{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,6]],"date-time":"2025-12-06T16:56:37Z","timestamp":1765040197625},"reference-count":31,"publisher":"FapUNIFESP (SciELO)","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Arq Bras Endocrinol Metab"],"published-print":{"date-parts":[[2008,3]]},"abstract":"<jats:p>Tanto a bomba de infus\u00e3o de insulina quanto a terap\u00eautica de m\u00faltiplas doses de insulina (MDI) s\u00e3o meios efetivos de implementar o manejo intensivo do diabetes melito tipo 1 (DM1), com o objetivo de chegar a n\u00edveis glic\u00eamicos quase normais e obter-se um estilo de vida mais flex\u00edvel. A terapia com bomba de infus\u00e3o de insulina \u00e9 t\u00e3o segura quanto a MDI e tem vantagens sobre ela, sobretudo em pacientes com hipoglicemias freq\u00fcentes, com um fen\u00f4meno do alvorecer importante, com gastroparesia, na gravidez, em crian\u00e7as e em pacientes com DM1 e com um estilo de vida err\u00e1tico. A terapia com bomba de infus\u00e3o de insulina possibilita maior probabilidade de se alcan\u00e7ar melhor controle glic\u00eamico com menos hipoglicemia, hipoglicemias assintom\u00e1ticas e melhor qualidade de vida. Al\u00e9m disso, os riscos e os efeitos adversos da terap\u00eautica insul\u00ednica em pacientes com DM1 em insuliniza\u00e7\u00e3o intensiva s\u00e3o menores nos pacientes usando esta terapia, quando comparados a pacientes em MDI. Para tal, o ajuste cuidadoso das doses basais e de b\u00f3lus e o seguimento adequado do paciente s\u00e3o vitais.<\/jats:p>","DOI":"10.1590\/s0004-27302008000200022","type":"journal-article","created":{"date-parts":[[2008,4,24]],"date-time":"2008-04-24T00:18:39Z","timestamp":1208996319000},"page":"340-348","source":"Crossref","is-referenced-by-count":7,"title":["Uso de bomba de infus\u00e3o subcut\u00e2nea de insulina e suas indica\u00e7\u00f5es"],"prefix":"10.1590","volume":"52","author":[{"given":"Walter Jos\u00e9","family":"Minicucci","sequence":"first","affiliation":[{"name":"Universidade Estadual de Campinas,  Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"530","reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"977","DOI":"10.1056\/NEJM199309303291401","article-title":"The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin: Dependent diabetes mellitus","volume":"329","year":"1993","journal-title":"N Engl J Med","ISSN":"http:\/\/id.crossref.org\/issn\/0028-4793","issn-type":"print"},{"issue":"7339","key":"ref2","doi-asserted-by":"crossref","first-page":"705","DOI":"10.1136\/bmj.324.7339.705","article-title":"Glycaemic control with continuous subcutaneous insulin infusion compared with intensive insulin injections in patients with type 1 diabetes: meta-analysis of randomised controlled trials","volume":"324","author":"Pickup J","year":"2002","journal-title":"BMJ","ISSN":"http:\/\/id.crossref.org\/issn\/0959-8138","issn-type":"print"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"599","DOI":"10.1016\/S0889-8529(05)70269-3","article-title":"Novel forms of insulin delivery","volume":"26","author":"Saudek CD","year":"1997","journal-title":"Endocrinol Metab Clin North Am","ISSN":"http:\/\/id.crossref.org\/issn\/0889-8529","issn-type":"print"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"271","DOI":"10.2337\/diab.46.2.271","article-title":"hypoglycemia in the diabetes control and complications trial","volume":"46","year":"1997","journal-title":"Diabetes","ISSN":"http:\/\/id.crossref.org\/issn\/0012-1797","issn-type":"print"},{"key":"ref5","series-title":"Therapy for diabetes mellitus and related disorders","first-page":"224","volume-title":"Insulin pump therapy","author":"Bode B","year":"2004","edition":"4"},{"key":"ref6","series-title":"Diabetes mellitus","first-page":"281","volume-title":"Diabetes: uso de bomba de infus\u00e3o cont\u00ednua e sensores de glicose","author":"Minicucci WJ","year":"2006"},{"issue":"6","key":"ref7","doi-asserted-by":"crossref","first-page":"977","DOI":"10.2337\/diacare.21.6.977","article-title":"Improvement of HbA1c and blood glucose stability in IDDM patients treated with lispro insulin analog in external pumps","volume":"21","author":"Melki V","year":"1998","journal-title":"Diabetes Care","ISSN":"http:\/\/id.crossref.org\/issn\/0149-5992","issn-type":"print"},{"issue":"3","key":"ref8","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1002\/(SICI)1096-9136(199803)15:3<247::AID-DIA547>3.0.CO;2-T","article-title":"Human insulin analogue [LYS(B28), PRO(B29)]: the ideal pump insulin?","volume":"15","author":"Schmauss S","year":"1998","journal-title":"Diabet