{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,8]],"date-time":"2026-07-08T04:32:08Z","timestamp":1783485128224,"version":"3.55.0"},"reference-count":27,"publisher":"FapUNIFESP (SciELO)","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Arq Bras Endocrinol Metab"],"published-print":{"date-parts":[[2004,12]]},"abstract":"<jats:p>A ioda\u00e7\u00e3o do sal \u00e9 eficiente no combate \u00e0s doen\u00e7as decorrentes da defici\u00eancia de iodo, sendo empregada em todo territ\u00f3rio nacional desde 1995. O Estado de S\u00e3o Paulo \u00e9 considerado uma \u00e1rea ioda-suficiente. Para avaliar a ingesta de iodo, foram selecionados aleatoriamente 844 escolares entre 6 e 14 anos, de seis regi\u00f5es do Estado. Foram avaliados, sob o ponto de vista ecogr\u00e1fico da tire\u00f3ide, 423 meninos e 421 meninas. Os volumes da gl\u00e2ndula tire\u00f3ide elevaram-se progressivamente com a idade, guardando correla\u00e7\u00e3o positiva e significativa com a superf\u00edcie corporal. Cerca de 1,6% dos escolares apresentava b\u00f3cio. N\u00f3dulos, cistos, hemiagenesia foram detectados em 1,4% dos examinados. Notamos excessiva excre\u00e7\u00e3o urin\u00e1ria de iodo nesta popula\u00e7\u00e3o, cerca de 53% eliminou acima de 300&lt;FONT FACE=Symbol&gt;\u00b5&lt;\/FONT&gt;g Iodo\/L e valores acima de 600&lt;FONT FACE=Symbol&gt;\u00b5&lt;\/FONT&gt;gI\/L foram encontrados em 21% dos escolares. As amostras de sal dom\u00e9stico apresentavam valores entre 28,1 e 63,3mg Iodo\/kg de sal. Conclu\u00edmos que a popula\u00e7\u00e3o escolar do Estado de S\u00e3o Paulo apresenta excessiva ingest\u00e3o di\u00e1ria de iodo, a qual, extrapolada para a popula\u00e7\u00e3o em geral, pode induzir v\u00e1rias altera\u00e7\u00f5es da fun\u00e7\u00e3o tire\u00f3idea, como hipertiroidismo subcl\u00ednico (em idosos) e tireoidite cr\u00f4nica autoimune na popula\u00e7\u00e3o adulta, em geral.<\/jats:p>","DOI":"10.1590\/s0004-27302004000600010","type":"journal-article","created":{"date-parts":[[2005,5,12]],"date-time":"2005-05-12T20:05:13Z","timestamp":1115928313000},"page":"842-848","source":"Crossref","is-referenced-by-count":24,"title":["Avalia\u00e7\u00e3o ultra-sonogr\u00e1fica da tire\u00f3ide e determina\u00e7\u00e3o da iod\u00faria em escolares de diferentes regi\u00f5es do Estado de S\u00e3o Paulo"],"prefix":"10.1590","volume":"48","author":[{"given":"Glaucia C.","family":"Duarte","sequence":"first","affiliation":[{"name":"Universidade de S\u00e3o Paulo"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eduardo K.","family":"Tomimori","sequence":"additional","affiliation":[{"name":"Universidade de S\u00e3o Paulo"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ros\u00e2ngela A.","family":"Boriolli","sequence":"additional","affiliation":[{"name":"Instituto Adolfo Lutz"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jerenice E.","family":"Ferreira","sequence":"additional","affiliation":[{"name":"Instituto Adolfo Lutz"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Regina M.","family":"Catarino","sequence":"additional","affiliation":[{"name":"Instituto Adolfo Lutz"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rosalinda Y.A.","family":"Camargo","sequence":"additional","affiliation":[{"name":"Universidade de S\u00e3o Paulo"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Geraldo","family":"Medeiros-Neto","sequence":"additional","affiliation":[{"name":"Universidade de S\u00e3o Paulo"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"530","reference":[{"issue":"5","key":"ref1","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1089\/105072501300176390","article-title":"Iodine deficiency in the world: Do we stand at the turn of the century?","volume":"11","author":"Delange F","year":"2001","journal-title":"Thyroid","ISSN":"https:\/\/id.crossref.org\/issn\/1050-7256","issn-type":"print"},{"issue":"3","key":"ref2","first-page":"587","article-title":"Iodine deficiency disorders","volume":"77","author":"Boyages S","year":"1993","journal-title":"J Clin Endocrinol Metab","ISSN":"https:\/\/id.crossref.org\/issn\/0021-972X","issn-type":"print"},{"issue":"6","key":"ref3","doi-asserted-by":"crossref","first-page":"595","DOI":"10.1530\/eje.0.1440595","article-title":"A survey of iodine intake and thyroid volume in Dutch schoolchildren: reference values in an iodine-sufficient area and the