{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,23]],"date-time":"2026-06-23T14:50:56Z","timestamp":1782226256294,"version":"3.54.5"},"reference-count":21,"publisher":"Archives of Endocrinology and Metabolism","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Arch. Endocrinol. Metab."],"published-print":{"date-parts":[[2016,4]]},"DOI":"10.1590\/2359-3997000000068","type":"journal-article","created":{"date-parts":[[2015,8,26]],"date-time":"2015-08-26T22:49:15Z","timestamp":1440629355000},"page":"173-177","source":"Crossref","is-referenced-by-count":20,"title":["PEG-asparaginase induced severe hypertriglyceridemia"],"prefix":"10.20945","volume":"60","author":[{"given":"Rodolfo J.","family":"Galindo","sequence":"first","affiliation":[{"name":"Hofstra University, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Justin","family":"Yoon","sequence":"additional","affiliation":[{"name":"Hofstra University, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Craig","family":"Devoe","sequence":"additional","affiliation":[{"name":"Hofstra University, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alyson K.","family":"Myers","sequence":"additional","affiliation":[{"name":"Hofstra University, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"8510","reference":[{"issue":"5","key":"ref1","doi-asserted-by":"crossref","first-page":"833","DOI":"10.1517\/14712591003769808","article-title":"Peg-asparaginase for acute lymphoblastic leukemia","volume":"10","author":"Rytting M","year":"2010","journal-title":"Expert Opin Biol Ther"},{"issue":"15","key":"ref2","doi-asserted-by":"crossref","first-page":"2685","DOI":"10.1016\/j.ejca.2014.06.023","article-title":"Severe hypertriglyceridaemia during therapy for childhood acute lymphoblastic leukaemia","volume":"50","author":"Bhojwani D","year":"2014","journal-title":"Eur J Cancer"},{"issue":"12","key":"ref3","doi-asserted-by":"crossref","first-page":"2237","DOI":"10.3109\/10428194.2011.596963","article-title":"Prevention and management of asparaginase\/pegasparaginase-associated toxicities in adults and older adolescents: recommendations of an expert panel","volume":"52","author":"Stock W","year":"2011","journal-title":"Leuk Lymphoma"},{"issue":"5","key":"ref4","doi-asserted-by":"crossref","first-page":"1581","DOI":"10.1210\/jc.2007-0275","article-title":"Update on dyslipidemia","volume":"92","author":"Garg A","year":"2007","journal-title":"J Clin Endocrinol Metab"},{"issue":"6","key":"ref5","doi-asserted-by":"crossref","first-page":"1886","DOI":"10.1182\/blood.V89.6.1886","article-title":"Asparaginase-associated lipid abnormalities in children with acute lymphoblastic leukemia","volume":"89","author":"Parsons SK","year":"1997","journal-title":"Blood"},{"issue":"4","key":"ref6","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1002\/hon.2007","article-title":"Double-delayed intensification paediatric protocol without radiotherapy is an efficient treatment in adult lymphoblastic lymphoma","volume":"30","author":"Corre E","year":"2012","journal-title":"Hematol Oncol"},{"issue":"1","key":"ref7","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1016\/j.leukres.2010.04.002","article-title":"Outcome of 40 adults aged from 18 to 55 years with acute lymphoblastic leukemia treated with double-delayed intensification pediatric protocol","volume":"35","author":"Ha\u00efat S","year":"2011","journal-title":"Leuk Res"},{"issue":"9","key":"ref8","doi-asserted-by":"crossref","first-page":"912","DOI":"10.1097\/00007611-199909000-00013","article-title":"Drug-induced hypertriglyceridemia with and without pancreatitis","volume":"92","author":"Keung YK","year":"1999","journal-title":"South Med J"},{"issue":"6","key":"ref9","doi-asserted-by":"crossref","first-page":"1227","DOI":"10.1111\/j.1537-2995.2008.01663.x","article-title":"Plasmapheresis in asparaginase-induced hypertriglyceridemia","volume":"48","author":"Kfoury-Baz EM","year":"2008","journal-title":"Transfusion"},{"key":"ref10","article-title":"PEG-L-asparaginase induced hypertriglyceridemia","volume":"33","author":"Konig