{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T16:27:47Z","timestamp":1789576067849,"version":"build-2803163510"},"reference-count":56,"publisher":"FapUNIFESP (SciELO)","license":[{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"am","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100002322","name":"Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00edvel Superior","doi-asserted-by":"crossref","award":["001"],"award-info":[{"award-number":["001"]}],"id":[{"id":"10.13039\/501100002322","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acta Cir. Bras."],"abstract":"<jats:p>ABSTRACT  Purpose: To evaluate correlations between anthropometric tools for visceral fat assessment, including waist circumference (WC) and sagittal abdominal diameter (SAD), by computed tomography (CT)-derived visceral fat volume in patients with rectal adenocarcinoma.  Methods: This comparative cross-sectional study included 138 participants: rectal adenocarcinoma patients (group 1, n = 69) and controls (group 2, n = 69). Assessed variables were weight, body mass index (BMI), bioelectrical impedance analysis (BIA), WC, SAD, and CT-derived visceral fat volume measured with Fat Tissue (Syngo.Via VB20, Siemens). CT analysis was restricted to group 1.  Results: Median ages in groups 1 and 2 were 60 and 53 years, respectively (p &lt; 0.0008). CT revealed sex-based differences in visceral fat: 20.91 cm3 in females and 31.29 cm3 in males (p = 0.0043). WC and SAD demonstrated statistically significant correlations with CT-derived visceral fat in group 1 (p &lt; 0.0001).  Conclusion: WC and SAD correlated with CT-derived visceral fat in rectal adenocarcinoma patients. These exploratory findings require validation by larger studies with multivariable analyses to establish predictive value and clinical applicability.<\/jats:p>","DOI":"10.1590\/acb407925","type":"journal-article","created":{"date-parts":[[2025,11,10]],"date-time":"2025-11-10T15:02:04Z","timestamp":1762786924000},"source":"Crossref","is-referenced-by-count":1,"title":["Visceral fat assessment in rectal adenocarcinoma: the role of computed tomography, sagittal abdominal diameter, and waist circumference"],"prefix":"10.1590","volume":"40","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7581-7734","authenticated-orcid":false,"given":"Daniela Vicinansa","family":"Monaco-Ferreira","sequence":"first","affiliation":[{"name":"Universidade Estadual de Campinas,  Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8180-6254","authenticated-orcid":false,"given":"Dani\u00e9la Oliveira","family":"Magro","sequence":"additional","affiliation":[{"name":"Universidade Estadual de Campinas,  Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6694-1482","authenticated-orcid":false,"given":"Patr\u00edcia Prando","family":"Cardia","sequence":"additional","affiliation":[{"name":"Hospital Vera Cruz,  Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3226-0053","authenticated-orcid":false,"given":"Claudia Luciana","family":"Fratta","sequence":"additional","affiliation":[{"name":"Universidade Estadual de Campinas,  Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4691-7634","authenticated-orcid":false,"given":"Daniel Lahan","family":"Martins","sequence":"additional","affiliation":[{"name":"Hospital Vera Cruz,  Brazil; Universidade Estadual de Campinas,  Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8088-427X","authenticated-orcid":false,"given":"Carlos Augusto Real","family":"Martinez","sequence":"additional","affiliation":[{"name":"Universidade Estadual de Campinas,  Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0916-4138","authenticated-orcid":false,"given":"Cl\u00e1udio Saddy Rodrigues","family":"Coy","sequence":"additional","affiliation":[{"name":"Universidade Estadual de Campinas,  Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"530","published-online":{"date-parts":[[2025]]},"reference":[{"issue":"6","key":"ref1","first-page":"394","article-title":"Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries","volume":"68","author":"Bray F","year":"2018","journal-title":"CA Cancer J