{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,4,1]],"date-time":"2022-04-01T13:23:35Z","timestamp":1648819415318},"reference-count":18,"publisher":"FapUNIFESP (SciELO)","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Arq Bras Endocrinol Metab"],"published-print":{"date-parts":[[2007,8]]},"abstract":"<jats:p>As histiocitoses s\u00e3o doen\u00e7as raras, resultantes de altera\u00e7\u00f5es na linhagem monoc\u00edtica-histioc\u00edtica, com manifesta\u00e7\u00f5es cl\u00ednicas diversas. Entre as s\u00edndromes cut\u00e2neas de c\u00e9lulas n\u00e3o-Langerhans, o xantoma disseminado \u00e9 a \u00fanica entidade desse grupo classicamente associada ao diabetes ins\u00edpido central (DIC). O caso cl\u00ednico relatado refere-se a um paciente de 30 anos de idade que, dois anos ap\u00f3s o diagn\u00f3stico de DIC, evoluiu com les\u00f5es cut\u00e2neas papulosas, erit\u00eamato-acastanhadas, difusas, discretas e n\u00e3o confluentes. Os achados histol\u00f3gicos, imuno-histoqu\u00edmicos e a microscopia eletr\u00f4nica mostraram resultados compat\u00edveis com a histiocitose de c\u00e9lulas n\u00e3o-Langerhans e sugestivos do xantogranuloma juvenil. A avalia\u00e7\u00e3o end\u00f3crino-metab\u00f3lica n\u00e3o mostrou altera\u00e7\u00f5es durante o seguimento por 10 anos, com exce\u00e7\u00e3o do DIC. A resson\u00e2ncia magn\u00e9tica da hip\u00f3fise demonstrou aus\u00eancia do sinal hiperintenso (mancha brilhante) correspondente \u00e0 neuro-hip\u00f3fise. As radiografias e a cintilografia dos ossos n\u00e3o mostraram les\u00f5es osteol\u00edticas. Este caso desperta a aten\u00e7\u00e3o para a import\u00e2ncia do exame da pele nos casos de DIC e de sua associa\u00e7\u00e3o com a histiocitose de c\u00e9lulas n\u00e3o-Langerhans de maneira mais ampla, e n\u00e3o restrita aos casos de xantoma disseminado.<\/jats:p>","DOI":"10.1590\/s0004-27302007000600019","type":"journal-article","created":{"date-parts":[[2007,11,16]],"date-time":"2007-11-16T03:18:51Z","timestamp":1195183131000},"page":"1018-1022","source":"Crossref","is-referenced-by-count":1,"title":["Histiocitose cut\u00e2nea n\u00e3o-Langerhans como causa de diabetes ins\u00edpido central"],"prefix":"10.1590","volume":"51","author":[{"given":"Paulo A.C.","family":"Miranda","sequence":"first","affiliation":[{"name":"Universidade Federal de Minas Gerais"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Silvana M.C.","family":"Miranda","sequence":"additional","affiliation":[{"name":"Universidade Federal de Minas Gerais"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fl\u00e1via V.","family":"Bittencourt","sequence":"additional","affiliation":[{"name":"Universidade Federal de Minas Gerais"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lucas J.C.","family":"Machado","sequence":"additional","affiliation":[{"name":"Universidade Federal de Minas Gerais"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lucia P.F. de","family":"Castro","sequence":"additional","affiliation":[{"name":"Universidade Federal de Minas Gerais"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Virginia H.R.","family":"Leite","sequence":"additional","affiliation":[{"name":"Universidade Federal de Minas Gerais"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M\u00e1rcio W.","family":"Lauria","sequence":"additional","affiliation":[{"name":"Universidade Federal de Minas Gerais"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Walter R.C.","family":"Braga","sequence":"additional","affiliation":[{"name":"Universidade Federal de Minas Gerais"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ant\u00f4nio Ribeiro de","family":"Oliveira Jr.","sequence":"additional","affiliation":[{"name":"Universidade Federal de Minas Gerais"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"530","reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1590\/S0004-27302003000400019","article-title":"Dist\u00farbios na secre\u00e7\u00e3o e a\u00e7\u00e3o do horm\u00f4nio antidiur\u00e9tico","volume":"47","author":"Naves LA","year":"2003","journal-title":"Arq Bras Endocrinol Metab"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"667","DOI":"10.1001\/archderm.1981.01650100069034","article-title":"Cutaneous syndromes of non-X histiocytosis: a review of the macrophage-histiocyte diseases of the skin","volume":"117","author":"Winkelmann RK","year":"1981","journal-title":"Arch Dermatol","ISSN":"http:\/\/id.crossref.org\/issn\/0003-987X","issn-type":"print"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"1370","DOI":"10.1210\/jcem.85.4.6501","article-title":"Hypothalamo-pituitary abnormalites in adult patients with Langerhans cell histiocytosis: clinical, endocrinological and radiological features and response to treatment","volume":"85","author":"Kaltsas GA","year":"2000","journal-title":"J Clin Endocrinol Metab","ISSN":"http:\/\/id.crossref.org\/issn\/0021-972X","issn-type":"print"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1046\/j.1365-2133.1998.02044.x","article-title":"Systemic xanthohistiocytoma: a variant of xantoma disseminatum?","volume":"138","author":"Ferrando J","year":"1998","journal-title":"Br J Dermatol","ISSN":"http:\/\/id.crossref.org\/issn\/0007-0963","issn-type":"print"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"1531","DOI":"10.1001\/archderm.1985.01660120057020","article-title":"Primary