{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T15:16:44Z","timestamp":1753888604272,"version":"3.41.2"},"reference-count":28,"publisher":"FapUNIFESP (SciELO)","license":[{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"am","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acta Cir. Bras."],"abstract":"<jats:p>ABSTRACT  Purpose: To evaluate the angiographic outcomes of the Optima\u2122 coil system in the endovascular treatment of saccular intracranial aneurysms to present real-world experiences.  Methods: The study encompassed patients with both ruptured and unruptured aneurysms who underwent treatment with the Optima\u2122 coil system. A retrospective analysis was conducted to examine patient and aneurysm characteristics, complication rates, and angiographic outcomes.  Results: The total of 326 Optima\u2122 coil implantations was performed in 64 aneurysms, with a mean maximum diameter of 7.49 \u00b1 3.08 mm (range: 2.5\u201316.5 mm), among 64 patients (37 females and 27 males, mean age: 53.34 \u00b1 14 years old). The average number of implanted coils was 5.06 \u00b1 1.73. The mean packing density was 26.2% (range = 19.2\u201334.6), observed to be significantly higher in aneurysms with complete occlusion and neck remnants compared to those with a residual dome (p &lt; 0.01). The mean follow-up period was 15.9 \u00b1 8.1 months. One case (1.5%) reported a coil malfunction attributed to coil stretching. The mortality rate was 3.1% (n = 2).  Conclusion: The Optima\u2122 coil system exhibited safety and efficacy in the endovascular treatment of both ruptured and unruptured intracranial aneurysms, demonstrating favorable angiographic outcomes. Nevertheless, further studies are necessary to validate these results over the long term.<\/jats:p>","DOI":"10.1590\/acb403425","type":"journal-article","created":{"date-parts":[[2025,5,11]],"date-time":"2025-05-11T02:58:44Z","timestamp":1746932324000},"source":"Crossref","is-referenced-by-count":0,"title":["Initial experiences of the Optima\u2122 coil system in intracranial aneurysm treatment: surgical and interventional approach to safety and efficacy in terms of cerebral arteries"],"prefix":"10.1590","volume":"40","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0875-6147","authenticated-orcid":false,"given":"Bekir S\u0131tk\u0131 Said","family":"Ulusoy","sequence":"first","affiliation":[{"name":"University of Health Sciences,  Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6258-3078","authenticated-orcid":false,"given":"\u00c7etin Murat","family":"Altay","sequence":"additional","affiliation":[{"name":"University of Health Sciences,  Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6220-3207","authenticated-orcid":false,"given":"Mehmet","family":"Onay","sequence":"additional","affiliation":[{"name":"University of Health Sciences,  Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5220-1232","authenticated-orcid":false,"given":"Ali Burak","family":"Binboga","sequence":"additional","affiliation":[{"name":"University of Health Sciences,  Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1251-1292","authenticated-orcid":false,"given":"Murat","family":"Kaya","sequence":"additional","affiliation":[{"name":"University of Health Sciences,  Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"530","published-online":{"date-parts":[[2025]]},"reference":[{"issue":"47","key":"ref1","article-title":"Endovascular treatment of multiple intracranial aneurysms","volume":"102","author":"Wang JW","year":"2023","journal-title":"Medicine (Baltimore)"},{"issue":"3","key":"ref2","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1055\/s-0039-1685513","article-title":"Endovascular retreatment of cerebral aneurysms previously treated with endovascular embolization","volume":"81","author":"Li H","year":"2020","journal-title":"J Neurol Surg A Cent Eur Neurosurg"},{"issue":"3","key":"ref3","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1177\/1591019919897446","article-title":"Safety and efficacy of endovascular treatment of ruptured tiny cerebral aneurysms compared with ruptured larger aneurysms","volume":"26","author":"Wang