M","year":"2012","journal-title":"Endocr Rev"},{"issue":"6","key":"ref11","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1111\/j.1744-9987.2008.00647.x","article-title":"A case report of an adult with severe hyperlipidemia during acute lymphocytic leukemia induction therapy successfully treated with plasmapheresis","volume":"12","author":"Nakagawa M","year":"2008","journal-title":"Ther Apher Dial"},{"issue":"10","key":"ref12","doi-asserted-by":"crossref","first-page":"596","DOI":"10.1159\/000342690","article-title":"Conservative management of L-asparaginase-induced hypertriglyceridemia in an adult patient: a case report and review of the literature","volume":"35","author":"Seah J","year":"2012","journal-title":"Onkologie"},{"issue":"3","key":"ref13","doi-asserted-by":"crossref","first-page":"219","DOI":"10.4103\/0973-1482.57133","article-title":"Turbid serum in a patient of acute lymphoblastic leukemia on treatment \u2013 what to look for?","volume":"5","author":"Singh T","year":"2009","journal-title":"J Cancer Res Ther"},{"issue":"5","key":"ref14","doi-asserted-by":"crossref","first-page":"703","DOI":"10.1002\/pbc.22305","article-title":"Conservative treatment of L-asparaginase-associated lipid abnormalities in children with acute lymphoblastic leukemia","volume":"54","author":"Cohen H","year":"2010","journal-title":"Pediatr Blood Cancer"},{"issue":"8","key":"ref15","doi-asserted-by":"crossref","first-page":"1377","DOI":"10.1038\/sj.leu.2400703","article-title":"Transient hyperlipidemia during treatment of ALL with L-asparaginase is related to decreased lipoprotein lipase activity","volume":"11","author":"Hoogerbrugge N","year":"1997","journal-title":"Leukemia"},{"issue":"1","key":"ref16","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1007\/BF00442614","article-title":"The effect of L-asparaginase on lipid metabolism during induction chemotherapy of childhood lymphoblastic leukaemia","volume":"147","author":"Cremer P","year":"1988","journal-title":"Eur J Pediatr"},{"issue":"5","key":"ref17","first-page":"351","article-title":"Characterization of hypertriglyceridemia induced by L-asparaginase therapy for acute lymphoblastic leukemia and malignant lymphoma","volume":"27","author":"Tozuka M","year":"1997","journal-title":"Ann Clin Lab Sci"},{"issue":"41","key":"ref18","doi-asserted-by":"crossref","first-page":"26388","DOI":"10.1074\/jbc.273.41.26388","article-title":"Overexpression and accumulation of apolipoprotein E as a cause of hypertriglyceridemia","volume":"273","author":"Huang Y","year":"1998","journal-title":"J Biol Chem"},{"issue":"6","key":"ref19","doi-asserted-by":"crossref","first-page":"571","DOI":"10.1007\/s12185-011-0966-9","article-title":"Symptomatic severe hypertriglyceridaemia with asparaginase therapy in acute lymphoblastic leukaemia (ALL) and lymphoblastic lymphoma: is rechallenging safe?","volume":"94","author":"Lashkari HP","year":"2011","journal-title":"Int J Hematol"},{"issue":"6","key":"ref20","doi-asserted-by":"crossref","first-page":"630","DOI":"10.1016\/j.jacl.2014.09.004","article-title":"Extreme hypertriglyceridemia managed with insulin","volume":"8","author":"Thuzar M","year":"2014","journal-title":"J Clin Lipidol"},{"key":"ref21","first-page":"1","author":"Therrien R","year":"2013"}],"container-title":["Archives of Endocrinology and Metabolism"],"original-title":[],"link":[{"URL":"http:\/\/www.scielo.br\/pdf\/aem\/v60n2\/2359-3997-aem-2359-3997000000068.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,9,7]],"date-time":"2020-09-07T16:32:46Z","timestamp":1599496366000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.scielo.br\/scielo.php?script=sci_arttext&pid=S2359-39972016000200173&lng=en&tlng=en"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,4]]},"references-count":21,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2016,4]]}},"alternative-id":["S2359-39972016000200173"],"URL":"https:\/\/doi.org\/10.1590\/2359-3997000000068","relation":{},"ISSN":["2359-3997"],"issn-type":[{"value":"2359-3997","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,4]]}}}