Med","ISSN":"http:\/\/id.crossref.org\/issn\/0742-3071","issn-type":"print"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"439","DOI":"10.2337\/diacare.25.3.439","article-title":"Comparison of insulin aspart with buffered regular insulin and insulin lispro in continuous subcutaneous insulin infusion: a randomized study in type 1 diabetes","volume":"25","author":"Bode B","year":"2002","journal-title":"Diabetes Care","ISSN":"http:\/\/id.crossref.org\/issn\/0149-5992","issn-type":"print"},{"issue":"11","key":"ref10","doi-asserted-by":"crossref","first-page":"1779","DOI":"10.2337\/diacare.22.11.1779","article-title":"Continuous subcutaneous insulin infusion: A new way to lower risk of severe hypoglycemia, improve metabolic control, and enhance coping in adolescents with type 1 diabetes","volume":"22","author":"Boland EA","year":"1999","journal-title":"Diabetes Care","ISSN":"http:\/\/id.crossref.org\/issn\/0149-5992","issn-type":"print"},{"key":"ref11","series-title":"Intensive diabetes manegement","first-page":"102","volume-title":"Insulin infusion pump therapy","author":"Klingensmith GJ","year":"2003","edition":"3"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"784","DOI":"10.2337\/diacare.22.5.784","article-title":"Use of insulin lispro in continuous subcutaneous insulin infusion treatment: Results of a multicenter trial. German Humalog-CSII Study Group","volume":"22","author":"Renner R","year":"1999","journal-title":"Diabetes Care","ISSN":"http:\/\/id.crossref.org\/issn\/0149-5992","issn-type":"print"},{"key":"ref13","article-title":"O papel da bomba de insulina nas estrat\u00e9gias de tratamento do diabetes: Posicionamento Oficial SBD 2007 n\u00ba 6","author":"Minicucci W","year":"2007","journal-title":"Rev Bras Med","ISSN":"http:\/\/id.crossref.org\/issn\/0034-7264","issn-type":"print"},{"key":"ref14","doi-asserted-by":"crossref","first-page":"324","DOI":"10.2337\/diacare.19.4.324","article-title":"Reduction in severe hypoglycemia with long-term continuous subcutaneous insulin infusion in type 1 diabetes","volume":"19","author":"Bode BW","year":"1996","journal-title":"Diabetes Care","ISSN":"http:\/\/id.crossref.org\/issn\/0149-5992","issn-type":"print"},{"key":"ref15","first-page":"41","article-title":"Continuous subcutaneous insulin infusion for the treatment of diabetic patients with hypoglycemic unawareness","volume":"4","author":"Hirsch IB","year":"1991","journal-title":"Diabet Nutr Metab"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"593","DOI":"10.2337\/diacare.25.3.593","article-title":"Continuous subcutaneous insulin infusion at 25 years: evidence base for the expanding use of insulin pump therapy in type 1 diabetes (review)","volume":"25","author":"Pickup J","year":"2002","journal-title":"Diabetes Care","ISSN":"http:\/\/id.crossref.org\/issn\/0149-5992","issn-type":"print"},{"issue":"4","key":"ref17","doi-asserted-by":"crossref","first-page":"1079","DOI":"10.2337\/diacare.26.4.1079","article-title":"Insulin pump therapy: a meta-analysis","volume":"26","author":"Weissberg-Benchell J","year":"2003","journal-title":"Diabetes Care","ISSN":"http:\/\/id.crossref.org\/issn\/0149-5992","issn-type":"print"},{"key":"ref18","doi-asserted-by":"crossref","first-page":"69","DOI":"10.3810\/pgm.2002.05.1200","article-title":"Insulin pump therapy in the 21st century: strategies for successful use in adults, adolescents, and children with diabetes (review)","volume":"111","author":"Bode BW","year":"2002","journal-title":"Postgrad Med","ISSN":"http:\/\/id.crossref.org\/issn\/0032-5481","issn-type":"print"},{"issue":"5","key":"ref19","doi-asserted-by":"crossref","first-page":"326","DOI":"10.1007\/BF00251817","article-title":"Pharmacokinetics of continuous subcutaneous insulin infusion","volume":"24","author":"Lauritzen T","year":"1983","journal-title":"Diabetologia","ISSN":"http:\/\/id.crossref.org\/issn\/0012-186X","issn-type":"print"},{"issue":"6","key":"ref20","doi-asserted-by":"crossref","first-page":"1283","DOI":"10.1067\/mob.2000.106182","article-title":"Benefits, risks, costs, and patient satisfaction associated with insulin pump therapy for the pregnancy complicated by type 1 diabetes mellitus","volume":"182","author":"Gabbe SG","year":"2000","journal-title":"Am J Obstet Gynecol","ISSN":"http:\/\/id.crossref.org\/issn\/0002-9378","issn-type":"print"},{"issue":"1","key":"ref21","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1007\/s00592-007-0239-5","article-title":"Outcome of pregnancy in women with type 1 diabetes intensively treated with continuous subcutaneous insulin infusion or conventional therapy: A case-control