{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,28]],"date-time":"2025-10-28T10:05:53Z","timestamp":1761645953412},"reference-count":44,"publisher":"EDITORA SCIENTIFIC","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rev. Bras. Psiquiatr."],"published-print":{"date-parts":[[2003,9]]},"abstract":"<jats:p>OBJECTIVE: The regulations on the advertisement of medications aim to encourage and promote an improved health care and the rational use of medications. The objective of this paper is to evaluate the influence of three regulations on the advertisement of medications: the \"Export act\", published in the United States in 1986; the \"WHO's Criteria\", published in 1988, and the Resolution 102\/2000 of the Collegiate Board of Directors of the ANVISA (Ag\u00eancia Nacional de Vigil\u00e2ncia Sanit\u00e1ria- Brazilian Sanitary Surveillance Agency), on the advertisement of psychoactive medications. METHOD: We collected advertisements that were published in Brazilian psychiatric journals before and after the regulations were established. The contents of the advertisements were analyzed according to a program created based on the regulation's demands. RESULTS: In the 118 analyzed issues there were 199 different advertisements on 85 psychotropic drugs. We observed that, regardless the studied medication, the information about restrictions of use, such as adverse drug reactions, interactions, contraindications, warnings and precautions, does not appear very often, and when it does, its print sizes were smaller than that of the information favoring the use, such as indication, presentation and dosage. After the publication of the regulations, only 38.2% of the advertisements had all the essential technical information, and 35.3% were irregular in some way. CONCLUSION: The data suggest that there was very little influence of the regulations on the advertisement of psychotropic drugs in Brazil. Consequently, other control measures are necessary in addition to the regulations.<\/jats:p>","DOI":"10.1590\/s1516-44462003000300006","type":"journal-article","created":{"date-parts":[[2005,4,26]],"date-time":"2005-04-26T16:17:48Z","timestamp":1114532268000},"page":"146-155","source":"Crossref","is-referenced-by-count":6,"title":["Influence of the legislation on the advertisement of psychoactive medications in Brazil"],"prefix":"10.47626","volume":"25","author":[{"given":"Patr\u00edcia de Carvalho","family":"Mastroianni","sequence":"first","affiliation":[{"name":"Federal University of S\u00e3o Paulo, Brazil"}]},{"given":"Jose Carlos Fernandez","family":"Galdur\u00f3z","sequence":"additional","affiliation":[{"name":"University of S\u00e3o Paulo, Brazil"}]},{"given":"Elisaldo Ara\u00fajo","family":"Carlini","sequence":"additional","affiliation":[{"name":"University of S\u00e3o Paulo, 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1983-8: a critical analysis of self regulation","volume":"300","author":"Herxheimer A","year":"1990","journal-title":"BMJ","ISSN":"http:\/\/id.crossref.org\/issn\/0959-8138","issn-type":"print"},{"key":"ref7","article-title":"Resolu\u00e7\u00e3o da Diretoria Colegiada n\u00b0 102","year":"2000","journal-title":"Di\u00e1rio Oficial da Rep\u00fablica Federativa do Brasil"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"365","DOI":"10.2190\/7WMN-8CT1-DHT8-D1AD","article-title":"The changing image of prescription drug advertisements","volume":"12","author":"Saporito R","year":"1982","journal-title":"J Drug Educ","ISSN":"http:\/\/id.crossref.org\/issn\/0047-2379","issn-type":"print"},{"key":"ref9","first-page":"378","article-title":"Pharmacists'and physicians'attitudes toward pharmaceutical marketing practices","volume":"51","author":"Poirier TI","year":"1994","journal-title":"Am J Hosp Pharm","ISSN":"http:\/\/id.crossref.org\/issn\/0002-9289","issn-type":"print"},{"issue":"4","key":"ref10","first-page":"70","article-title":"Utiliza\u00e7\u00e3o de medicamentos","volume":"I","author":"Carlini EA","year":"1981","journal-title":"Boletim de Informa\u00e7\u00f5es"},{"key":"ref11","first-page":"99","article-title":"Perfil farmacoterap\u00eautico de prescri\u00e7\u00f5es