{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,29]],"date-time":"2025-08-29T10:42:34Z","timestamp":1756464154376,"version":"3.40.5"},"reference-count":7,"publisher":"FapUNIFESP (SciELO)","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["An. Bras. Dermatol."],"published-print":{"date-parts":[[2013,12]]},"abstract":"<jats:p>Granular cell tumor is a rare benign neoplasm of neural origin. We report the case of a female patient, 27 years old presenting a brown-red nodule in the right arm, which pathological examination showed to be formed by polygonal cells with eosinophilic granular cytoplasm and immunohistochemistry positive for S100 protein and CD68. Granular cell tumor is usually solitary and in half the cases located in the head and neck areas, 30% of these in the tongue. It is most frequent between the third and fifth decades of life in women and people of African-American ethnicity. Its origination is controversial, including the possible origins in muscle, fibroblasts, neural crest, neural sheath or histiocytes. The positivity for S-100 and CD68 suggest the neural origin.<\/jats:p>","DOI":"10.1590\/abd1806-4841.20132772","type":"journal-article","created":{"date-parts":[[2014,2,14]],"date-time":"2014-02-14T14:05:27Z","timestamp":1392386727000},"page":"1005-1007","source":"Crossref","is-referenced-by-count":5,"title":["Case for diagnosis"],"prefix":"10.1590","volume":"88","author":[{"given":"Thaiane Lima","family":"Lage","sequence":"first","affiliation":[{"name":"Par\u00e1 Federal University,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mario Fernando Ribeiro de","family":"Miranda","sequence":"additional","affiliation":[{"name":"Par\u00e1 Federal University,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maraya de Jesus Semblano","family":"Bittencourt","sequence":"additional","affiliation":[{"name":"Par\u00e1 Federal University,  Brazil; State Universitary Center of Par\u00e1"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carolina Moraes","family":"Dias","sequence":"additional","affiliation":[{"name":"Par\u00e1 Federal University,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amanda Magno de","family":"Parij\u00f3s","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Theisla Kely Azevedo","family":"Raiol","sequence":"additional","affiliation":[{"name":"Santa Casa de Miseric\u00f3rdia do Par\u00e1 Foundation,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"530","reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1080\/019131299281545","article-title":"Granular cell tumor: a review of the pathology and histogenesis","volume":"23","author":"Ord\u00f3\u00f1ez NG","year":"1999","journal-title":"Ultrastruct Pathol"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"246","DOI":"10.1007\/s00404-005-0054-6","article-title":"Granular cell tumor of the vulva: six new cases","volume":"273","author":"Levavi H","year":"2006","journal-title":"Arch Gynecol Obstet"},{"key":"ref3","first-page":"343","article-title":"Multiple cutaneous granular cell tumors: a case report and review of the literature","volume":"69","author":"Gross VL","year":"2002","journal-title":"Cutis"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"695","DOI":"10.1111\/j.1365-2230.2011.04241.x","article-title":"An asymptomatic, progressive, ulcerative nodule over the anterolateral surface of the left upper arm","volume":"37","author":"Sehgal VN","year":"2012","journal-title":"Clin Exp Dermatol"},{"key":"ref5","first-page":"215","article-title":"Tumor de c\u00e9lulas granulares no p\u00e9 (tumor de Abrikossoff): localiza\u00e7\u00e3o infreq\u00fcente de tumor relativamente raro (Foot granular cell tumor (Abrikossoff's tumor): unusual location of a relatively uncommon tumor)","volume":"76","author":"Brand\u00e3o M","year":"2001","journal-title":"An Bras Dermatol"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1016\/j.anndiagpath.2010.01.005","article-title":"Morphologic spectrum, immunohistochemical analysis, and clinical features of a series of granular cell tumors of soft tissues: a study from a tertiary referral cancer center","volume":"14","author":"Rekhi B","year":"2010","journal-title":"Ann Diagn Pathol"},{"key":"ref7","first-page":"126","article-title":"Cutaneous granular cell tumor: a clinical and pathologic analysis of 34 cases","volume":"100","author":"Torrijos-Aguilar A","year":"2009","journal-title":"Actas Dermosifiliogr"}],"container-title":["Anais Brasileiros de Dermatologia"],"original-title":[],"link":[{"URL":"http:\/\/www.scielo.br\/pdf\/abd\/v88n6\/0365-0596-abd-88-06-1005.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,5,19]],"date-time":"2025-05-19T15:00:41Z","timestamp":1747666841000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.scielo.br\/scielo.php?script=sci_arttext&pid=S0365-05962013000601005&lng=en&tlng=en"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,12]]},"references-count":7,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2013,12]]}},"alternative-id":["S0365-05962013000601005"],"URL":"https:\/\/doi.org\/10.1590\/abd1806-4841.20132772","relation":{},"ISSN":["0365-0596"],"issn-type":[{"type":"electronic","value":"0365-0596"}],"subject":[],"published":{"date-parts":[[2013,12]]}}}