{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,6,16]],"date-time":"2022-06-16T16:06:19Z","timestamp":1655395579451},"reference-count":59,"publisher":"FapUNIFESP (SciELO)","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Arq Bras Endocrinol Metab"],"published-print":{"date-parts":[[2011,8]]},"abstract":"<jats:p>O efeito da radia\u00e7\u00e3o ionizante sobre a tireoide vem sendo estudado h\u00e1 v\u00e1rias d\u00e9cadas, e os acidentes nucleares t\u00eam sido a maior fonte de informa\u00e7\u00e3o. Existe associa\u00e7\u00e3o de hipotireoidismo, hipertireoidismo, n\u00f3dulos e c\u00e2ncer de tireoide com a radia\u00e7\u00e3o, mas os limiares de dose, mecanismos de les\u00e3o e alguns fatores de risco ainda n\u00e3o est\u00e3o bem estabelecidos. Crian\u00e7as s\u00e3o mais suscet\u00edveis \u00e0 les\u00e3o tireoidiana por radia\u00e7\u00e3o e necessitam de seguimento prolongado ap\u00f3s a exposi\u00e7\u00e3o. Esse tema adquire maior relev\u00e2ncia atualmente, pois um grande n\u00famero de pessoas tratadas com radioterapia para c\u00e2ncer na inf\u00e2ncia sobrevive e poder\u00e1 apresentar sequelas. Exames radiodiagn\u00f3sticos tamb\u00e9m representam fonte de exposi\u00e7\u00e3o \u00e0 radia\u00e7\u00e3o na popula\u00e7\u00e3o pedi\u00e1trica. Nesta revis\u00e3o, analisamos as diferentes altera\u00e7\u00f5es cl\u00ednico-patol\u00f3gicas e os mecanismos de les\u00f5es tireoidianas provocadas por tratamento radioter\u00e1pico e tomografia computadorizada em crian\u00e7as e adolescentes. \u00c9 importante conhecer esses dados para preven\u00e7\u00e3o, detec\u00e7\u00e3o precoce e tratamento da disfun\u00e7\u00e3o tireoidiana.<\/jats:p>","DOI":"10.1590\/s0004-27302011000600002","type":"journal-article","created":{"date-parts":[[2011,10,12]],"date-time":"2011-10-12T06:55:18Z","timestamp":1318402518000},"page":"359-366","source":"Crossref","is-referenced-by-count":1,"title":["Altera\u00e7\u00f5es tireoidianas associadas \u00e0 radia\u00e7\u00e3o externa em crian\u00e7as e adolescentes"],"prefix":"10.1590","volume":"55","author":[{"given":"Cassiane Cardoso","family":"Bonato","sequence":"first","affiliation":[{"name":"Universidade Federal do Rio Grande do Sul,  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