m\u00e9dicas hospitalares","volume":"37 Supl 2","author":"Sebasti\u00e3o ECO","year":"2001","journal-title":"Rev Bras Ci\u00eanc Farm"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/0037-7856(73)90135-2","article-title":"The quality of drug advertisements in two Finnish medical journals: A comparison between psychotropic and other drug advertisements","volume":"7","author":"Hemminki E.","year":"1973","journal-title":"Soc Sci Med","ISSN":"http:\/\/id.crossref.org\/issn\/0037-7856","issn-type":"print"},{"key":"ref13","first-page":"152","article-title":"O uso e a propaganda de medicamentos: Exemplos com psicotr\u00f3picos","volume":"5","author":"Carlini EA","year":"1983","journal-title":"Rev Ass Bras Psiq"},{"key":"ref14","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1590\/S0034-89102000000200018","article-title":"Pol\u00edtica Nacional de Medicamentos","volume":"34","year":"2000","journal-title":"Rev Sa\u00fade P\u00fablica"},{"key":"ref15","first-page":"48","article-title":"A publicidade das drogas psicotr\u00f3picas e a pr\u00e1tica m\u00e9dica","volume":"12","author":"Villarim Neto A","year":"1993","journal-title":"CCS","ISSN":"http:\/\/id.crossref.org\/issn\/0100-8528","issn-type":"print"},{"key":"ref16","series-title":"O desafio do conhecimento: pesquisa qualitativa","author":"Minayo MCS","year":"1998","edition":"2"},{"key":"ref17","series-title":"An\u00e1lise de conte\u00fado","author":"Bardin L","year":"1977"},{"key":"ref18","doi-asserted-by":"crossref","first-page":"387","DOI":"10.2190\/E81E-T164-T0BG-RM05","article-title":"The construction of gender and mental health in Nordic psychotropic-drug advertising","volume":"30","author":"L\u00f6vdahl U","year":"2000","journal-title":"Int J Health Serv","ISSN":"http:\/\/id.crossref.org\/issn\/0020-7314","issn-type":"print"},{"key":"ref19","doi-asserted-by":"crossref","first-page":"S1","DOI":"10.1590\/S1516-44461999000500002","article-title":"Epidemiologia e impacto social","volume":"21","author":"Lima MS","year":"1999","journal-title":"Rev Bras Psiquiatr"},{"key":"ref20","first-page":"339","article-title":"Padr\u00e3o de prescri\u00e7\u00e3o de psicof\u00e1rmacos no ambulat\u00f3rio de psiquiatria do CEJBF: avaliando modifica\u00e7\u00f5es","volume":"41","author":"Iserhard R","year":"1992","journal-title":"J Bras Psiquiatr","ISSN":"http:\/\/id.crossref.org\/issn\/0047-2085","issn-type":"print"},{"key":"ref21","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1590\/S0102-311X1998000100016","article-title":"An\u00e1lise da adequa\u00e7\u00e3o das propagandas de medicamentos dirigidas \u00e0 categoria m\u00e9dica distribu\u00eddas no Sul do Brasil","volume":"14","author":"Pizzol FD","year":"1998","journal-title":"Cad Sa\u00fade P\u00fablica"},{"key":"ref22","doi-asserted-by":"crossref","first-page":"392","DOI":"10.1136\/ewjm.174.6.391","article-title":"Do drug advertisements in Russian medical journals provide essential information for safe prescribing?","volume":"174","author":"Vlassov V.","year":"2001","journal-title":"West J Med","ISSN":"http:\/\/id.crossref.org\/issn\/0093-0415","issn-type":"print"},{"key":"ref23","first-page":"315","article-title":"Material informativo entregado por los agentes de propaganda medica","volume":"61","author":"Mejia R","year":"2001","journal-title":"Medicina","ISSN":"http:\/\/id.crossref.org\/issn\/0025-7680","issn-type":"print"},{"key":"ref24","doi-asserted-by":"crossref","first-page":"912","DOI":"10.7326\/0003-4819-116-11-912","article-title":"Pharmaceutical advertisements in leading medical journals: experts' assessments","volume":"116","author":"Wilkes MS","year":"1992","journal-title":"Ann Intern Med","ISSN":"http:\/\/id.crossref.org\/issn\/0003-4819","issn-type":"print"},{"key":"ref25","doi-asserted-by":"crossref","first-page":"671","DOI":"10.5694\/j.1326-5377.1994.tb126915.x","article-title":"Pharmaceutical advertisements in Australian medical publications: have they improved?","volume":"161","author":"Carandang ED","year":"1994","journal-title":"Med J Aust","ISSN":"http:\/\/id.crossref.org\/issn\/0025-729X","issn-type":"print"},{"key":"ref26","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1067\/mcp.2000.111947","article-title":"The