Clin"},{"issue":"1","key":"ref2","first-page":"10","article-title":"Cancer statistics, 2025","volume":"75","author":"Siegel RL","year":"2025","journal-title":"CA Cancer J Clin"},{"issue":"1","key":"ref3","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1093\/ije\/dyz078","article-title":"Smoking, drinking, diet and physical activity-modifiable lifestyle risk factors and their associations with age to first chronic disease","volume":"49","author":"Ng R","year":"2020","journal-title":"Int J Epidemiol"},{"issue":"2","key":"ref4","doi-asserted-by":"crossref","DOI":"10.1001\/jamanetworkopen.2020.37341","article-title":"Role of diet in colorectal cancer incidence: umbrella review of meta-analyses of prospective observational studies","volume":"4","author":"Veettil SK","year":"2021","journal-title":"JAMA Netw Open"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1186\/s12967-016-0772-5","article-title":"Obesity and colorectal cancer: molecular features of adipose tissue","volume":"14","author":"Martinez-Useros J","year":"2016","journal-title":"J Transl Med"},{"issue":"6","key":"ref6","doi-asserted-by":"crossref","first-page":"933","DOI":"10.1136\/gutjnl-2013-304701","article-title":"Obesity and colorectal cancer","volume":"62","author":"Bardou M","year":"2013","journal-title":"Gut"},{"issue":"4","key":"ref7","doi-asserted-by":"crossref","first-page":"924","DOI":"10.1210\/clinem\/dgad450","article-title":"New horizons: epidemiology of obesity, diabetes mellitus, and cancer prognosis","volume":"109","author":"Harborg S","year":"2024","journal-title":"J Clin Endocrinol Metab"},{"issue":"5","key":"ref8","doi-asserted-by":"crossref","first-page":"572","DOI":"10.1002\/bjs.10075","article-title":"Influence of body composition profile on outcomes following colorectal cancer surgery","volume":"103","author":"Malietzis G","year":"2016","journal-title":"Br J Surg"},{"issue":"3","key":"ref9","doi-asserted-by":"crossref","first-page":"556","DOI":"10.1093\/ajcn\/86.3.556","article-title":"Obesity and colon and rectal cancer risk: a meta analysis of prospective studies","volume":"86","author":"Larsson SC","year":"2007","journal-title":"Am J Clin Nutr"},{"issue":"9","key":"ref10","doi-asserted-by":"crossref","first-page":"2669","DOI":"10.1245\/s10434-018-6652-x","article-title":"Assessment of computed tomography defined muscle and adipose tissue features in relation to short-term outcomes after elective surgery for colorectal cancer: a multicenter approach","volume":"25","author":"Martin L","year":"2018","journal-title":"Ann Surg Oncol"},{"issue":"4","key":"ref11","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1080\/01635581.2014.894103","article-title":"Sarcopenia is linked to treatment toxicity in patients with metastatic colorectal cancer","volume":"66","author":"Barrett M","year":"2014","journal-title":"Nutr Cancer"},{"issue":"2","key":"ref12","first-page":"365","article-title":"Weight loss versus muscle loss: re evaluating inclusion criteria for future cancer cachexia interventional trials","volume":"25","author":"Roeland EJ","year":"2017","journal-title":"Support Care Cancer"},{"issue":"14","key":"ref13","doi-asserted-by":"crossref","first-page":"3008","DOI":"10.1002\/cncr.31405","article-title":"Muscle radiodensity and mortality in patients with colorectal cancer","volume":"124","author":"Kroenke CH","year":"2018","journal-title":"Cancer"},{"key":"ref14","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1016\/j.semcdb.2015.09.001","article-title":"Computed tomography-defined muscle and fat wasting are associated with cancer clinical outcomes","volume":"54","author":"Kazemi-Bajestani SM","year":"2016","journal-title":"Semin Cell Dev Biol"},{"issue":"2","key":"ref15","first-page":"412","article-title":"Nutritional status assessment in colorectal cancer patients","volume":"28","author":"Lopes JP","year":"2013","journal-title":"Nutr Hosp"},{"issue":"6","key":"ref16","doi-asserted-by":"crossref","DOI":"10.1042\/BSR20170945","article-title":"Abdominal obesity and colorectal cancer risk: systematic review and meta-analysis of prospective studies","volume":"37","author":"Dong Y","year":"2017","journal-title":"Biosci