{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T20:57:53Z","timestamp":1792097873094,"version":"4.4.0"},"reference-count":10,"publisher":"FapUNIFESP (SciELO)","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Arq Bras Endocrinol Metab"],"published-print":{"date-parts":[[2004,4]]},"abstract":"<jats:p>Em pacientes com s\u00edndrome de Cushing, observa-se freq\u00fc\u00eancia aumentada de infec\u00e7\u00f5es oportunistas que possuem uma elevada mortalidade e est\u00e3o associadas \u00e0 gravidade do hipercortisolismo. Criptococose pulmonar \u00e9 uma destas infec\u00e7\u00f5es oportunistas e pode mimetizar uma neoplasia pulmonar, tornando o seu diagn\u00f3stico dif\u00edcil. Apresentamos um caso de um paciente do sexo masculino, jovem, com s\u00edndrome de Cushing ACTH-dependente e grave hipercortisolismo. O paciente obteve a cura ap\u00f3s cirurgia transfenoidal, mas desenvolveu quadro febril. Tomografia computadorizada de t\u00f3rax mostrou um n\u00f3dulo pulmonar que n\u00e3o se alterava em radiografias seriadas. A investiga\u00e7\u00e3o para tuberculose, infec\u00e7\u00e3o f\u00fangica e bacteriana foi inconclusiva, tornando a hip\u00f3tese de neoplasia pulmonar mais prov\u00e1vel. O paciente faleceu por sepse urin\u00e1ria. A necropsia, no entanto, demonstrou tratar-se de criptococose pseudotumoral. Pacientes com s\u00edndrome de Cushing e infiltrado pulmonar devem ser avaliados quanto \u00e0 infec\u00e7\u00e3o f\u00fangica, como Cryptococcus neoformans.<\/jats:p>","DOI":"10.1590\/s0004-27302004000200018","type":"journal-article","created":{"date-parts":[[2005,5,12]],"date-time":"2005-05-12T20:04:00Z","timestamp":1115928240000},"page":"318-323","source":"Crossref","is-referenced-by-count":2,"title":["Criptococose pulmonar pseudotumoral associada \u00e0 s\u00edndrome de Cushing"],"prefix":"10.1590","volume":"48","author":[{"given":"Paulo G.S.","family":"Lacativa","sequence":"first","affiliation":[{"name":"Universidade Federal do Rio de Janeiro"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ines","family":"Donangelo","sequence":"additional","affiliation":[{"name":"Universidade Federal do Rio de Janeiro"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M\u00e1rcia B.","family":"Wagman","sequence":"additional","affiliation":[{"name":"Universidade 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