{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,12]],"date-time":"2025-09-12T19:18:54Z","timestamp":1757704734705},"reference-count":29,"publisher":"FapUNIFESP (SciELO)","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Arq Bras Endocrinol Metab"],"published-print":{"date-parts":[[2005,4]]},"abstract":"<jats:p>O hiperparatireoidismo prim\u00e1rio (HPP) \u00e9 uma doen\u00e7a incomum na inf\u00e2ncia e na adolesc\u00eancia. A associa\u00e7\u00e3o de HPP e epifisi\u00f3lise de cabe\u00e7a do f\u00eamur \u00e9 rara, tendo sido descritos apenas quatro casos na literatura. Relatamos um caso de HPP por adenoma de paratire\u00f3ide, com dores e in\u00fameras deformidades \u00f3sseas, associado a epifisi\u00f3lise de cabe\u00e7a do f\u00eamur em um jovem de 18 anos. A an\u00e1lise laboratorial mostrou c\u00e1lcio de 13,7mg\/dL, paratorm\u00f4nio de 1.524pg\/mL e fosfatase alcalina de 3.449U\/L. As deformidades foram decorrentes de diagn\u00f3stico tardio e possivelmente pelo fato de a doen\u00e7a ter ocorrido na fase de estir\u00e3o puberal. A combina\u00e7\u00e3o de v\u00e1rios fatores metab\u00f3licos e mec\u00e2nicos provavelmente contribuiu para esta associa\u00e7\u00e3o. O paciente foi submetido \u00e0 remo\u00e7\u00e3o cir\u00fargica do adenoma, que costuma ser acompanhada por resolu\u00e7\u00e3o pronta da epifisi\u00f3lise. Desta forma, foi optado por conduta expectante quanto \u00e0 epifisi\u00f3lise da cabe\u00e7a do f\u00eamur, em conson\u00e2ncia com a literatura. Houve melhora das dores \u00f3sseas e normaliza\u00e7\u00e3o dos n\u00edveis de c\u00e1lcio e de paratorm\u00f4nio.<\/jats:p>","DOI":"10.1590\/s0004-27302005000200021","type":"journal-article","created":{"date-parts":[[2006,1,9]],"date-time":"2006-01-09T18:15:14Z","timestamp":1136830514000},"page":"314-318","source":"Crossref","is-referenced-by-count":5,"title":["Hiperparatireoidismo prim\u00e1rio associado a epifisi\u00f3lise de cabe\u00e7a do f\u00eamur em adolescente"],"prefix":"10.1590","volume":"49","author":[{"given":"Isabel Rey","family":"Madeira","sequence":"first","affiliation":[{"name":"Universidade do Estado do Rio de Janeiro; Hospital Universit\u00e1rio Pedro Ernesto"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marise","family":"Machado","sequence":"additional","affiliation":[{"name":"Universidade do Estado do Rio de Janeiro; Hospital Universit\u00e1rio Pedro Ernesto"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria Cristina 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