JW","year":"2020","journal-title":"Interv Neuroradiol"},{"issue":"2","key":"ref4","doi-asserted-by":"crossref","first-page":"470","DOI":"10.1161\/01.STR.30.2.470","article-title":"Treatment of intracranial aneurysms by embolization with coils: a systematic review","volume":"30","author":"rilstra EH","year":"1999","journal-title":"Stroke"},{"issue":"1","key":"ref5","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3171\/2009.2.JNS081039","article-title":"History of the genesis of detachable coils: a review","volume":"111","author":"Guglielmi G.","year":"2009","journal-title":"J Neurosurg"},{"issue":"Suppl.1","key":"ref6","doi-asserted-by":"crossref","first-page":"i69","DOI":"10.1136\/jnis.2011.004978.rep","article-title":"Treatment of ruptured and unruptured cerebral aneurysms in the USA: a paradigm shift","volume":"10","author":"Lin N","year":"2018","journal-title":"J Neurointerv Surg"},{"issue":"1","key":"ref7","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1177\/0003319717700503","article-title":"Current treatment strategies for intracranial aneurysms: an overview","volume":"69","author":"Zhao J","year":"2018","journal-title":"Angiology"},{"issue":"6","key":"ref8","doi-asserted-by":"crossref","first-page":"1235","DOI":"10.1097\/00006123-199712000-00002","article-title":"Safety and efficacy of endovascular treatment of acutely ruptured aneurysms","volume":"41","author":"Raymond J","year":"1997","journal-title":"Neurosurgery"},{"issue":"Suppl.1","key":"ref9","first-page":"A1","article-title":"Early experience with optima and optimax coil system in neuroendovascular procedures: A single-center case series of 20 patients","volume":"15","author":"Abdelsalam A","year":"2023","journal-title":"J NeuroIntervent Surg"},{"series-title":"Appraising the embolization of aneurysms using Balt Optima\u2122 Coil System (APPLY Study)","key":"ref10"},{"series-title":"Intracranial aneurysms treatment with the OPTIMA Coil System","key":"ref11"},{"issue":"9342","key":"ref12","doi-asserted-by":"crossref","first-page":"1267","DOI":"10.1016\/S0140-6736(02)11314-6","article-title":"International Subarachnoid Aneurysm Trial (ISAT) of neurosurgical clipping versus endovascular coiling in 2143 patients with ruptured intracranial aneurysms: a randomised trial","volume":"360","author":"Molyneux A","year":"2002","journal-title":"Lancet"},{"issue":"7","key":"ref13","doi-asserted-by":"crossref","first-page":"496","DOI":"10.1136\/neurintsurg-2014-011258","article-title":"An update to the Raymond\u2013Roy occlusion classification of intracranial aneurysms treated with coil embolization","volume":"7","author":"Mascitelli JR","year":"2015","journal-title":"J Neurointerv Surg"},{"issue":"9","key":"ref14","doi-asserted-by":"crossref","first-page":"927","DOI":"10.1136\/neurintsurg-2015-012035","article-title":"Validation of the modified Raymond\u2013Roy classification for intracranial aneurysms treated with coil embolization","volume":"8","author":"Stapleton CJ","year":"2016","journal-title":"J Neurointerv Surg"},{"issue":"Suppl.3","key":"ref15","doi-asserted-by":"crossref","first-page":"S132","DOI":"10.1016\/j.acra.2021.05.020","article-title":"Targeted and staged treatment for ruptured wide-neck intracranial aneurysms: bleb coiling strategy as a new approach","volume":"29","author":"Onay M","year":"2022","journal-title":"Acad Radiol"},{"issue":"1","key":"ref16","first-page":"29","article-title":"In vitro evaluation of coils for endovascular therapy","volume":"17","author":"Marks MP","year":"1996","journal-title":"Am J Neuroradiol"},{"issue":"12","key":"ref17","doi-asserted-by":"crossref","first-page":"2287","DOI":"10.3174\/ajnr.A4900","article-title":"Efficacy and safety of the Woven EndoBridge (WEB) device for the treatment of intracranial aneurysms: a systematic review and meta-analysis","volume":"37","author":"Asnafi S","year":"2016","journal-title":"Am J Neuroradiol"},{"issue":"1","key":"ref18","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1186\/s12883-020-1623-9","article-title":"SMART coils for intracranial aneurysm repair\u2013a single center experience","volume":"20","author":"Daniel