Rep"},{"issue":"5","key":"ref17","doi-asserted-by":"crossref","first-page":"997","DOI":"10.1139\/H08-075","article-title":"A practical and precise approach to quantification of body composition in cancer patients using computed tomography images acquired during routine care","volume":"33","author":"Mourtzakis M","year":"2008","journal-title":"Appl Physiol Nutr Metab"},{"issue":"2","key":"ref18","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1016\/j.ejso.2014.10.056","article-title":"The role of body composition evaluation by computerized tomography in determining colorectal cancer treatment outcomes: a systematic review","volume":"41","author":"Malietzis G","year":"2015","journal-title":"Eur J Surg Oncol"},{"issue":"2","key":"ref19","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1002\/jcsm.12158","article-title":"A comparative study of software programmes for cross-sectional skeletal muscle and adipose tissue measurements on abdominal computed tomography scans of rectal cancer patients","volume":"8","author":"van Vugt JL","year":"2017","journal-title":"J Cachexia Sarcopenia Muscle"},{"issue":"8","key":"ref20","doi-asserted-by":"crossref","first-page":"2241","DOI":"10.1245\/s10434-017-5829-z","article-title":"Prognostic value of computed tomography: measured parameters of body composition in primary operable gastrointestinal cancers","volume":"24","author":"Black D","year":"2017","journal-title":"Ann Surg Oncol"},{"issue":"10","key":"ref21","doi-asserted-by":"crossref","first-page":"1204","DOI":"10.1007\/s10147-019-01460-8","article-title":"Skeletal muscle loss during systemic chemotherapy for colorectal cancer indicates treatment response: a pooled analysis of a multicenter clinical trial (KSCC 1605-A)","volume":"24","author":"Sasaki S","year":"2019","journal-title":"Int J Clin Oncol"},{"issue":"Suppl.2","key":"ref22","doi-asserted-by":"crossref","first-page":"ii1","DOI":"10.1093\/annonc\/mdx810","article-title":"Sarcopenic obesity: hidden muscle wasting and its impact for survival and complications of cancer therapy","volume":"29","author":"Baracos VE","year":"2018","journal-title":"Ann Oncol"},{"issue":"4","key":"ref23","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1007\/s00384-016-2738-8","article-title":"Sarcopenia is associated with an increased risk of advanced colorectal neoplasia","volume":"32","author":"Park YS","year":"2017","journal-title":"Int J Colorectal Dis"},{"issue":"5","key":"ref24","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1080\/02656736.2017.1371342","article-title":"Preoperative nutritional risk assessment in patients undergoing cytoreductive surgery plus hyperthermic intraperitoneal chemotherapy for colorectal carcinomatosis","volume":"34","author":"Banaste N","year":"2018","journal-title":"Int J Hyperthermia"},{"issue":"1","key":"ref25","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1007\/s11605-012-2045-9","article-title":"Visceral obesity and colorectal cancer: are we missing the boat with BMI?","volume":"17","author":"Rickles AS","year":"2013","journal-title":"J Gastrointest Surg"},{"issue":"7","key":"ref26","doi-asserted-by":"crossref","first-page":"1745","DOI":"10.1007\/s11136-017-1539-z","article-title":"Associations of adipose and muscle tissue parameters at colorectal cancer diagnosis with long-term health-related quality of life","volume":"26","author":"van Roekel EH","journal-title":"Qual Life Res"},{"issue":"1","key":"ref27","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1186\/s12885-019-5319-8","article-title":"Prognostic value of adipose tissue and muscle mass in advanced colorectal cancer: a post hoc analysis of two non-randomized phase II trials","volume":"19","author":"Charette N","year":"2019","journal-title":"BMC Cancer"},{"issue":"1","key":"ref28","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1016\/j.clnu.2016.12.028","article-title":"Validity of bioelectrical impedance analysis in estimation of fat-free mass in colorectal cancer patients","volume":"37","author":"R\u00e6der H","year":"2018","journal-title":"Clin