control of prescription drug advertising: a controversial issue","volume":"68","author":"Jaillon P","year":"2000","journal-title":"Clin Pharmacol Ther","ISSN":"http:\/\/id.crossref.org\/issn\/0009-9236","issn-type":"print"},{"key":"ref27","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/0037-7856(75)90154-7","article-title":"Sex differences in the content and style of medical advertisements","volume":"9","author":"Prather J","year":"1975","journal-title":"Soc Sci Med","ISSN":"http:\/\/id.crossref.org\/issn\/0037-7856","issn-type":"print"},{"key":"ref28","first-page":"68","article-title":"An\u00e1lise da prescri\u00e7\u00e3o e dispensa\u00e7\u00e3o de medicamentos psicotr\u00f3picos em dois munic\u00edpios do Estado de S\u00e3o Paulo","volume":"24","author":"Noto AR","year":"2002","journal-title":"Rev Bras Psiquiatr"},{"key":"ref29","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1016\/0037-7856(77)90104-4","article-title":"Rationality of appeals used in the promotion of psychotropic drugs: A comparison of male and female models","volume":"11","author":"Smith MC","year":"1977","journal-title":"Soc Sci Med","ISSN":"http:\/\/id.crossref.org\/issn\/0037-7856","issn-type":"print"},{"key":"ref30","first-page":"123","article-title":"Psychiatrists opinions of psychotropic drug advertisements","volume":"13","author":"Lion JR","year":"1979","journal-title":"Soc Sci","ISSN":"http:\/\/id.crossref.org\/issn\/0167-2320","issn-type":"print"},{"key":"ref31","first-page":"265","article-title":"Consumo de benzodiazep\u00ednicos em Porto Alegre","volume":"40","author":"Wortmann AC","year":"1994","journal-title":"Rev Assoc Med Bras","ISSN":"http:\/\/id.crossref.org\/issn\/0004-5241","issn-type":"print"},{"key":"ref32","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1016\/0277-9536(91)90349-H","article-title":"Advertising for psychotropic drugs in the Nordic countries: metaphors, gender and life situations","volume":"32","author":"Riska E","year":"1991","journal-title":"Soc Sci Med","ISSN":"http:\/\/id.crossref.org\/issn\/0037-7856","issn-type":"print"},{"key":"ref33","series-title":"Health Action International: Psychotropics - tales of dependence","author":"Chetley A","year":"1993"},{"key":"ref34","doi-asserted-by":"crossref","first-page":"867","DOI":"10.1016\/0277-9536(91)90242-5","article-title":"The decontextualization of mental illness: the portrayal of work in psychiatric drug advertisements","volume":"32","author":"Kleinman DL","year":"1991","journal-title":"Soc Sci Med","ISSN":"http:\/\/id.crossref.org\/issn\/0037-7856","issn-type":"print"},{"key":"ref35","series-title":"Essential psycopharmacology","first-page":"335","volume-title":"Drug treatments for obsessive-compulsive disorder, panic disorder and phobic disorders","author":"Sthahl SM","year":"2000","edition":"2"},{"key":"ref36","first-page":"455","article-title":"Sleep complaints in S\u00e3o Paulo city: a comparison between the years 1987 and 1995","volume":"26","author":"Palma 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Med","ISSN":"http:\/\/id.crossref.org\/issn\/0003-4819","issn-type":"print"},{"key":"ref41","first-page":"47","article-title":"Methodological quality and relevance of references in pharmaceutical advertisements in a Canadian medical journal","volume":"151","author":"Lexchin J","year":"1994","journal-title":"CMAJ","ISSN":"http:\/\/id.crossref.org\/issn\/0820-3946","issn-type":"print"},{"key":"ref42","doi-asserted-by":"crossref","first-page":"607","DOI":"10.1016\/S0009-9236(98)90083-2","article-title":"The Food and Drug Administration's regulation of drug labeling, advertising, and promotion: looking back and looking ahead","volume":"63","author":"Hayes TA","year":"1998","journal-title":"Clin Pharmacol Ther","ISSN":"http:\/\/id.crossref.org\/issn\/0009-9236","issn-type":"print"},{"key":"ref43","first-page":"197","article-title":"Evidence-based advertising: A survey of four major journals","volume":"14","author":"Gutknecht DR","year":"2001","journal-title":"J Am Board Fam 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