effect of puberty","volume":"144","author":"Wiersinga WM","year":"2001","journal-title":"Eur J Endocrin"},{"issue":"12","key":"ref4","doi-asserted-by":"crossref","first-page":"1141","DOI":"10.1089\/10507250152740984","article-title":"Iodine deficiency in Azerbaijan after discontinuation of an iodine prophylaxis program: reassessment of iodine intake and goiter prevalence in schoolchildren","volume":"11","author":"Markou KB","year":"2001","journal-title":"Thyroid","ISSN":"https:\/\/id.crossref.org\/issn\/1050-7256","issn-type":"print"},{"issue":"1","key":"ref5","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1055\/s-2001-11009","article-title":"Representative data of iodine intake and urinary excretion in Germany","volume":"109","author":"Gartner R","year":"2001","journal-title":"Exp Clin Endocrinol Diabetes","ISSN":"https:\/\/id.crossref.org\/issn\/0947-7349","issn-type":"print"},{"issue":"2B","key":"ref6","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1079\/PHN2001138","article-title":"Iodine deficiency disorders in Europe","volume":"4","author":"Vitti P","year":"2001","journal-title":"Public Health Nutr"},{"issue":"1","key":"ref7","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1079\/BJN2001474","article-title":"Dietary iodine intake and urinary iodine excretion in a Danish population: effect of geography, supplements and food choice","volume":"87","author":"Rasmussen LB","year":"2002","journal-title":"Br J Nutr","ISSN":"https:\/\/id.crossref.org\/issn\/0007-1145","issn-type":"print"},{"issue":"5","key":"ref8","first-page":"459","article-title":"Environmental iodine intake affects the type of nonmalignant thyroid disease","volume":"11","author":"Lauberg P","year":"2001","journal-title":"Thyroid","ISSN":"https:\/\/id.crossref.org\/issn\/1050-7256","issn-type":"print"},{"issue":"2","key":"ref9","first-page":"31","article-title":"The salt iodization program in Brazil: a medical and political conundrum","volume":"16","author":"Medeiros-Neto, G","year":"2000","journal-title":"IDD News"},{"issue":"3","key":"ref10","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1017\/S0007114500001628","article-title":"Efficacy of oral iodised oil is associated with anthropometric status in severely iodine-deficient schoolchildren in rural Malawi","volume":"84","author":"Furn\u00e9e CA","year":"2000","journal-title":"Br J Nutr","ISSN":"https:\/\/id.crossref.org\/issn\/0007-1145","issn-type":"print"},{"issue":"2","key":"ref11","first-page":"71","article-title":"Radioiodine kinetics and thyroid function following the universal salt iodization","volume":"14","author":"Moorthy D","year":"2001","journal-title":"Nat Med J India"},{"key":"ref12","article-title":"Recommended iodine levels in salt and guidelines for monitoring their adequacy and effectiveness","year":"2004","journal-title":"Fifth Report on World Nutrition, WHO"},{"issue":"1","key":"ref13","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1089\/thy.1998.8.83","article-title":"Iodine-induced hyperthyroidism: occurrence and epidemiology","volume":"8","author":"Stanbury JB","year":"1998","journal-title":"Thyroid","ISSN":"https:\/\/id.crossref.org\/issn\/1050-7256","issn-type":"print"},{"key":"ref14","first-page":"605","article-title":"Evidence of thyroid volume increase in normal subjects receiving excess iodine","volume":"76","author":"Namba H","year":"1993","journal-title":"J Clin Endocrinol Metab","ISSN":"https:\/\/id.crossref.org\/issn\/0021-972X","issn-type":"print"},{"issue":"5","key":"ref15","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1530\/eje.0.1460613","article-title":"Epidemiological survey on the relationship between different iodine intakes and the prevalence of hyperthyroidism","volume":"146","author":"Yang F","year":"2002","journal-title":"Eur J Endocrinol","ISSN":"https:\/\/id.crossref.org\/issn\/0804-4643","issn-type":"print"},{"issue":"10","key":"ref16","doi-asserted-by":"crossref","first-page":"1633","DOI":"10.2105\/AJPH.90.10.1633","article-title":"Endemic goiter associated with high iodine intake","volume":"90","author":"Zhao J","year":"2000","journal-title":"Am J Public Health","ISSN":"https:\/\/id.crossref.org\/issn\/0090-0036","issn-type":"print"},{"issue":"1","key":"ref17","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1089\/thy.1998.8.101","article-title":"The prevention and management