Nutr"},{"key":"ref29","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1016\/j.clnesp.2016.09.003","article-title":"Multi-frequency bioelectrical impedance analysis (BIA) compared to magnetic resonance imaging (MRI) for estimation of fat-free mass in colorectal cancer patients treated with chemotherapy","volume":"16","author":"Palle SS","year":"2016","journal-title":"Clin Nutr ESPEN"},{"issue":"6","key":"ref30","doi-asserted-by":"crossref","first-page":"980","DOI":"10.1590\/S0004-27302007000600013","article-title":"Validity and reliability of the sagittal abdominal diameter as a predictor of visceral abdominal fat","volume":"51","author":"Sampaio LR","year":"2007","journal-title":"Arq Bras Endocrinol Metabol"},{"issue":"2","key":"ref31","doi-asserted-by":"crossref","first-page":"283","DOI":"10.2337\/dc11-2451","article-title":"Sagittal abdominal diameter as a new predictor for incident diabetes","volume":"36","author":"Pajunen P","year":"2013","journal-title":"Diabetes Care"},{"issue":"5","key":"ref32","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0125365","article-title":"Sagittal abdominal diameter as a surrogate marker of insulin resistance in an admixtured population \u2013 Brazilian Metabolic Syndrome Study (BRAMS)","volume":"10","author":"Vasques AC","year":"2015","journal-title":"PLoS One"},{"issue":"1","key":"ref33","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1002\/jcsm.12234","article-title":"Sarcopenia is negatively associated with long-term outcomes in locally advanced rectal cancer","volume":"9","author":"Choi MH","year":"2018","journal-title":"J Cachexia Sarcopenia Muscle"},{"issue":"2","key":"ref34","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1590\/s0004-2803.202202000-52","article-title":"Evaluation of different tools for body composition assessment in colorectal cancer: a systematic review","volume":"59","author":"Monaco-Ferreira DV","year":"2022","journal-title":"Arq Gastroenterol"},{"issue":"1","key":"ref35","doi-asserted-by":"crossref","first-page":"644","DOI":"10.1186\/s12885-019-5837-4","article-title":"Impact of genetic mutations and nutritional status on the survival of patients with colorectal cancer","volume":"19","author":"Cavagnari MAV","year":"2019","journal-title":"BMC Cancer"},{"key":"ref36","series-title":"AJCC Cancer Staging Manual","volume-title":"Colon and rectum","year":"2017","edition":"8th ed."},{"key":"ref37","series-title":"Obesity: preventing and managing the global epidemic","year":"2000"},{"issue":"3","key":"ref38","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1038\/s41574-019-0310-7","article-title":"Waist circumference as a vital sign in clinical practice: a Consensus Statement from the IAS and ICCR Working Group on Visceral Obesity","volume":"16","author":"Ross R","year":"2020","journal-title":"Nat Rev Endocrinol"},{"key":"ref39","series-title":"Advances in body composition assessment","author":"Lohman TG","year":"1992"},{"issue":"7","key":"ref40","doi-asserted-by":"crossref","first-page":"655","DOI":"10.1038\/sj.ijo.0800643","article-title":"Sagittal abdominal diameter as a practical predictor of visceral fat","volume":"22","author":"Zamboni M","year":"1998","journal-title":"Int J Obes Relat Metab Disord"},{"issue":"5","key":"ref41","first-page":"511","article-title":"Different measurements of the sagittal abdominal diameter and waist perimeter in the prediction of HOMA-IR","volume":"93","author":"Vasques AC","year":"2009","journal-title":"Arq Bras Cardiol"},{"issue":"6","key":"ref42","doi-asserted-by":"crossref","first-page":"980","DOI":"10.1590\/S0004-27302007000600013","article-title":"Validity and reliability of the sagittal abdominal diameter as a predictor of visceral abdominal fat","volume":"51","author":"Sampaio LR","year":"2007","journal-title":"Arq Bras Endocrinol Metabol"},{"key":"ref43","series-title":"Syngo.via VB50 anatomy visualizer: visceral fat measurement","year":"2023"},{"issue":"3","key":"ref44","doi-asserted-by":"crossref","first-page":"500","DOI":"10.1038\/sj.ijo.0803454","article-title":"Comparison of anthropometric, area- and volume-based assessment of abdominal subcutaneous and visceral adipose tissue