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We report the case of a patient with chronic hepatitis C who presented with the signs and symptoms of borderline tuberculoid leprosy and type 1 reaction four months after the start of treatment with a pegylated interferon\/ribavirin combination.<\/jats:p>","DOI":"10.1590\/abd1806-4841.20131986","type":"journal-article","created":{"date-parts":[[2014,1,30]],"date-time":"2014-01-30T19:47:12Z","timestamp":1391111232000},"page":"109-112","source":"Crossref","is-referenced-by-count":8,"title":["Borderline tuberculoid leprosy and type 1 leprosy reaction in a hepatitis C patient during treatment with interferon and ribavirin"],"prefix":"10.1590","volume":"88","author":[{"given":"M\u00f4nica","family":"Santos","sequence":"first","affiliation":[{"name":"Alfredo da Matta Foundation,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emily dos Santos","family":"Franco","sequence":"additional","affiliation":[{"name":"Get\u00falio Vargas University Hospital,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paulo Luis da Costa","family":"Ferreira","sequence":"additional","affiliation":[{"name":"Tropical Medicine of Amazonas Foundation,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wornei Silva Miranda","family":"Braga","sequence":"additional","affiliation":[{"name":"Tropical Medicine of Amazonas Foundation,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"530","reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1067\/mjd.2001.109311","article-title":"Hepatitis C: a review and update","volume":"44","author":"Bonkovsky HL","year":"2001","journal-title":"J Am Acad Dermatol"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"2095","DOI":"10.1016\/S0140-6736(03)15109-4","article-title":"Viral hepatitis C","volume":"362","author":"Poynard T","year":"2003","journal-title":"Lancet"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1016\/j.jhep.2003.10.009","article-title":"Extrahepatic disease manifestations of HCV infection: some current issues","volume":"40","author":"Agnello V","year":"2004","journal-title":"J Hepatol"},{"key":"ref4","first-page":"53","article-title":"Altera\u00e7\u00f5es dermatol\u00f3gicas na hepatite C","volume":"8","author":"Caramez C","year":"2010","journal-title":"Rev Bras Clin Med"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1016\/S0733-8635(02)00013-X","article-title":"Hepatitis C and the skin","volume":"20","author":"Jackson JM","year":"2002","journal-title":"Dermatol Clin"},{"key":"ref6","first-page":"343","article-title":"Immunology of leprosy","volume":"83","author":"Mendon\u00e7a VA","year":"2008","journal-title":"An Bras Dermatol"},{"key":"ref7","first-page":"367","article-title":"Contribution to diagnosis and management of reactional states: a practical approach","volume":"81","author":"Nery JAC","year":"2006","journal-title":"An Bras Dermatol"},{"key":"ref8","first-page":"365","article-title":"Imunopatologia da hansen\u00edase: a complexidade dos mecanismos da resposta imune do hospedeiro ao Mycobacterium leprae","volume":"5","author":"Goulart IM","year":"2002","journal-title":"Rev Soc Bras Med Trop"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1016\/j.jhep.2011.08.006","article-title":"Dermatological side effects of hepatitis C and its treatment: patient management in the era of direct-acting antivirals","volume":"56","author":"Cacoub P","year":"2012","journal-title":"J Hepatol"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"546","DOI":"10.1590\/S0037-86822007000500011","article-title":"Caracter\u00edsticas da rea\u00e7\u00e3o tipo 1 e associa\u00e7\u00e3o com v\u00edrus B e C da hepatite na hansen\u00edase","volume":"40","author":"Rego VPA","year":"2007","journal-title":"Rev Soc Bras Med Trop"}],"container-title":["Anais Brasileiros de Dermatologia"],"original-title":[],"link":[{"URL":"http:\/\/www.scielo.br\/pdf\/abd\/v88n6s1\/0365-0596-abd-88-06-s1-0109.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,5,19]],"date-time":"2025-05-19T15:00:41Z","timestamp":1747666841000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.scielo.br\/scielo.php?script=sci_arttext&pid=S0365-05962013000800109&lng=en&tlng=en"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,12]]},"references-count":10,"journal-issue":{"issue":"6 suppl 1","published-print":{"date-parts":[[2013,12]]}},"alternative-id":["S0365-05962013000800109"],"URL":"https:\/\/doi.org\/10.1590\/abd1806-4841.20131986","relation":{},"ISSN":["0365-0596"],"issn-type":[{"type":"electronic","value":"0365-0596"}],"subject":[],"published":{"date-parts":[[2013,12]]}}}