histiocytic dermatoses","volume":"121","author":"Ringel E","year":"1985","journal-title":"Arch Dermatol","ISSN":"http:\/\/id.crossref.org\/issn\/0003-987X","issn-type":"print"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1016\/S0190-9622(86)70049-2","article-title":"Juvenile xanthogranuloma with central nervous system lesions","volume":"14","author":"Flach DB","year":"1986","journal-title":"J Am Acad Dermatol","ISSN":"http:\/\/id.crossref.org\/issn\/0190-9622","issn-type":"print"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"458","DOI":"10.1590\/S0004-27302003000400018","article-title":"Altera\u00e7\u00f5es da haste hipofis\u00e1ria e suas implica\u00e7\u00f5es cl\u00ednicas","volume":"47","author":"Drummond JB","year":"2003","journal-title":"Arq Bras Endocrinol Metab"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1046\/j.1525-1470.2000.01779.x","article-title":"Benign cephalic histiocytosis with diabetes insipidus","volume":"17","author":"Weston WL","year":"2000","journal-title":"Pediatr Dermatol","ISSN":"http:\/\/id.crossref.org\/issn\/0736-8046","issn-type":"print"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1023\/B:PITU.0000011177.43408.56","article-title":"Xanthomatous pituitary lesions: a report of two cases and review of the literature","volume":"6","author":"Burt MG","year":"2003","journal-title":"Pituitary","ISSN":"http:\/\/id.crossref.org\/issn\/1386-341X","issn-type":"print"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"671","DOI":"10.1016\/S0889-8529(05)70207-3","article-title":"Antidiuretic hormone: Normal and disordered function","volume":"30","author":"Robertson GL","year":"2001","journal-title":"Endocrinol Metab Clin North Am","ISSN":"http:\/\/id.crossref.org\/issn\/0889-8529","issn-type":"print"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1001\/archderm.1962.01590110018003","article-title":"Xanthoma disseminatum","volume":"86","author":"Altman J","year":"1962","journal-title":"Arch Dermatol","ISSN":"http:\/\/id.crossref.org\/issn\/0003-987X","issn-type":"print"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"1094","DOI":"10.1001\/archderm.1977.01640080096018","article-title":"Xanthoma disseminatum: Clinical, metabolic, pathologic, and radiologic aspects","volume":"113","author":"Mishkel MA","year":"1977","journal-title":"Arch Dermatol","ISSN":"http:\/\/id.crossref.org\/issn\/0003-987X","issn-type":"print"},{"key":"ref13","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1016\/S0190-9622(97)80207-1","article-title":"Juvenile xanthogranuloma","volume":"36","author":"Hernandez-Martin A","year":"1997","journal-title":"J Am Acad Dermatol","ISSN":"http:\/\/id.crossref.org\/issn\/0190-9622","issn-type":"print"},{"key":"ref14","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1159\/000089027","article-title":"Multiple adult xanthogranuloma: case report and literature review","volume":"212","author":"Saad N","year":"2006","journal-title":"Dermatology","ISSN":"http:\/\/id.crossref.org\/issn\/0162-5446","issn-type":"print"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1097\/01.pas.0000147395.01229.06","article-title":"Juvenile xanthogranuloma in childhood and adolescence: a clinicopathologic study of 129 patients from the Kiel pediatric tumor registry","volume":"29","author":"Janssen D","year":"2005","journal-title":"Am J Surg Pathol","ISSN":"http:\/\/id.crossref.org\/issn\/0147-5185","issn-type":"print"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1097\/00000478-200305000-00003","article-title":"Juvenile xanthogranulomas in the first two decades of life: a clinicopathologic study of 174 cases with cutaneous and extracutaneous manifestations","volume":"27","author":"Dehner LP","year":"2003","journal-title":"Am J Surg Pathol","ISSN":"http:\/\/id.crossref.org\/issn\/0147-5185","issn-type":"print"},{"key":"ref17","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1111\/j.0736-8046.2004.21206.x","article-title":"Juvenile xanthogranuloma: a congenital giant form leading to a wide atrophic sequela","volume":"21","author":"Imiela A","year":"2004","journal-title":"Pediatr Dermatol","ISSN":"http:\/\/id.crossref.org\/issn\/0736-8046","issn-type":"print"},{"key":"ref18","first-page":"777","article-title":"Xantoma disseminatum, a rare cause of diabetes insipidus","volume":"76","author":"Odell WD","year":"1993","journal-title":"J Clin Endocrinol Metab","ISSN":"http:\/\/id.crossref.org\/issn\/0021-972X","issn-type":"print"}],"container-title":["Arquivos Brasileiros de Endocrinologia &amp; Metabologia"],"original-title":[],"link":[{"URL":"http:\/\/www.scielo.br\/pdf\/abem\/v51n6\/a19v51n6.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,5,25]],"date-time":"2017-05-25T20:47:03Z","timestamp":1495745223000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.scielo.br\/scielo.php?script=sci_arttext&pid=S0004-27302007000600019&lng=pt&tlng=pt"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,8]]},"references-count":18,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2007,8]]}},"alternative-id":["S0004-27302007000600019"],"URL":"https:\/\/doi.org\/10.1590\/s0004-27302007000600019","relation":{},"ISSN":["0004-2730"],"issn-type":[{"value":"0004-2730","type":"electronic"}],"subject":[],"published":{"date-parts":[[2007,8]]}}}