study","volume":"44","author":"Gim\u00e9nez M","year":"2007","journal-title":"Acta Diabetologica","ISSN":"http:\/\/id.crossref.org\/issn\/0940-5429","issn-type":"print"},{"key":"ref22","doi-asserted-by":"crossref","DOI":"10.1002\/14651858.CD005542.pub2","article-title":"Continuous subcutaneous insulin infusion versus multiple daily injections of insulin for pregnant women with diabetes","volume":"3","author":"Farrar D","year":"2007","journal-title":"Cochrane Database Syst Rev"},{"key":"ref23","doi-asserted-by":"crossref","first-page":"e1244","DOI":"10.1542\/peds.2006-0662","article-title":"Position Statement: Continuous subcutaneous insulin infusion in very young children with type 1 diabetes","volume":"118","author":"Eugster EA","year":"2006","journal-title":"Pediatrics","ISSN":"http:\/\/id.crossref.org\/issn\/0031-4005","issn-type":"print"},{"issue":"6","key":"ref24","doi-asserted-by":"crossref","first-page":"881","DOI":"10.1111\/j.1651-2227.2007.00301.x","article-title":"Sustained metabolic control and low rates of severe hypoglycaemic episodes in preschool diabetic children treated with continuous subscutaneous isulin infusion","volume":"96","author":"Pankowska E","year":"2007","journal-title":"Acta Paediatr","ISSN":"http:\/\/id.crossref.org\/issn\/0001-656X","issn-type":"print"},{"issue":"8","key":"ref25","doi-asserted-by":"crossref","first-page":"900","DOI":"10.1111\/j.1464-5491.2006.01935.x","article-title":"Long-term benefits of continuous subcutaneous insulin infusion in children with type 1 diabetes: a 4-year follow-up","volume":"23","author":"Sulli N","year":"2006","journal-title":"Diabet Med","ISSN":"http:\/\/id.crossref.org\/issn\/0742-3071","issn-type":"print"},{"issue":"6","key":"ref26","doi-asserted-by":"crossref","first-page":"1653","DOI":"10.2337\/dc07-9922","article-title":"Use of insulin pump therapy in the pediatric age-group: consensus statement from the European Society for Paediatric Endocrinology, the Lawson Wilkins Pediatric Endocrine Society, and the International Society for Pediatric and Adolescent Diabetes, endorsed by the American Diabetes Association and the European Association for the Study of Diabetes","volume":"30","author":"Phillip M","year":"2007","journal-title":"Diabetes Care","ISSN":"http:\/\/id.crossref.org\/issn\/0149-5992","issn-type":"print"},{"key":"ref27","doi-asserted-by":"crossref","DOI":"10.2337\/diacare.28.1.15","article-title":"A two-center randomized controlled feasibility trial of insulin pump therapy in young children with diabetes","author":"Wilson DM","year":"2005","journal-title":"Diabetes Care","ISSN":"http:\/\/id.crossref.org\/issn\/0149-5992","issn-type":"print"},{"issue":"2","key":"ref28","doi-asserted-by":"crossref","DOI":"10.2337\/diaspect.14.2.84","article-title":"View 2: insulin therapy in young children with diabetes","volume":"14","author":"Kaufman FR","year":"2001","journal-title":"Diabetes Spectrum","ISSN":"http:\/\/id.crossref.org\/issn\/1040-9165","issn-type":"print"},{"key":"ref29","doi-asserted-by":"crossref","first-page":"3265","DOI":"10.1001\/jama.1984.03350230025026","article-title":"Acute complications associated with insulin infusion pump therapy: report of experience with 161 patients","volume":"252","author":"Mecklenburg RS","year":"1984","journal-title":"JAMA","ISSN":"http:\/\/id.crossref.org\/issn\/0098-7484","issn-type":"print"},{"key":"ref30","doi-asserted-by":"crossref","first-page":"478","DOI":"10.2337\/diacare.10.4.478","article-title":"Acute cutaneous complications and catheter needle colonization during insulin pump therapy","volume":"10","author":"Chantelau E","year":"1987","journal-title":"Diabetes Care","ISSN":"http:\/\/id.crossref.org\/issn\/0149-5992","issn-type":"print"},{"key":"ref31","series-title":"Pumping insulin","author":"Walsh J","year":"2000","edition":"3"}],"container-title":["Arquivos Brasileiros de Endocrinologia &amp; Metabologia"],"original-title":[],"link":[{"URL":"http:\/\/www.scielo.br\/pdf\/abem\/v52n2\/22.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,5,25]],"date-time":"2017-05-25T20:42:25Z","timestamp":1495744945000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.scielo.br\/scielo.php?script=sci_arttext&pid=S0004-27302008000200022&lng=pt&tlng=pt"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,3]]},"references-count":31,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2008,3]]}},"alternative-id":["S0004-27302008000200022"],"URL":"https:\/\/doi.org\/10.1590\/s0004-27302008000200022","relation":{},"ISSN":["0004-2730"],"issn-type":[{"value":"0004-2730","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,3]]}}}