"Otolaryngol Clin North Am"},{"key":"ref22","doi-asserted-by":"crossref","first-page":"1534","DOI":"10.1111\/j.1532-5415.1998.tb01538.x","article-title":"Aging, esophageal motility, and gastroesophageal reflux disease","volume":"46","author":"Ferriolli E","year":"1998","journal-title":"J Am Geriatr Soc"},{"issue":"3","key":"ref23","doi-asserted-by":"crossref","first-page":"995","DOI":"10.1007\/s00405-012-2244-8","article-title":"Over-diagnosis of laryngopharyngeal reflux as the cause of hoarseness","volume":"270","author":"Thomas JP","year":"2013","journal-title":"Eur Arch Otorhinolaryngol"},{"issue":"1","key":"ref24","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1016\/j.jvoice.2018.08.018","article-title":"Voice Quality as Therapeutic Outcome in Laryngopharyngeal Reflux Disease: A Prospective Cohort Study","volume":"34","author":"Lechien JR","year":"2020","journal-title":"J Voice"},{"issue":"11","key":"ref25","doi-asserted-by":"crossref","first-page":"1947","DOI":"10.1097\/01.mlg.0000176547.90094.ac","article-title":"Correlation between symptoms and laryngeal signs in laryngopharyngeal reflux","volume":"115","author":"Qadeer MA","year":"2005","journal-title":"Laryngoscope"}],"container-title":["CoDAS"],"original-title":[],"link":[{"URL":"http:\/\/www.scielo.br\/pdf\/codas\/v32n5\/2317-1782-codas-32-05-e20180052.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,1,24]],"date-time":"2021-01-24T02:34:07Z","timestamp":1611455647000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.scielo.br\/scielo.php?script=sci_arttext&pid=S2317-17822020000500312&tlng=pt"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020]]},"references-count":25,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2020]]}},"alternative-id":["S2317-17822020000500312"],"URL":"https:\/\/doi.org\/10.1590\/2317-1782\/20202018052","relation":{},"ISSN":["2317-1782"],"issn-type":[{"type":"electronic","value":"2317-1782"}],"subject":[],"published":{"date-parts":[[2020]]},"article-number":"e20180052"}}