of iodine-induced hyperthyroidism and its cardiac features","volume":"8","author":"Dunn JT","year":"1998","journal-title":"Thyroid","ISSN":"https:\/\/id.crossref.org\/issn\/1050-7256","issn-type":"print"},{"key":"ref18","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1111\/j.1365-2265.1989.tb01269.x","article-title":"Thyroid autoimmunity in endemic goitre caused by excessive iodine intake","volume":"31","author":"Boyages S","year":"1998","journal-title":"Clin Endocrinol"},{"issue":"5","key":"ref19","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1089\/105072503322021151","article-title":"High prevalence of autoimmune thyroiditis in schoolchildren after elimination of iodine deficiency in northwester Greece","volume":"13","author":"Zois C","year":"2003","journal-title":"Thyroid","ISSN":"https:\/\/id.crossref.org\/issn\/1050-7256","issn-type":"print"},{"issue":"3","key":"ref20","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1055\/s-2000-7744","article-title":"Continuous rise of urinary iodine excretion and drop in thyroid gland size among adolescents in Mecklenburg-West-Pomerania from 1993 to 1997","volume":"108","author":"Hampel R","year":"2000","journal-title":"Exp Clin Endocrinol Diabetes","ISSN":"https:\/\/id.crossref.org\/issn\/0947-7349","issn-type":"print"},{"issue":"3","key":"ref21","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1515\/JPEM.2000.13.3.245","article-title":"Thyroid gland volume and urinary iodine excretion in children 6-11 years old in an endemic area","volume":"13","author":"Semiz S","year":"2000","journal-title":"J Pediatr Endocrinol Metab","ISSN":"https:\/\/id.crossref.org\/issn\/0334-018X","issn-type":"print"},{"issue":"7","key":"ref22","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1007\/BF03343600","article-title":"Evaluation of goiter endemia by ultrasound in schoolchildren in Val Sarmento Italy","volume":"22","author":"Lupoli G","year":"1999","journal-title":"J Endocrinol Invest","ISSN":"https:\/\/id.crossref.org\/issn\/0391-4097","issn-type":"print"},{"issue":"7","key":"ref23","doi-asserted-by":"crossref","first-page":"659","DOI":"10.1089\/105072501750362727","article-title":"Searching for iodine deficiency in schoolchildren from Brasil: the THYROMOBIL project","volume":"11","author":"Rossi A C","year":"2001","journal-title":"Thyroid","ISSN":"https:\/\/id.crossref.org\/issn\/1050-7256","issn-type":"print"},{"issue":"1","key":"ref24","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1590\/S0004-27302004000100007","article-title":"Mol\u00e9stias associadas \u00e0 car\u00eancia cr\u00f4nica de iodo","volume":"48","author":"Knobel M","year":"2004","journal-title":"Arq Bras Endocrinol Metab"},{"key":"ref25","first-page":"9","article-title":"Micro determination of iodine by a catalytic method","volume":"1","author":"Sandell EB","year":"1937","journal-title":"Mikrovekemica Acta"},{"issue":"2","key":"ref26","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1093\/clinchem\/42.2.239","article-title":"Ammonium persulfate: a safe alternative oxidizing reagent for measuring urinary iodine","volume":"42","author":"Pino S","year":"1996","journal-title":"Clin Chem","ISSN":"https:\/\/id.crossref.org\/issn\/0009-9147","issn-type":"print"},{"key":"ref27","doi-asserted-by":"crossref","DOI":"10.1089\/1050725041692909","article-title":"Iodine nutrition improves in Latin Am\u00e9rica","volume":"14","author":"Pretell E","year":"2004","journal-title":"Thyroid","ISSN":"https:\/\/id.crossref.org\/issn\/1050-7256","issn-type":"print"}],"container-title":["Arquivos Brasileiros de Endocrinologia &amp; Metabologia"],"original-title":[],"link":[{"URL":"http:\/\/www.scielo.br\/pdf\/abem\/v48n6\/a10v48n6.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,4,7]],"date-time":"2020-04-07T09:33:08Z","timestamp":1586251988000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.scielo.br\/scielo.php?script=sci_arttext&pid=S0004-27302004000600010&lng=pt&tlng=pt"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,12]]},"references-count":27,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2004,12]]}},"alternative-id":["S0004-27302004000600010"],"URL":"https:\/\/doi.org\/10.1590\/s0004-27302004000600010","relation":{},"ISSN":["0004-2730"],"issn-type":[{"value":"0004-2730","type":"electronic"}],"subject":[],"published":{"date-parts":[[2004,12]]}}}