{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,26]],"date-time":"2025-10-26T22:46:15Z","timestamp":1761518775277},"reference-count":17,"publisher":"FapUNIFESP (SciELO)","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Arq Bras Endocrinol Metab"],"published-print":{"date-parts":[[2004,4]]},"abstract":"<jats:p>Oitenta e tr\u00eas pacientes que receberam 3,7GBq (100mCi) ou 7,4GBq (200mCi) de I-131 ap\u00f3s a tireoidectomia total para carcinoma de tire\u00f3ide foram avaliados cl\u00ednica e laboratorialmente (dosagem da amilase s\u00e9rica), seguida da varredura p\u00f3s-dose. A sialoadenite foi definida na presen\u00e7a de hiperamilasemia (&gt; 200U\/L). Onze (13,25%) pacientes referiram dor local espont\u00e2nea ou \u00e0 mastiga\u00e7\u00e3o ap\u00f3s o tratamento. Observou-se hiperamilasemia em 31 (37,3%) pacientes no segundo dia p\u00f3s-tratamento. No s\u00e9timo dia, houve normaliza\u00e7\u00e3o da amilase em todos. A sialoadenite sintom\u00e1tica foi maior nos pacientes com capta\u00e7\u00e3o cervical residual que receberam 7,4GBq (70%). A capta\u00e7\u00e3o em topografia de gl\u00e2ndulas salivares esteve presente em 93,5% dos casos de sialoadenite (p &lt; 0,05). Observou-se correla\u00e7\u00e3o estatisticamente significante entre aus\u00eancia de met\u00e1stase \u00e0 dist\u00e2ncia e maior incid\u00eancia de sialoadenite (p &lt; 0,05). N\u00e3o houve correla\u00e7\u00e3o entre sialoadenite e massa remanescente cervical ou com a dose de I-131 administrada, atribu\u00edda ao tamanho da amostra. A sialoadenite p\u00f3s-terapia ablativa em altas doses \u00e9 uma complica\u00e7\u00e3o relativamente comum, com baixa repercuss\u00e3o cl\u00ednica, sendo a aus\u00eancia de met\u00e1stases \u00e0 dist\u00e2ncia um fator diretamente relacionado com o seu aparecimento.<\/jats:p>","DOI":"10.1590\/s0004-27302004000200016","type":"journal-article","created":{"date-parts":[[2005,5,12]],"date-time":"2005-05-12T16:04:00Z","timestamp":1115913840000},"page":"310-314","source":"Crossref","is-referenced-by-count":5,"title":["Sialoadenite ap\u00f3s terapia ablativa com altas doses de radioiodo no tratamento do carcinoma diferenciado de tire\u00f3ide"],"prefix":"10.1590","volume":"48","author":[{"given":"Pedro W.S.","family":"Ros\u00e1rio","sequence":"first","affiliation":[{"name":"Santa Casa de Belo Horizonte"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Frederico F.R.","family":"Maia","sequence":"additional","affiliation":[{"name":"Santa Casa de Belo 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