{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,29]],"date-time":"2025-10-29T13:01:34Z","timestamp":1761742894897},"reference-count":26,"publisher":"FapUNIFESP (SciELO)","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Arq Bras Endocrinol Metab"],"published-print":{"date-parts":[[2006,10]]},"abstract":"<jats:p>INTRODU\u00c7\u00c3O: A medida de PTH intra-operat\u00f3rio (PTH-IO) foi inicialmente descrita em 1988, sendo potencialmente \u00fatil na defini\u00e7\u00e3o de sucesso ap\u00f3s a paratiroidectomia. OBJETIVOS: Avaliar prospectivamente perfil de decaimento do PTH-IO e sua capacidade de prever sucesso cir\u00fargico no hiperparatiroidismo prim\u00e1rio (HPP) e secund\u00e1rio \u00e0 insufici\u00eancia renal (HPS). PACIENTES E M\u00c9TODOS: 109 pacientes operados entre 06\/2000 e 12\/2004, sendo 33 HPP, 76 HPS (52 em di\u00e1lise, 24 transplantados renais). PTH-IO: m\u00e9todo imunom\u00e9trico r\u00e1pido (Elecsys-PTH\/Immunoassay-Roche); tempo para resultado: 10 minutos. Coletas de sangue perif\u00e9rico nos tempos basal, 10 e 20 minutos p\u00f3s-paratiroidectomia. RESULTADOS: HPP: queda m\u00e9dia de PTH de 79,2% aos 10 minutos. HPS: queda m\u00e9dia de PTH de 85,8% e 87,6% aos 10 minutos nos pacientes di\u00e1lise e transplantados respectivamente. A cirurgia foi bem sucedida em todos, exceto em 2 pacientes (1 HPP, 1 HPS). Em ambos n\u00e3o houve queda PTH-IO, sendo constatado adenoma duplo no HPP e paratir\u00f3ide ect\u00f3pica no HPS. CONCLUS\u00c3O: Medida PTH-IO fornece resultados confi\u00e1veis em tempo r\u00e1pido, sendo capaz de discriminar persist\u00eancia da doen\u00e7a se mantidos n\u00edveis elevados.<\/jats:p>","DOI":"10.1590\/s0004-27302006000500007","type":"journal-article","created":{"date-parts":[[2006,12,12]],"date-time":"2006-12-12T16:55:57Z","timestamp":1165942557000},"page":"869-875","source":"Crossref","is-referenced-by-count":7,"title":["Utilidade da medida de PTH intra-operat\u00f3rio no tratamento cir\u00fargico do hiperparatiroidismo prim\u00e1rio e secund\u00e1rio: an\u00e1lise de 109 casos"],"prefix":"10.1590","volume":"50","author":[{"given":"Monique Nakayama","family":"Ohe","sequence":"first","affiliation":[{"name":"Universidade Federal de S\u00e3o Paulo"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rodrigo Oliveira","family":"Santos","sequence":"additional","affiliation":[{"name":"Universidade Federal de S\u00e3o 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