{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,12]],"date-time":"2026-03-12T01:09:20Z","timestamp":1773277760452,"version":"3.50.1"},"reference-count":24,"publisher":"FapUNIFESP (SciELO)","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Arq Bras Endocrinol Metab"],"published-print":{"date-parts":[[2004,2]]},"abstract":"<jats:p>Fundamentalmente, a gl\u00e2ndula tir\u00f3ide, face \u00e0 car\u00eancia de iodo, se adapta por incremento da capta\u00e7\u00e3o deste halog\u00eanio, aumenta a sua massa glandular (b\u00f3cio), induz secre\u00e7\u00e3o preferencial de T3 e eleva a s\u00edntese e libera\u00e7\u00e3o de TSH. Os exames laboratoriais e de imagem permitem a comprova\u00e7\u00e3o dos mecanismos adaptativos. A iod\u00faria permite avalia\u00e7\u00e3o quantitativa do grau de car\u00eancia i\u00f3dica. Em algumas popula\u00e7\u00f5es, coexiste a influ\u00eancia de boc\u00edgenos naturais presentes nos alimentos consumidos localmente. O cretinismo end\u00eamico \u00e9 s\u00edndrome neurol\u00f3gica e end\u00f3crina que conduz o indiv\u00edduo a quadro severo de rebaixamento mental e surdo-mudez. No Brasil, as mol\u00e9stias associadas \u00e0 car\u00eancia de iodo foram sempre avaliadas por inqu\u00e9ritos nacionais em escolares. A corre\u00e7\u00e3o da defici\u00eancia de iodo se faz pela adi\u00e7\u00e3o de iodato de pot\u00e1ssio ao sal de consumo humano. V\u00e1rias leis e decretos foram elaborados tentando aperfei\u00e7oar o sistema universal de ioda\u00e7\u00e3o do sal, que, mais recentemente, foi aprimorado e tornou-se mais eficiente em propiciar iodo a toda popula\u00e7\u00e3o brasileira.<\/jats:p>","DOI":"10.1590\/s0004-27302004000100007","type":"journal-article","created":{"date-parts":[[2005,5,12]],"date-time":"2005-05-12T16:03:22Z","timestamp":1115913802000},"page":"53-61","source":"Crossref","is-referenced-by-count":20,"title":["Mol\u00e9stias associadas \u00e0 car\u00eancia cr\u00f4nica de iodo"],"prefix":"10.1590","volume":"48","author":[{"given":"Meyer","family":"Knobel","sequence":"first","affiliation":[{"name":"Universidade de S\u00e3o Paulo"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Geraldo","family":"Medeiros-Neto","sequence":"additional","affiliation":[{"name":"Universidade de S\u00e3o 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