B","year":"2020","journal-title":"BMC Neurol"},{"issue":"2","key":"ref19","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1148\/radiol.2020191842","article-title":"Intraoperative complications of endovascular treatment of intracranial aneurysms with coiling or balloon-assisted coiling in a prospective multicenter cohort of 1088 participants: analysis of recanalization after endovascular treatment of intracranial aneurysm (ARETA) study","volume":"295","author":"Pierot L","year":"2020","journal-title":"Radiology"},{"issue":"6","key":"ref20","doi-asserted-by":"crossref","first-page":"356","DOI":"10.2176\/nmc.oa.2020-0348","article-title":"Evaluation of the straightening phenomenon of various types of coils","volume":"61","author":"Ishida M","year":"2021","journal-title":"Neurol Med Chir (Tokyo)"},{"key":"ref21","article-title":"Intraprocedural rupture during endovascular treatment of intracranial aneurysm: clinical results and literature review","volume":"114","author":"Park YK","year":"2018","journal-title":"World Neurosurg"},{"issue":"4","key":"ref22","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1007\/s00234-006-0051-x","article-title":"Retrieval of prolapsed coils during endovascular treatment of cerebral aneurysms","volume":"48","author":"Dinc H","year":"2006","journal-title":"Neuroradiology"},{"key":"ref23","doi-asserted-by":"crossref","first-page":"737","DOI":"10.3389\/fneur.2019.00737","article-title":"TARGET\u00ae intracranial aneurysm coiling prospective multicenter registry: final analysis of peri-procedural and long-term safety and efficacy results","volume":"10","author":"Zaidat OO","year":"2019","journal-title":"Front Neurol"},{"key":"ref24","doi-asserted-by":"crossref","first-page":"637551","DOI":"10.3389\/fneur.2021.637551","article-title":"The SMART Registry: Long-term results on the utility of the penumbra SMART COIL system for treatment of intracranial aneurysms and other malformations","volume":"12","author":"Spiotta AM","year":"2021","journal-title":"Front Neurol"},{"key":"ref25","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1016\/j.wneu.2016.06.127","article-title":"Impact of coil packing density and coiling technique on occlusion rates for aneurysms treated with stent-assisted coil embolization","volume":"94","author":"Griessenauer CJ","year":"2016","journal-title":"World Neurosurg"},{"issue":"1","key":"ref26","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1136\/neurintsurg-2013-011049","article-title":"Final results of the multicenter, prospective Axium MicroFX for Endovascular Repair of IntraCranial Aneurysm Study (AMERICA)","volume":"7","author":"Fargen KM","year":"2015","journal-title":"J Neurointerv Surg"},{"issue":"2","key":"ref27","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1136\/jnis.2009.000547","article-title":"Balloon assisted treatment of intracranial aneurysms: the conglomerate coil mass technique","volume":"1","author":"Fiorella D","year":"2009","journal-title":"J Neurointerv Surg"},{"issue":"3","key":"ref28","doi-asserted-by":"crossref","first-page":"338","DOI":"10.1177\/15910199221087010","article-title":"Modified balloon-assisted coiling instead of acute stenting in the treatment of ruptured wide necked intracranial aneurysms","volume":"28","author":"Altay CM","year":"2022","journal-title":"Interv Neuroradiol"}],"container-title":["Acta Cir\u00fargica Brasileira"],"original-title":[],"link":[{"URL":"http:\/\/www.scielo.br\/scielo.php?script=sci_pdf&pid=S0102-86502025000100805&tlng=en","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,5,11]],"date-time":"2025-05-11T02:58:48Z","timestamp":1746932328000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.scielo.br\/scielo.php?script=sci_arttext&pid=S0102-86502025000100805&tlng=en"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025]]},"references-count":28,"alternative-id":["S0102-86502025000100805"],"URL":"https:\/\/doi.org\/10.1590\/acb403425","relation":{},"ISSN":["1678-2674","0102-8650"],"issn-type":[{"type":"electronic","value":"1678-2674"},{"type":"print","value":"0102-8650"}],"subject":[],"published":{"date-parts":[[2025]]},"article-number":"e403425"}}