volumes using multi-detector computed tomography","volume":"31","author":"Maurovich-Horvat P","year":"2007","journal-title":"Int J Obes (Lond)"},{"key":"ref45","series-title":"SAS system for Windows, version 9.4","year":"2002"},{"key":"ref46","series-title":"Practical nonparametric statistics","author":"Conover WJ","year":"1971"},{"issue":"4","key":"ref47","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1016\/S0261-5614(03)00098-0","article-title":"ESPEN guidelines for nutrition screening 2002","volume":"22","author":"Kondrup J","year":"2003","journal-title":"Clin Nutr"},{"issue":"1","key":"ref48","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1200\/JCO.2014.56.1894","article-title":"Diagnostic criteria for the classification of cancer-associated weight loss","volume":"33","author":"Martin L","year":"2015","journal-title":"J Clin Oncol"},{"key":"ref49","first-page":"266","article-title":"The role of energy balance on colorectal cancer survival","volume":"14","author":"Purcell SA","year":"2018","journal-title":"Curr Colorectal Cancer Rep"},{"issue":"6","key":"ref50","doi-asserted-by":"crossref","first-page":"1368","DOI":"10.3390\/cancers12061368","article-title":"Association between abdominal obesity and incident colorectal cancer: a nationwide cohort study in Korea","volume":"12","author":"Nam GE","year":"2020","journal-title":"Cancers (Basel)"},{"issue":"6","key":"ref51","doi-asserted-by":"crossref","first-page":"1351","DOI":"10.1093\/ajcn\/48.6.1351","article-title":"Total and visceral adipose-tissue volumes derived from measurements with computed tomography in adult men and women: predictive equations","volume":"48","author":"Kvist H","year":"1988","journal-title":"Am J Clin Nutr"},{"issue":"3","key":"ref52","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1016\/j.nutres.2012.12.007","article-title":"Establishing computed tomography-defined visceral fat area thresholds for use in obesity-related cancer research","volume":"33","author":"Doyle SL","year":"2013","journal-title":"Nutr Res"},{"issue":"2","key":"ref53","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1002\/jcsm.12525","article-title":"Nutrition interventions to treat low muscle mass in cancer","volume":"11","author":"Prado CM","year":"2020","journal-title":"J Cachexia Sarcopenia Muscle"},{"issue":"11","key":"ref54","doi-asserted-by":"crossref","first-page":"4131","DOI":"10.1007\/s00330-016-4231-8","article-title":"CT-based compartmental quantification of adipose tissue versus body metrics in colorectal cancer patients","volume":"26","author":"Nattenmueller J","year":"2016","journal-title":"Eur Radiol"},{"issue":"5","key":"ref55","doi-asserted-by":"crossref","first-page":"722","DOI":"10.1097\/SLA.0b013e3182a6605a","article-title":"Waist circumference and waist\/hip ratio are better predictive risk factors for mortality and morbidity after colorectal surgery than body mass index and body surface area","volume":"258","author":"Kartheuser AH","year":"2013","journal-title":"Ann Surg"},{"issue":"4","key":"ref56","first-page":"477","article-title":"Comparison between abdominal fat measured by CT and anthropometric indices as prediction factors for mortality and morbidity after colorectal surgery","volume":"81","author":"Bachmann R","year":"2018","journal-title":"Acta Gastroenterol Belg"}],"container-title":["Acta Cir\u00fargica Brasileira"],"original-title":[],"link":[{"URL":"http:\/\/www.scielo.br\/scielo.php?script=sci_pdf&pid=S0102-86502025000100811&tlng=en","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,10]],"date-time":"2025-11-10T15:02:12Z","timestamp":1762786932000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.scielo.br\/scielo.php?script=sci_arttext&pid=S0102-86502025000100811&tlng=en"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025]]},"references-count":56,"alternative-id":["S0102-86502025000100811"],"URL":"https:\/\/doi.org\/10.1590\/acb407925","relation":{},"ISSN":["1678-2674","0102-8650"],"issn-type":[{"value":"1678-2674","type":"electronic"},{"value":"0102-8650","type":"print"}],"subject":[],"published":{"date-parts":[[2025]]},"article-number":"e407925"}}