{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,20]],"date-time":"2025-05-20T04:06:34Z","timestamp":1747713994944,"version":"3.40.5"},"reference-count":28,"publisher":"FapUNIFESP (SciELO)","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["An. Bras. Dermatol."],"published-print":{"date-parts":[[2013,10]]},"abstract":"<jats:p> BACKGROUND:  Sepsis is a common cause of morbidity and mortality among hospitalized patients. The prevalence of this condition has increased significantly in different parts of the world. Patients admitted to dermatology wards often have severe loss of skin barrier and use systemic corticosteroids, which favor the development of sepsis.    OBJECTIVES:  To evaluate the prevalence of sepsis among patients admitted to a dermatology ward compared to that among patients admitted to an internal medicine ward.    METHODS:  It is a cross-sectional, observational, comparative study that was conducted at Hospital Santa Casa de Belo Horizonte. Data were collected from all patients admitted to four hospital beds at the dermatology and internal medicine wards between July 2008 and July 2009. Medical records were analyzed for the occurrence of sepsis, dermatologic diagnoses, comorbidities, types of pathogens and most commonly used antibiotics.    RESULTS:  We analyzed 185 medical records. The prevalence of sepsis was 7.6% among patients admitted to the dermatology ward and 2.2% (p = 0.10) among those admitted to the internal medicine ward. Patients with comorbidities, diabetes mellitus and cancer did not show a higher incidence of sepsis. The main agent found was Staphylococcus aureus, and the most commonly used antibiotics were ciprofloxacin and oxacillin. There was a significant association between sepsis and the use of systemic corticosteroids (p &lt;0.001).    CONCLUSION:  It becomes clear that epidemiological studies on sepsis should be performed more extensively and accurately in Brazil so that efforts to prevent and treat this serious disease can be made more effectively.<\/jats:p>","DOI":"10.1590\/abd1806-4841.20131912","type":"journal-article","created":{"date-parts":[[2013,11,25]],"date-time":"2013-11-25T13:35:47Z","timestamp":1385386547000},"page":"739-747","source":"Crossref","is-referenced-by-count":2,"title":["Comparative study of the prevalence of sepsis in patients admitted to dermatology and internal medicine wards"],"prefix":"10.1590","volume":"88","author":[{"given":"Luiz Mauricio Costa","family":"Almeida","sequence":"first","affiliation":[{"name":"Santa Casa de Belo Horizonte,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michelle dos Santos","family":"Diniz","sequence":"additional","affiliation":[{"name":"Santa Casa de Belo Horizonte,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lorena dos Santos","family":"Diniz","sequence":"additional","affiliation":[{"name":"San Jose Hospital,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jackson","family":"Machado-Pinto","sequence":"additional","affiliation":[{"name":"Hospital Santa Casa de Belo Horizonte; College of Medical Sciences of Minas Gerais,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francisco Chagas Lima","family":"Silva","sequence":"additional","affiliation":[{"name":"Hospital Santa Casa de Belo Horizonte,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"530","reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"1644","DOI":"10.1378\/chest.101.6.1644","article-title":"Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. The ACCP\/SCCM Consensus Conference Committee. American College of Chest Physicians\/ Society of Critical Care Medicine","volume":"101","author":"Bone RC","year":"1992","journal-title":"Chest"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1186\/cc1843","article-title":"Usefulness of procalcitonin for diagnosis of sepsis in the intensive care unit","volume":"7","author":"BalcI C","year":"2003","journal-title":"Crit Care"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"659","DOI":"10.1056\/NEJM198709103171102","article-title":"Effect of high-dose glucocorticoid therapy on mortality in patients with clinical signs of systemic sepsis. The Veterans Administration Systemic Sepsis Cooperative Study Group","volume":"317","year":"1987","journal-title":"N Engl J Med"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1186\/1471-2334-9-115","article-title":"Retrospective analysis of nosocomial infections in the intensive care unit of a tertiary hospital in China during 2003 and 2007","volume":"9","author":"Ding JG","year":"2009","journal-title":"BMC Infect Dis"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"367","DOI":"10.4103\/0378-6323.35753","article-title":"Study of sepsis in dermatology ward: a preliminary report","volume":"73","author":"Sharma VK","year":"2007","journal-title":"Indian J Dermatol Venereol Leprol"},{"year":"2000","series-title":"Applied logistic regression","author":"Hosmer DW","key":"ref6"},{"key":"ref7","first-page":"13","article-title":"Clinical features of pemphigus","volume":"1","author":"Ahmed AR","year":"1983","journal-title":"ClinDerm"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1136\/pgmj.2009.083824","article-title":"Systemic inflammatory response syndrome in diseases of the skin","volume":"86","author":"Thomas M","year":"2010","journal-title":"Postgrad Med J"},{"key":"ref9","first-page":"S564","article-title":"The epidemiology of the systemic inflammatory response","volume":"26","author":"Brun-Buisson C","year":"2000","journal-title":"Intesive Care Med"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1001\/jama.1995.03520260039030","article-title":"The natural history of the systemic inflammatory response syndrome (SIRS). A prospective study","volume":"273","author":"Rangel-Frausto MS","year":"1995","journal-title":"JAMA"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"968","DOI":"10.1378\/chest.129.4.968","article-title":"Severe sepsis in community-acquired pneumonia: when does it happen and do systemic inflammatory response syndrome criteria help predict course?","volume":"129","author":"Dremsizov T","year":"2006","journal-title":"Chest"},{"key":"ref12","first-page":"926","article-title":"Guidelines for the management of pemphigus vulgaris","volume":"149","author":"Harman KE","year":"2003","journal-title":"Br J Dermatol"},{"key":"ref13","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1016\/S0190-9622(82)70111-2","article-title":"Death in pemphigus","volume":"7","author":"Ahmed AR","year":"1982","journal-title":"J Am Acad Dermatol"},{"key":"ref14","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1038\/jid.2011.249","article-title":"Incidence, mortality, and causes of death of patients with pemphigus in Taiwan: A nationwide population-based study","volume":"132","author":"Huang YH","year":"2012","journal-title":"J Invest Dermatol"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"1303","DOI":"10.1097\/00003246-200107000-00002","article-title":"Epidemiology of severe sepsis in the United States: Analysis of incidence, outcome, and associated costs of care","volume":"29","author":"Angus DC","year":"2001","journal-title":"Crit Care Med"},{"year":"2011","series-title":"Inpatient care for sepse or sepsis: A challenge for patients and hospitals. 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